Bioinformatics Systems, Apparatuses, and Methods Executed on an Integrated Circuit Processing Platform
A system, method and apparatus for executing a bioinformatics analysis on genetic sequence data includes an integrated circuit formed of a set of hardwired digital logic circuits that are interconnected by physical electrical interconnects. One of the physical electrical interconnects forms an input to the integrated circuit that may be connected with an electronic data source for receiving reads of genomic data. The hardwired digital logic circuits may be arranged as a set of processing engines, each processing engine being formed of a subset of the hardwired digital logic circuits to perform one or more steps in the bioinformatics analysis on the reads of genomic data. Each subset of the hardwired digital logic circuits may be formed in a wired configuration to perform the one or more steps in the bioinformatics analysis.
1 . A genomics analysis platform for executing a sequence analysis pipeline, the genomics analysis platform comprising:
one or more of a first integrated circuit, each first integrated circuit being responsive to one or more software algorithms that are configured to instruct the first integrated circuit to perform a first set of genomic processing steps of the sequence analysis pipeline, each first integrated circuit having a first set of physical electronic interconnects;
one or more of a second integrated circuit, each second integrated circuit having a second set of physical electronic interconnects to connect with at least one first integrated circuit via a portion of the first set of physical electronic interconnects using a point-to-point interconnect protocol, each second integrated circuit being configured by firmware to arrange a set of hardwired digital logic circuits that are interconnected by a plurality of physical interconnects to perform a second set of genomic processing steps of the sequence analysis pipeline, the set of hardwired digital logic circuits being arranged as a set of processing engines to perform the second set of genomic processing steps; and
a shared memory electronically connected with each first integrated circuit via at least a portion of the first set of physical electronic interconnects, the shared memory being accessible by each first integrated circuit and each second integrated circuit to provide genetic sequence data and to store result data from the genomic processing steps performed on the genetic sequence data by each first integrated circuit and each second integrated circuit.