Granted Patent B2

US 12,239,333 · App. 18/497,249 · Granted Mar 4, 2025

Inventors: Richard Quick (Mission Viejo, CA); Benjamin Edward Merritt (San Clemente, CA); John Coleman Thress (Capistrano Beach, CA); Paul Lubock (Monarch Beach, CA); Thomas M. Tu (Louisville, KY)

Assignee: Inari Medical, Inc.

A61B17/22031A61B17/22A61B17/221A61M25/0082A61M39/06A61B2017/00907A61B2017/22034A61B2017/22042A61B2017/22079A61B2017/22094A61B2217/005A61M2210/12

Abstract

Claims (102)

1. A clot collection reservoir, comprising:

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to an aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to an aspiration source, wherein the second port provides a second fluid path from the chamber; and

a filter removably positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port;

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port; and

wherein the housing is at least partially transparent to permit visualization of the clot material in the chamber outside the interior region.

2. The clot collection reservoir of claim 1 wherein the second port is positioned proximate to the second housing end portion.

3. The clot collection reservoir of claim 1 , further comprising a cap configured to be releasably coupled to the second housing end portion, wherein the cap is removable from the housing to provide access to the filter.

4. The clot collection reservoir of claim 1 wherein the first filter end portion is curved.

5. The clot collection reservoir of claim 1 wherein the source of aspiration is configured to generate the negative pressure in the chamber via the second port to draw the clot material against the first filter end portion.

6. The clot collection reservoir of claim 1 wherein the housing is entirely transparent, and wherein the first port is integrally formed with the housing.

7. The clot collection reservoir of claim 1 wherein the first filter end portion is positioned closer to the first housing end portion than the second filter end portion, and wherein the second filter end portion is positioned closer to the second housing end portion than the first filter end portion.

8. A clot collection reservoir, comprising:

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to an aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to an aspiration source, wherein the second port provides a second fluid path from the chamber;

a cap configured to be releasably coupled to the second housing end portion; and

a filter coupled to the cap and configured to be positioned when the chamber when the cap is releasably coupled to the second housing end portion, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port;

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port;

wherein the housing is at least partially transparent to permit visualization of the clot material in the chamber outside the interior region; and

wherein the cap is removable from the housing to provide access to the filter.

9. A clot collection reservoir, comprising:

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to an aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to an aspiration source, wherein the second port provides a second fluid path from the chamber;

a cap configured to be releasably coupled to the second housing end portion; and

a filter positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port;

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port;

wherein the housing is at least partially transparent to permit visualization of the clot material in the chamber outside the interior region; and

wherein the cap and the filter are removable from the housing to provide access to the clot material within the chamber.

10. A clot treatment system, comprising:

an aspiration catheter configured to be intravascularly positioned proximate to clot material within a blood vessel of a patient;

an aspiration source; and

a clot collection reservoir, comprising—

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to the aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to the aspiration source, wherein the second port provides a second fluid path to the chamber; and

a filter positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port;

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port; and

wherein the filter is removably positioned within the chamber to provide access to the clot material within the chamber.

11. The clot treatment system of claim 10 wherein the housing is at least partially transparent to permit visualization of the clot material in the chamber outside the interior region.

12. The clot treatment system of claim 10 wherein the second port is positioned proximate to the second housing end portion.

13. The clot treatment system of claim 10 wherein the clot collection reservoir is spaced apart from the aspiration source, and further comprising at least one tube fluidly coupling the second port to the aspiration source.

14. A clot treatment system, comprising:

an aspiration catheter configured to be intravascularly positioned proximate to clot material within a blood vessel of a patient;

an aspiration source; and

a clot collection reservoir, comprising—

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to the aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to the aspiration source, wherein the second port provides a second fluid path to the chamber;

a cap configured to be releasably coupled to the second housing end portion; and

a filter positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port;

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port; and

wherein the cap and the filter are removable from the housing to provide access to the clot material within the chamber.

15. A clot treatment system, comprising:

an aspiration catheter configured to be intravascularly positioned proximate to clot material within a blood vessel of a patient;

an aspiration source;

a clot collection reservoir, comprising—

a housing defining a sealed chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to the aspiration catheter, wherein the first port is positioned proximate to the first housing end portion and provides a first fluid path to the chamber;

a second port configured to be fluidly coupled to the aspiration source, wherein the second port provides a second fluid path to the chamber; and

a filter positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port; and

a valve positioned between the clot collection reservoir and the aspiration catheter, wherein the valve is user-actuatable to move between (a) an open position in which the first port is fluidly connected to the aspiration catheter and (b) a closed position in which the first port is fluidly disconnected from the aspiration catheter;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port; and

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port.

16. The clot treatment system of claim 15 wherein the aspiration source is configured to generate the negative pressure in the chamber with the valve in the closed position, and wherein the valve is configured to be moved to the open position to apply the negative pressure to the aspiration catheter.

17. A clot treatment system, comprising:

an aspiration catheter configured to be intravascularly positioned proximate to clot material within a blood vessel of a patient;

a hemostasis valve coupled to a proximal portion of the aspiration catheter;

at least one tube fluidly coupling the first port to a portion of the aspiration catheter distal of the hemostasis valve;

an aspiration source; and

a clot collection reservoir, comprising—

a housing defining a chamber and having a first housing end portion and a second housing end portion opposite the first housing end portion;

a first port configured to be fluidly coupled to the aspiration catheter, wherein the first port is positioned proximate to the first housing end portion;

a second port configured to be fluidly coupled to the aspiration source; and

a filter positioned within the chamber, wherein the filter has a substantially cylindrical shape extending from a first filter end portion to a second filter end portion, and wherein the filter extends continuously about the first filter end portion such that the filter encloses an interior region around the second port;

wherein the aspiration source is configured to generate negative pressure in the chamber via the second port to (a) draw blood and clot material from the aspiration catheter through the first port into the chamber and (b) draw blood through the filter into the interior region and through the second port; and

wherein the filter is configured to inhibit the clot material from passing through the filter into the interior region and through the second port.

18. The clot treatment system of claim 17 wherein the hemostasis valve comprises:

a tubular member;

a button; and

a filament coupled to the button and the tubular member, wherein the button is actuatable to loosen the filament to unseal the hemostasis valve.

19. The clot treatment system of claim 17 wherein the aspiration source is fluidly couplable to the at least one tube.

20. The clot treatment system of claim 17 wherein the hemostasis valve is configured to receive an instrument therethrough.

21. The clot treatment system of claim 17 wherein the hemostasis valve and the aspiration catheter are configured to receive and route an instrument therethrough.

22. The clot treatment system of claim 17 wherein the hemostasis valve comprises:

a tubular member defining a lumen;

a first filament extending in a first loop around the tubular member;

a second filament extending in a second loop around the tubular member; and

a pair of actuators biased to circumferentially constrict the first loop and the second loop to elastically deform the tubular member to a first position in which the lumen is constricted, wherein at least one the actuators is movable to decrease a level of tension in the first filament and a level of tension in the second filament to permit the tubular member to expand against the first loop and the second loop to a second position in which the lumen of the tubular member is at least partially open.

23. The clot treatment system of claim 22 wherein the actuators each comprise a button.

24. The clot treatment system of claim 22 wherein the first filament includes a first portion operably coupled to a first one of the actuators and a second portion operably coupled to a second one of the actuators, and wherein the second filament includes a first portion operably coupled to the first one of the actuators and a second portion operably coupled to the second one of the actuators.

25. The clot treatment system of claim 22 wherein the first filament is flexible, and wherein the second filament is flexible.

26. The clot treatment system of claim 17 wherein the aspiration catheter has a size of at least 16 French.

27. The clot treatment system of claim 17 wherein the aspiration catheter has a size of at least 20 French.

28. The clot treatment system of claim 17 wherein the aspiration catheter has a size of at least 22 French.

Assignments (2)

Continuity (5)

References Cited (400)

Cited By (7)

US 12,310,608 US 12,364,496 US 12,465,382 US 12,558,112 US 12,558,486 US 12,685,549 US 12,702,538