Optical Pressure Sensor for Eye with Embedded Interrogation System
An intraocular implant comprising: a pressure sensor implantable in an eye, wherein the pressure sensor comprises a substrate having a first side coupled to a membrane to define an optical cavity with a depth that varies based on an intraocular pressure of the eye; and an enclosure coupled to a second side of the substrate to define a hermetic cavity comprising a light source and a detector operable to interrogate the pressure sensor and obtain data corresponding to an intraocular pressure of the eye based on the interrogation.
1 . An intraocular implant comprising:
a pressure sensor implantable in an eye, wherein the pressure sensor comprises a substrate having a first side coupled to a membrane to define an optical cavity with a depth that varies based on an intraocular pressure of the eye; and
an enclosure coupled to a second side of the substrate to define a hermetic cavity comprising a light source and a detector operable to interrogate the pressure sensor and obtain data corresponding to an intraocular pressure of the eye based on the interrogation.
2 . The intraocular implant of claim 1 wherein the light source is a first light source, and the implant further comprises a second light source and a non-polarizing beam splitter positioned in the hermetic cavity to interrogate the pressure sensor.
3 . The intraocular implant of claim 2 wherein the first light source emits a beam of light having a first wavelength and the second light sources emits a beam of light having a second wavelength through the non-polarizing beam splitter to the detector to interrogate the pressure sensor.
4 . The intraocular implant of claim 1 wherein the implant further comprises an application-specific integrated circuit and a battery positioned in the hermetic cavity.
5 . The intraocular implant of claim 1 wherein the implant further comprises a light emitting diode in the hermetic cavity to optically transmit intraocular pressure data obtained by the interrogation of the pressure sensor to an external handheld reader device.
6 . The intraocular implant of claim 1 wherein the light source is arranged orthogonal to the detector.
7 . The intraocular implant of claim 1 wherein the light source is a single light source having an emission spectrum that changes over time.
8 . The intraocular implant of claim 1 further comprising a collimating lens and a beam splitter, and the light source emits a beam of light through the collimating lens to produce a number of light rays that pass through the beam splitter to interrogate different regions of the membrane.
9 . The intraocular implant of claim 8 wherein the detector is a first detector, and the implant further comprises a second detector, the first detect and the second detector are operable to receive a first light ray a second light ray reflected through the beam splitter, respectively.
10 . The intraocular implant of claim 1 wherein the pressure sensor is implanted in an anterior chamber of the eye.
11 . An intraocular pressure measurement system, comprising:
an intraocular implant implantable in an eye comprising a pressure sensor having a substrate having a first side coupled to a membrane to define an optical cavity with a depth that varies based on an intraocular pressure of the eye and an enclosure coupled to a second side of the substrate to define a hermetic cavity comprising a light source and a detector operable to interrogate the pressure sensor, and a transmitter operable to output data corresponding to an intraocular pressure of the eye based on the interrogation; and
an external reader device comprising a processor configured to receive the output data and, based on the output, estimate the intraocular pressure of the eye.
12 . The system of claim 11 wherein the light source is a first light source, and the implant further comprises a second light source and a non-polarizing beam splitter positioned in the hermetic cavity to interrogate the pressure sensor.
13 . The system of claim 12 wherein the first light source emits a beam of light having a first wavelength and the second light source emits a beam of light having a second wavelength through the non-polarizing beam splitter to the detector to interrogate the pressure sensor.
14 . The system of claim 11 wherein the implant further comprises an application-specific integrated circuit and a battery positioned in the hermetic cavity.
15 . The system of claim 11 wherein the implant further comprises a light emitting diode in the hermetic cavity to optically transmit intraocular pressure data obtained by the interrogation of the pressure sensor to an external handheld reader.
16 . The system of claim 11 wherein the light source is arranged orthogonal to the detector.
17 . The system of claim 11 wherein the light source is a single light source having an emission spectrum that changes over time.
18 . The system of claim 11 further comprising a collimating lens and a beam splitter, and the light source emits a beam of light through the collimating lens to produce a number of light rays that pass through the beam splitter to interrogate different regions of the membrane.
19 . The system of claim 18 wherein the detector is a first detector, and the implant further comprises a second detector, the first detect and the second detector are operable to receive a first light ray a second light ray reflected through the beam splitter, respectively.
20 . The system of claim 11 wherein the intraocular implant is implanted in an anterior chamber of the eye.