Systems and methods for embolization of body structures
A device for treatment of a vascular defect within a patient's vasculature includes a self-expanding permeable shell having a proximal end, a distal end, and a longitudinal axis, the shell comprising a plurality of elongate resilient filaments having a braided structure, wherein the filaments are secured at at least one of the proximal end or the distal end of the permeable shell, wherein the permeable shell has a radially constrained elongated state configured for delivery within a microcatheter and has an expanded state with an axially shortened configuration relative to the radially constrained state, the permeable shell having a plurality of openings formed between the braided filaments, wherein the permeable shell in its expanded state comprises a plurality of circumferentially-arrayed lobes.
1 . A device for treatment of a vascular defect, comprising:
a single self-expanding permeable shell comprising a mesh; the self-expanding permeable shell comprising a radially compressed shape and a radially expanded shape;
the radially expanded shape of the self-expanding permeable shell comprising a first plurality of longitudinally-arrayed lobes and each lobe of the first plurality of longitudinally-arrayed lobes extends between a proximal first end of the self-expanding shell and a distal second end of the self-expanding shell; and,
wherein the mesh comprises a plurality of elongated resilient filaments and has a memorized shape which self-expands to form the first plurality of longitudinally-arrayed lobes.
2 . The device of claim 1 , further comprising a plurality of longitudinally-extending channels positioned between each of the first plurality of longitudinally-arrayed lobes.
3 . The device of claim 2 , wherein the plurality of longitudinally-extending channels only extend partially between the first end and the second end.
4 . The device of claim 2 , wherein the plurality of longitudinally-extending channels are folds or pleats.
5 . The device of claim 1 , wherein each of the first plurality of longitudinally-arrayed lobes comprise a first side having a first radius of curvature, a second side having a second radius of curvature and a central portion between the first side and the second side comprising a third radius of curvature; wherein the third radius of curvature is greater than each of the first radius of curvature and the second radius of curvature.
6 . The device of claim 1 , wherein the self-expanding permeable shell further comprises a circumferentially-extending channel.
7 . The device of claim 1 , wherein the first plurality of longitudinally-arrayed lobes are evenly distributed around a longitudinal axis of the self-expanded permeable shell.
8 . The device of claim 1 , wherein the plurality of elongated resilient filaments is secured together at the first end of the self-expanding shell.
9 . The device of claim 1 , wherein the radially expanded shape of the permeable shell comprises a major diameter D, and wherein each of the first plurality of longitudinally-arrayed lobes have a radius of curvature r, wherein r<D/2.
10 . A device for treatment of a vascular defect, comprising:
a mesh formed of a plurality of filaments; the mesh having a radially constrained shape and a radially expanded shape;
a first plurality of lobes formed from the mesh and that are each lobe of the first plurality of lobes is longitudinally arrayed between a proximal first end and a distal second end of the radially expanded shape of a single permeable shell;
wherein the mesh has a memorized shape which self-expands to form the first plurality of lobes.
11 . The device of claim 10 , further comprising a continuous ring indented into the mesh and extending 360 degrees around a longitudinal axis of the radially expanded shape.
12 . The device of claim 11 , wherein the continuous ring has a substantially semi-circular cross-section or a substantially triangular cross-section.
13 . The device of claim 10 , wherein each of the first plurality of lobes comprise a first side having a first radius of curvature, a second side having a second radius of curvature and a central portion between the first side and the second side comprising a third radius of curvature; wherein the third radius of curvature is greater than each of the first radius of curvature and the second radius of curvature.
14 . The device of claim 10 , further comprising a plurality of longitudinal channels located between adjacent lobes of the first plurality of lobes.
15 . The device of claim 14 , wherein the plurality of longitudinal channels are folds or pleats.
16 . The device of claim 10 , wherein the mesh comprises drawn filled tubes.
17 . The device of claim 10 , wherein the mesh is composed of three or more groups of filaments, the filaments of each group having a different outer diameter or material composition from each other.
18 . The device of claim 10 , wherein the first end of the radially expanded shape of the mesh is closed and indented.
19 . The device of claim 18 , wherein the second end of the radially expanded shape of the mesh is closed and indented.
20 . A device for treatment of a vascular defect, comprising:
a mesh means for self-expanding from a radially compressed position to a radially expanded memorized shape having a plurality of lobes formed from the mesh and each lobe of the plurality of lobes is longitudinally arrayed between a proximal first end and a distal second end of the radially expanded memorized shape of a single permeable shell.