STROKE REHABILITATION THERAPY PREDICTIVE ANALYSIS
Methods and systems for assessing a stroke rehabilitation outcome of a subject include a home-based brain-controlled interface (BCI) apparatus and a computer processor in communication with the BCI apparatus. The BCI apparatus has i) a portable brain signal acquisition headset that acquires a brain signal from a subject; ii) an orthosis device having a body part interface configured to be coupled to a body part of the subject and a plurality of sensors that generate force data and movement data; and iii) a BCI component that receives the brain signal from the brain signal acquisition headset. The BCI component is capable of controlling the orthosis device. The computer processor performs instructions to process input data to output a rehabilitation outcome prediction for the subject, where the input data includes the brain signal, the force data, the movement data, and background information about the subject.
1 . A system for assessing a stroke rehabilitation outcome of a subject, the system comprising:
a) a home-based brain-controlled interface (BCI) apparatus having:
i) a portable brain signal acquisition headset that acquires a brain signal from the subject;
ii) an orthosis device having a body part interface configured to be coupled to a body part of the subject, and having a plurality of sensors that generate force data and movement data;
iii) a BCI component that receives the brain signal from the brain signal acquisition headset, wherein the BCI component is capable of controlling the orthosis device; and
b) a computer processor in communication with the BCI apparatus, the computer processor performing instructions to process input data to output a rehabilitation outcome prediction for the subject, wherein the input data includes the brain signal, the force data, the movement data, and background information about the subject.
2 . The system of claim 1 , wherein the BCI apparatus further comprises:
iv) a control system configured to operate the orthosis device in:
a BCI mode in which the orthosis device operates to move or assist in a movement of the body part based on an intention of the subject determined from an analysis of the brain signal;
a continuous passive mode in which the orthosis device operates to move the body part with no volition from the subject; and
a volitional mode in which the orthosis device first allows the subject to move or attempt to move the body part in a predefined motion and then operates to move or assist in the predefined motion of the body part.
3 . The system of claim 2 , wherein the input data comprises a somato-sensory evoked potential (SSEP), wherein the computer processor determines the SSEP from:
the brain signal acquired as a result of a BCI motor-generated movement from the continuous passive mode; and
the force data measured by a force sensor in the plurality of sensors during the BCI motor-generated movement.
4 . The system of claim 1 , wherein:
the plurality of sensors comprises an accelerometer or a gyroscope; and
the movement data includes acceleration data from the accelerometer or gyroscope data from the gyroscope.
5 . The system of claim 1 , wherein:
the orthosis device comprises a motor-actuated assembly that actuates the body part interface to move the body part;
the plurality of sensors comprises a force sensor that generates the force data; and
the force data includes forces applied between the body part interface and the motor-actuated assembly.
6 . The system of claim 1 , wherein the background information includes demographics and socio-economic information of the subject.
7 . The system of claim 1 , wherein the background information includes a medical history of the subject, the medical history including stroke lesion characteristics and biometrics.
8 . The system of claim 7 , wherein the instructions to process the input data comprise application of a weighting factor based on a severity level of the stroke lesion characteristics.
9 . The system of claim 1 , wherein the instructions to process the input data comprise calculation of a weighting factor for one or more of the input data based on the background information.
10 . The system of claim 1 , wherein the instructions to process the input data comprise application of a weighting factor based on a strength of the brain signal.
11 . The system of claim 1 , wherein the instructions to process the input data comprise application of a weighting factor based on a ranking of where the brain signal, the force data, the movement data, or the background information lies within a broader stroke population database.
12 . The system of claim 1 , further comprising an environmental sensor or a biometric sensor, wherein the input data includes data from the environmental sensor or the biometric sensor.
13 . The system of claim 1 , wherein the input data further includes imagery assessments of the subject and non-BCI functional assessments.
14 . The system of claim 1 , wherein the rehabilitation outcome prediction comprises a compatibility of the subject with the BCI apparatus, or a rehabilitation response rate of the subject using the BCI apparatus.
15 . The system of claim 1 , wherein the instructions comprise outputting a modification to a rehabilitation program used by the subject, based on the rehabilitation outcome prediction.
16 . The system of claim 1 , wherein the instructions comprise outputting a categorization of a rehabilitation status of the subject.
17 . A method for assessing a stroke rehabilitation outcome of a subject, the method comprising:
a) collecting a brain signal, force data and movement data from a home-based brain-controlled interface (BCI) apparatus; and
b) processing input data, using a computer processor that performs instructions for the processing, wherein the input data comprises background information about the subject along with the brain signal, the force data and the movement data to output a rehabilitation outcome prediction for the subject;
wherein the home-based BCI apparatus includes:
i) a portable brain signal acquisition headset that acquires the brain signal;
ii) an orthosis device having a body part interface configured to be coupled to a body part of the subject, and having a plurality of sensors that generate the force data and the movement data; and
iii) a BCI component that receives the brain signal from the brain signal acquisition headset, wherein the BCI component is capable of controlling of the orthosis device.
18 . The method of claim 17 , wherein the BCI apparatus further comprises:
iv) a control system configured to operate the orthosis device in:
a BCI mode in which the orthosis device operates to move or assist in a movement of the body part based on an intention of the subject determined from an analysis of the brain signal;
a continuous passive mode in which the orthosis device operates to move the body part with no volition from the subject; and
a volitional mode in which the orthosis device first allows the subject to move or attempt to move the body part in a predefined motion and then operates to move or assist in the predefined motion of the body part.
19 . The method of claim 18 , further comprising determining a somato-sensory evoked potential (SSEP), wherein the input data comprises the SSEP, and wherein determining the SSEP comprises:
measuring the brain signal as a result of a BCI motor-generated movement in the continuous passive mode; and
using a force sensor in the plurality of sensors to measure the force data during the BCI motor-generated movement.
20 . The method of claim 17 , wherein the background information includes demographics and socio-economic information of the subject.
21 . The method of claim 17 , wherein the background information includes a medical history of the subject, the medical history including stroke lesion characteristics and biometrics.
22 . The method of claim 21 , wherein processing the input data comprises applying a weighting factor based on a severity level of the stroke lesion characteristics.
23 . The method of claim 17 , wherein processing the input data comprises calculating a weighting factor for one or more of the input data based on the background information.
24 . The method of claim 17 , wherein the instructions to process the input data comprise applying a weighting factor based on a strength of the brain signal.
25 . The method of claim 17 , further comprising determining a weighting factor based on a ranking of where the brain signal, the force data, the movement data, or the background information lies within a broader stroke population database.
26 . The method of claim 17 , wherein the input data further includes imagery assessments of the subject and non-BCI functional assessments.
27 . The method of claim 17 , wherein the rehabilitation outcome prediction comprises a compatibility of the subject with the BCI apparatus, or a rehabilitation response rate of the subject using the BCI apparatus.
28 . The method of claim 17 , further comprising outputting a modification to a rehabilitation program used by the subject, based on the rehabilitation outcome prediction.
29 . The method of claim 17 , further comprising outputting a categorization of a rehabilitation status of the subject.
30 . The method of claim 17 , further comprising:
repeating the collecting to collect updated brain signals, updated force data and updated movement data from the home-based BCI apparatus; and
revising instructions for processing the input data based on the updated brain signals, the updated force data and the updated movement data.