IP Library Patent Application 18492739
Patent Application
App. No. 18/492,739

SYSTEMS AND METHODS FOR ENHANCING NEUROSTRUCTURAL DEVELOPMENT

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Quick Facts
Patent No.
US None
App. No.
18/492,739
Abstract

Systems and methods are provided for delivering energy impulses (and/or fields) to bodily tissues. In certain aspects, the systems and methods are particularly useful for temporarily or permanently improving intelligence, learning capacity, memory retention, recall, mood, alertness and/or sleep efficiency in human beings. In certain embodiments, the methods and devices enhance neurostructural development over a period of time by increasing neurogenesis, neuronal plasticity and/or neural connectivity efficiency, and/or by improving the chemical microenvironment of the evolving neural network. In some embodiments, these enhancements may provide temporary improvement to enable an individual to, for example, accomplish a particular task while under duress, sleep deprivation, stress, anxiety or the like. In other embodiments, these changes permanently enhance the intelligence, emotional stability, and overall brain health of the treated individual.

Claims (24)

1 . A method comprising:

applying an electrical impulse to a vagus nerve within the individual according to a stimulation protocol that includes at least two doses administered each day for a plurality of days, wherein the doses each have a duration of about ninety seconds to about 3 minutes; and

wherein the stimulation protocol is sufficient to enhance a neurostructural development in the individual.

2 . The method of claim 1 , wherein the stimulation protocol is sufficient to increase a connectivity of neurons within the brain of the individual.

3 . The method of claim 1 , wherein the stimulation protocol is sufficient to increase a neuronal plasticity within the brain of the individual.

4 . The method of claim 1 , wherein the doses are separated by a time frame of about five to 15 minutes.

5 . The method of claim 1 , wherein the stimulation protocol comprises 2 to 12 treatments/day.

6 . The method of claim 1 , wherein the stimulation protocol is administered every day for at least 90 days.

7 . The method of claim 1 , wherein the stimulation protocol is administered every day for at least one year.

8 . The method of claim 1 , wherein the individual is a child having an age of less than 18 years old.

9 . The method of claim 8 , wherein the age is less than 10 years old.

10 . The method of claim 1 , wherein the stimulation protocol is sufficient to increase an intelligence, emotional stability, memory retention, alertness and/or speed of learning of the individual.

11 . The method of claim 1 , wherein the electrical impulse is sufficient to modify a microglia in a central nervous system of the individual.

12 . The method of claim 15 , wherein the electrical impulse is sufficient to alter the microglia from a substantially pro-inflammatory state to a substantially non-inflammatory state.

13 . A method comprising:

applying an electrical impulse to a vagus nerve within the individual according to a stimulation protocol that includes at least two doses administered each day for a plurality of days, wherein the doses each have a duration of about ninety seconds to about 3 minutes; and

wherein the stimulation protocol is sufficient to increase an effectiveness of the neural network in the brain of the individual.

14 . The method of claim 13 , wherein the stimulation protocol is sufficient to increase a connectivity of neurons within the brain of the individual.

15 . The method of claim 13 , wherein the stimulation protocol is sufficient to increase a neuronal plasticity within the brain of the individual.

16 . The method of claim 13 , wherein the doses are separated by a time frame of about five to 15 minutes.

17 . The method of claim 13 , wherein the stimulation protocol comprises 2 to 12 treatments/day.

18 . The method of claim 13 wherein the stimulation protocol is administered every day for at least 90 days.

19 . The method of claim 13 , wherein the stimulation protocol is administered every day for at least one year.

20 . The method of claim 1 , wherein the stimulation protocol is sufficient to increase an intelligence, emotional stability, memory retention, alertness and/or speed of learning of the individual.

Assignments (2)
SECURITY INTEREST Recorded Aug 12, 2025
From: ELECTROCORE, INC.
To: AVENUE VENTURE OPPORTUNITIES FUND II, L.P.
Reel/Frame 072452/0559 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 20, 2024
From: SIMON, BRUCE J.; ERRICO, JOSEPH P.
To: ELECTROCORE, INC.
Reel/Frame 068647/0467 →