HUMIDITY CONTROL USING WATER FLOW
Systems and methods are provided herein for control of humidification of a breathing gas for respiratory therapy. Control of humidification is provided by inverse adjustment of liquid flowrate, and this technique allows the user to adjust humidity independent of other therapy parameters such as gas temperature and gas flowrate.
1 . A method for adjusting humidity of breathing gas supplied by a respiratory therapy system, the system comprising:
a gas supply module configured to supply a flow of breathing gas;
a liquid supply module configured to supply a flow of liquid; and
a vapor transfer module configured to receive the flows of breathing gas and liquid, humidify the breathing gas, and output heated and humidified breathing gas;
the method comprising:
supplying the flow of breathing gas from the gas supply module to the vapor transfer module;
supplying the flow of liquid from the liquid supply module to the vapor transfer module at a first liquid flowrate;
outputting the heated and humidified breathing gas from the vapor transfer module at a first gas temperature, a first gas flowrate, and a first humidity;
adjusting the first liquid flowrate to a second liquid flowrate; and
outputting the heated and humidified gas from the vapor transfer module at about the first gas temperature, about the first gas flowrate, and a second humidity;
wherein a difference between the first humidity and second humidity is inversely proportional to the adjustment of the first liquid flowrate to the second liquid flowrate.
2 . The method of claim 1 , wherein the liquid supply module comprises:
a heater configured to heat the liquid;
a pump configured to circulate the liquid; and
a reservoir configured to hold liquid and having an outlet port and a return port, the return port being in fluid communication with the vapor transfer module and configured to convey liquid from the vapor transfer module to the reservoir.
3 . The method of any of claims 1-2 , wherein the vapor transfer module comprises:
a vapor transfer cartridge; and
a delivery tube.
4 . The method of claim 3 , wherein the vapor transfer cartridge comprises:
a gas inlet;
a gas outlet;
a liquid inlet; and
a liquid outlet, wherein the gas inlet receives the flow of breathing gas from the gas supply module, and the gas outlet outputs the heated and humidified breathing gas.
5 . The method of claim 4 , wherein the delivery tube comprises:
a gas lumen; and
a liquid lumen at least partially surrounding the gas lumen, the gas lumen being in fluid communication with the gas outlet of the vapor transfer cartridge so as to receive the heated and humidified breathing gas from the gas outlet of the vapor transfer cartridge.
6 . The method of claim 5 , wherein the delivery tube comprises:
a first end; and
a second end, wherein the gas lumen receives the heated and humidified breathing gas at the first end and conveys the heated and humidified gas to the second end.
7 . The method of claim 6 , wherein the liquid lumen comprises:
a first channel; and
a second channel, the first channel configured to convey liquid from the first end to the second end, and the second channel is in fluid communication with the first channel at the second end and configured to convey the liquid from the second end to the first end.
8 . The method of claim 7 , wherein the second channel at the first end is in fluid communication with the liquid inlet of the vapor transfer cartridge, and the liquid inlet receives liquid from the second channel.
9 . The method of claim 7 , wherein the delivery tube further comprises a first temperature sensor disposed at an inlet of the first channel and a second temperature sensor disposed at an outlet of the second channel.
10 . The method of claim 9 , wherein the first temperature sensor and second temperature sensor each measure a temperature, and a temperature difference between the measured temperatures is less than 5% of the first gas temperature.
11 . The method of claim 10 , wherein the temperature difference is less than 1° C.
12 . The method of any of claims 5-11 , wherein the vapor transfer module and the liquid supply module define a liquid circulation loop, whereby liquid flows from the reservoir, to the heater, to the liquid lumen of the delivery tube, to the liquid inlet of the vapor transfer cartridge, through the vapor transfer cartridge, and to the reservoir via the return port.
13 . The method of any of claims 4-12 , wherein the liquid outlet of the vapor transfer cartridge is configured to convey liquid from the vapor transfer cartridge to the reservoir via the return port.
14 . The method of any of claims 4-13 , wherein the gas inlet and liquid outlet are disposed at a first end of the vapor transfer cartridge, and the gas outlet and liquid inlet are disposed at a second end of the vapor transfer cartridge, such that the liquid and gas flow through the vapor transfer cartridge in opposite directions.
15 . The method of any of claims 4-14 , wherein a liquid temperature at the liquid inlet is held constant before and after the adjusting step.
16 . The method of any of claims 3-15 , wherein the system further comprises a nasal cannula coupled to the delivery tube and configured to convey the heated and humidified breathing gas to nares of a patient.
17 . The method of any of claims 3-16 , wherein the vapor transfer cartridge comprises a plurality of hollow fibers.
18 . The method of any of claims 3-16 , wherein the vapor transfer cartridge comprises a pleated membrane or a flat sheet membrane.
19 . The method of any of claims 3-16 , wherein the vapor transfer cartridge comprises a heated wick.
20 . The method of any of claims 1-19 , wherein the gas supply module comprises a blower configured to output the flow of breathing gas.
21 . The method of any of claims 1-20 , wherein the system further comprises:
a controller operatively coupled to the gas supply module and the liquid supply module and configured to adjust at least one of a gas temperature setpoint, a gas flowrate setpoint, a liquid flowrate setpoint, or a liquid temperature setpoint.
22 . The method of any of claims 1-21 , wherein the second liquid flowrate is less than the first liquid flowrate, and the second humidity is greater than the first humidity.
23 . The method of any of claims 1-21 , wherein the second liquid flowrate is greater than the first liquid flowrate, and the second humidity is less than the first humidity.
24 . The method of any of claims 1-23 , wherein the first gas temperature is 30 to 40° C.
25 . The method of any of claims 1-24 , wherein the first gas flowrate is 5 to 45 L/min.
26 . The method of any of claims 1-25 , wherein at least one of the first humidity or the second humidity is 25-45 mg/L.