IP Library Granted Patent US 12,496,412
Granted Patent B2
US 12,496,412 · App. 18/468,755 · Granted Dec 16, 2025

Seal for an inhalation device

Inventors: Frank Bartels (Diepenbeek, BE); Juergen Rawert (Diepenbeek, BE)
Assignee: INVOX BELGIUM NV
A61M11/007A61M2205/0216A61M2205/0222
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Quick Facts
Patent No.
US 12,496,412
App. No.
18/468,755
Granted
Dec 16, 2025
Kind
B2
Abstract

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an improved seal construction for an inhalation device having a nebulizing nozzle and a piston which moves relative to a pumping chamber in order to generate pumping pressure and to an inhalation device comprising such seal. 5 An inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing ( 1 ), an impingement-type nozzle ( 6 ) for generating the nebulised aerosol by collision of at least two liquid jets, the nozzle ( 6 ) being firmly affixed to the user-facing side of the housing ( 1 ) such as to be immobile relative to the housing ( 1 ), inside the housing ( 1 ) the inhalation device comprises a reservoir ( 2 ) for storing a liquid (F), 10 a pumping device with a pumping chamber ( 3 ) for generation of a pressure inside said pumping chamber ( 3 ), wherein the pumping chamber ( 3 ) is fluidically connected with the reservoir ( 2 ), a riser pipe ( 5 ) which can be received with at least one reservoir-facing, interior end ( 5 A) in said pumping chamber ( 3 ), and said nozzle ( 6 ) which is connected liquid-tight to an exterior end ( 5 B) of the riser pipe ( 5 ), wherein the interior 15 volume of the pumping chamber ( 3 ) is changeable by means of relative motion of the pumping chamber to the riser pipe ( 5 ) or vice versa. A gap ( 10 ) can be present between an outside of said riser pipe ( 5 ) and an inside of said pumping chamber ( 3 ), and a seal ( 9 ) bridging said gap ( 10 ) in order to minimize pressure loss when a pressure is generated inside said pumping chamber ( 3 ). 20 Said seal ( 9 ) can be fixed to said outside of said riser pipe ( 5 ), and be moveable with respect to said inside of said pumping chamber ( 3 ).

Claims (52)

1 . An inhalation device for medically active liquids for generation of an aerosol, comprising:

a housing;

an impingement-type nozzle for generating the nebulized aerosol by collision of at least two liquid jets, the impingement-type nozzle being firmly affixed to a user-facing side of the housing so that it is immobile relative to the housing;

inside the housing, the inhalation device comprises:

a reservoir for storing a liquid;

a pumping device with a pumping chamber for generation of a pressure inside said pumping chamber, wherein the pumping chamber is fluidically connected with the reservoir;

a riser pipe comprising a reservoir-facing, interior end at least partially inserted in said pumping chamber, and

said impingement-type nozzle which is connected liquid-tight to an exterior end of the riser pipe;

wherein an interior volume of the pumping chamber is changeable due to relative motion of the pumping chamber with respect to the riser pipe or vice versa;

wherein a gap is present between an outside of said riser pipe and an inside of said pumping chamber, a seal bridging said gap in order to minimize pressure loss when a pressure is generated inside said pumping chamber; and

wherein said seal is fixed to said outside of said riser pipe.

2 . An inhalation device for medically active liquids for generation of an aerosol, comprising:

a housing;

an impingement-type nozzle for generating the nebulized aerosol by collision of at least two liquid jets, the impingement-type nozzle being firmly affixed to a user-facing side of the housing so that it is immobile relative to the housing;

inside the housing, the inhalation device comprises:

a reservoir for storing a liquid;

a pumping device with a pumping chamber for generation of a pressure inside said pumping chamber which is moveable relative to the housing or to the nozzle, wherein the pumping chamber is fluidically connected with the reservoir,

a riser pipe comprising a reservoir-facing, interior end at least partially inserted in said pumping chamber; and

said impingement-type nozzle which is connected liquid-tight to an exterior end of the riser pipe that is immobile and firmly attached to the housing or to the nozzle;

wherein an interior volume of the pumping chamber is changeable due to relative motion of the pumping chamber with respect to the riser pipe;

wherein a gap is present between an outside of said riser pipe and an inside of said pumping chamber, the gap bridged by a seal for minimizing pressure loss when a pressure is generated inside said pumping chamber.

3 . The inhalation device according to claim 2 , wherein

said seal is fixed to said outside of said riser pipe.

4 . The inhalation device according to claim 3 , wherein

said outside of said riser pipe exhibits a higher surface roughness than said inside of said pumping chamber.

5 . The inhalation device according to claim 3 , wherein

said riser pipe exhibits a constricted region or an expanded region.

6 . The inhalation device according to claim 2 , wherein

said seal is fixed to said inside of said pumping chamber and said outside of said riser pipe is moveable with respect to said seal.

7 . The inhalation device according to claim 6 , wherein

said outside of said riser pipe exhibits a lower surface roughness than said inside of said pumping chamber.

8 . The inhalation device according to claim 6 , wherein

said inside of said pumping chamber exhibits a recess or a rim.

9 . The inhalation device according to claim 1 , wherein

said seal is an O-ring, a flat ring, a piston ring, or a tube.

10 . The inhalation device according to claim 1 , wherein

said seal is made of an elastomer, Polytetrafluoroethylene, or a metal.

11 . The inhalation device according to claim 1 , wherein

the inhalation device comprises at least two of said seals, being arranged serially.

12 . The inhalation device according to claim 11 , wherein

at least two of said seals are spaced apart to prevent a tilting of the riser pipe in the pumping chamber.

13 . An inhalation device for medically active liquids for generation of an aerosol, comprising:

a housing;

an impingement-type nozzle for generating the nebulized aerosol by collision of at least two liquid jets, the impingement-type nozzle being firmly affixed to a user-facing side of the housing so that it is immobile relative to the housing;

inside the housing, the inhalation device comprises:

a reservoir for storing a liquid;

a pumping device with a pumping chamber for generation of a pressure inside said pumping chamber, wherein the pumping chamber is fluidically connected with the reservoir;

a riser pipe comprising a reservoir-facing, interior end at least partially inserted in said pumping chamber, and

said impingement-type nozzle which is connected liquid-tight to an exterior end of the riser pipe;

wherein an interior volume of the pumping chamber is changeable due to relative motion of the pumping chamber with respect to the riser pipe or vice versa;

wherein a gap is present between an outside of said riser pipe and an inside of said pumping chamber, a seal bridging said gap in order to minimize pressure loss when a pressure is generated inside said pumping chamber; and

wherein said seal is fixed in position on the interior end of said outside of said riser pipe.

Assignments (2)
CHANGE OF NAME Recorded Oct 3, 2024
From: SOFTHALE NV
To: INVOX BELGIUM NV
Reel/Frame 069105/0815 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2023
From: BARTELS, FRANK; RAWERT, JUERGEN
To: SOFTHALE NV
Reel/Frame 065164/0470 →
Priority Claims (1)
EP 17197136 · Oct 18, 2017 · regional
Continuity (3)
Continuation 16757544
Provisional Application 62574018 · Oct 18, 2017
Related Publication 20240075218A1 · Mar 7, 2024
References Cited (3)
US 20060016833A1 · Greiner-Perth · 2006 [cited by applicant]
US 20130200110A1 · Lee et al. · 2013 [cited by applicant]
WO 2016180975A1 · 2016 [cited by applicant]