Granted Patent B2

US 12,414,727 · App. 18/496,781 · Granted Sep 16, 2025

Inventors: Xusheng Zhang (Shoreview, MN); Yuanzhen Liu (Palo Alto, CA)

Assignee: Medtronic, Inc.

A61B5/363A61B5/341A61B5/4836A61B5/7435A61B2560/02A61N1/3625A61N1/3702A61N1/39622

Abstract

Claims (104)

1. A medical device system comprising:

a processor configured to:

receive a first cardiac electrical signal and a second cardiac electrical signal associated with a tachyarrhythmia;

construct a third cardiac electrical signal from the first cardiac electrical signal and the second cardiac electrical signal;

determine a first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a first setting of a plurality of settings of a sensing control parameter;

determine a second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a second setting of a plurality of settings of the sensing control parameter;

determine at least one acceptable setting of the sensing control parameter based on at least the first predicted time to detect the tachyarrhythmia and the second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal; and

generate an output based on the determined acceptable setting of the sensing control parameter.

2. The medical device system of claim 1 , wherein the processor is further configured to:

for at least one of the first cardiac electrical signal, the second cardiac electrical signal and the constructed third cardiac electrical signal, determine a plurality of predicted times to detect the tachyarrhythmia, where each of the plurality of predicted times to detect the tachyarrhythmia is determined for a respective one of a plurality of settings of the sensing control parameter;

determine that at least one of the plurality of the predicted times to detect the tachyarrhythmia is within a tachyarrhythmia detection time limit; and

determine the at least one acceptable setting of the sensing control parameter by identifying at least one of the plurality of settings of the sensing control parameter for which the determined predicted time of the plurality of predicted times to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit.

3. The medical device system of claim 2 , wherein the processor is further configured to:

determine an actual time to detect the tachyarrhythmia from one of the first cardiac electrical signal or the second cardiac electrical signal; and

determine the tachyarrhythmia detection time limit by:

determining a minimum time to detect the tachyarrhythmia from among the actual time to detect the tachyarrhythmia, the first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal, and the plurality of predicted times to detect the tachyarrhythmia; and

determining the tachyarrhythmia detection time limit based on the minimum time to detect the tachyarrhythmia.

4. The medical device system of claim 2 wherein the processor is further configured to:

determine each of the plurality of predicted times to detect the tachyarrhythmia for the respective one of the plurality of settings of the sensing control parameter by determining each of the plurality of predicted times to detect the tachyarrhythmia for each of a plurality of sensitivity settings used to set a lowest amplitude of a cardiac event sensing threshold; and

determine the at least one acceptable setting of the sensing control parameter by:

determining a highest value of the plurality of sensitivity settings for which the determined predicted time to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit; and

determining the at least one acceptable setting of the sensing control parameter by determining a sensitivity that is a factor of the highest value of the plurality of sensitivity settings for which the determined predicted time to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit.

5. The medical device system of claim 1 wherein the processor is further configured to determine the first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal by:

determining sensed cardiac events from the constructed third cardiac signal;

determining sensed cardiac event intervals from the sensed cardiac events; and

determining the first predicted time to detect the tachyarrhythmia based on the determined sensed cardiac event intervals.

6. The medical device system of claim 1 wherein the processor is further configured to determine the at least one acceptable setting of the sensing control parameter by determining at least one of:

a sensing electrode vector;

a sensitivity used to set a cardiac event sensing threshold amplitude;

a percentage used to set a starting amplitude of the cardiac event sensing threshold amplitude;

a percentage used to set an intermediate amplitude of the cardiac event sensing threshold amplitude; or

a time interval used for making an amplitude adjustment to the cardiac event sensing threshold amplitude.

7. The medical device system of claim 1 further comprising

a sensing circuit configured to sense the first cardiac electrical signal and the second cardiac electrical signal;

a control circuit configured to detect the tachyarrhythmia from at least one of the first cardiac electrical signal and the second cardiac electrical signal; and

a therapy delivery circuit configured to deliver a therapy in response to the control circuit detecting the tachyarrhythmia.

8. The medical device system of claim 7 further comprising:

an implantable medical device comprising:

a housing enclosing the sensing circuit, the control circuit and the therapy delivery circuit; and

a first telemetry circuit configured to transmit the first cardiac electrical signal and the second cardiac electrical signal; and

an external device comprising:

a second telemetry configured to receive the first cardiac electrical signal and the second cardiac electrical signal transmitted by the first telemetry circuit;

the processor configured to receive the first cardiac electrical signal and the second cardiac electrical signal via the second telemetry circuit; and

a display unit configured to display the output generated by the processor.

9. The medical device system of claim 8 , wherein

the processor is further configured to:

for at least one of the first cardiac electrical signal, the second cardiac electrical signal and the constructed third cardiac electrical signal, determine a plurality of predicted times to detect the tachyarrhythmia, where each of the plurality of predicted times to detect the tachyarrhythmia are determined for a respective one of a plurality of sensitivity settings;

generate the output by:

for each one of the plurality of sensitivity settings determining a safety margin for sensing cardiac events; and

determining the at least one acceptable sensing control parameter by determining an acceptable sensitivity setting based on at least the determined safety margins and the plurality of predicted times to detect the tachyarrhythmia; and

the display unit is further configured to display at least a portion of the plurality of predicted times to detect the tachyarrhythmia along with a corresponding sensitivity setting and a corresponding determined safety margin.

10. A method comprising:

receiving a first cardiac electrical signal and a second cardiac electrical signal associated with a tachyarrhythmia;

constructing a third cardiac electrical signal from the first cardiac electrical signal and the second cardiac electrical signal;

determining a first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a first setting of a plurality of settings of a sensing control parameter;

determining a second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a second setting of a plurality of settings of the sensing control parameter;

determining at least one acceptable setting of the sensing control parameter based on at least the first predicted time to detect the tachyarrhythmia and the second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal; and

generating an output based on the determined acceptable setting of the sensing control parameter.

11. The method of claim 10 further comprising:

for at least one of the first cardiac electrical signal, the second cardiac electrical signal and the constructed third cardiac electrical signal, determining a plurality of predicted times to detect the tachyarrhythmia, where each of the plurality of predicted times to detect the tachyarrhythmia is determined for a respective one of a plurality of settings of the sensing control parameter;

determining that at least one of the plurality of the predicted times to detect the tachyarrhythmia is within a tachyarrhythmia detection time limit; and

determining the at least one acceptable setting of the sensing control parameter by identifying at least one of the plurality of settings of the sensing control parameter for which the determined predicted time to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit.

12. The method of claim 11 further comprising:

determining an actual time to detect the tachyarrhythmia from one of the first cardiac electrical signal or the second cardiac electrical signal; and

determining the tachyarrhythmia detection time limit by:

determining a minimum time to detect the tachyarrhythmia from among the actual time to detect the tachyarrhythmia, the first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal, and the plurality of predicted times to detect the tachyarrhythmia; and

determining the tachyarrhythmia detection time limit based on the minimum time to detect the tachyarrhythmia.

13. The method of claim 11 further comprising:

determining each of the plurality of predicted times to detect the tachyarrhythmia for the respective one of the plurality of settings of the sensing control parameter comprises determining each of the plurality of predicted times to detect the tachyarrhythmia for each of a plurality of sensitivity settings used to set a lowest amplitude of a cardiac event sensing threshold; and

determining the at least one acceptable setting of the sensing control parameter by:

determining a highest value of the plurality of sensitivity settings for which the determined predicted time to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit; and

determining the at least one acceptable setting of the sensing control parameter by determining a sensitivity that is a factor of the highest value of the plurality of sensitivity settings for which the determined predicted time to detect the tachyarrhythmia is within the tachyarrhythmia detection time limit.

14. The method of claim 10 wherein determining the first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal comprises:

determining sensed cardiac events from the constructed third cardiac signal;

determining sensed cardiac event intervals from the sensed cardiac events; and

determining the first predicted time to detect the tachyarrhythmia based on the determined sensed cardiac event intervals.

15. The method of claim 10 wherein determining the at least one acceptable setting of the sensing control parameter comprises determining at least one of:

a sensing electrode vector;

a sensitivity used to set a cardiac event sensing threshold amplitude;

a percentage used to set a starting amplitude of the cardiac event sensing threshold amplitude;

a percentage used to set an intermediate amplitude of the cardiac event sensing threshold amplitude; or

a time interval used for making an amplitude adjustment to the cardiac event sensing threshold amplitude.

16. The method of claim 10 further comprising:

sensing the first cardiac electrical signal and the second cardiac electrical signal;

detecting the tachyarrhythmia from at least one of the first cardiac electrical signal and the second cardiac electrical signal; and

delivering a therapy in response to detecting the tachyarrhythmia.

17. The method of claim 16 further comprising:

transmitting the first cardiac electrical signal and the second cardiac electrical signal by a first telemetry circuit;

receiving the first cardiac electrical signal and the second cardiac electrical signal via a second telemetry circuit;

displaying by a display unit the generated output.

18. The method of claim 17 further comprising:

for at least one of the first cardiac electrical signal, the second cardiac electrical signal and the constructed third cardiac electrical signal, determining a plurality of predicted times to detect the tachyarrhythmia, where each of the plurality of predicted times to detect the tachyarrhythmia are determined for a respective one of a plurality of sensitivity settings;

generating the output by:

for each one of the plurality of sensitivity settings, determining a safety margin for sensing cardiac events; and

determining the at least one acceptable sensing control parameter by determining an acceptable sensitivity setting based on at least the determined safety margins and the plurality of predicted times to detect the tachyarrhythmia; and

displaying at least a portion of the plurality of predicted times to detect the tachyarrhythmia along with a corresponding sensitivity setting and a corresponding determined safety margin.

19. A non-transitory computer readable medium storing a set of instructions that when executed by processing circuitry of a medical device system cause the medical device system to:

receive a first cardiac electrical signal and a second cardiac electrical signal associated with a tachyarrhythmia;

construct a third cardiac electrical signal from the first cardiac electrical signal and the second cardiac electrical signal;

determine a first predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a first setting of a plurality of settings of a sensing control parameter;

determine a second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal according to a second setting of a plurality of settings of the sensing control parameter;

determine at least one acceptable setting of the sensing control parameter based on at least the first predicted time to detect the tachyarrhythmia and the second predicted time to detect the tachyarrhythmia from the constructed third cardiac electrical signal;

generate an output based on the determined acceptable setting of the sensing control parameter; and

display the generated output including the determined acceptable setting of the sensing control parameter.

Assignments (1)

Continuity (4)

References Cited (21)