SOFT TISSUE REPAIR ALLOGRAFTS AND METHODS FOR PREPARING SAME
Allografts for soft tissue repair, including breast reconstruction and other plastic surgery procedures, are disclosed. In one embodiment, two allografts are produced from the same decellularized dermal tissue, each of which consists essentially of reticular dermis, and comprises a collagen matrix having substantially uniform density and porosity.
1 . An allograft dermal tissue form for use in surgical procedures, comprising a portion of dermal tissue having a first exposed surface formed by a first cut and a second exposed surface formed by a second cut opposite said first exposed surface, said portion of dermal tissue constituting a collagen matrix having substantially uniform density and porosity between said first exposed surface and said second exposed surface.
2 . The allograft dermal tissue form of claim 1 , wherein said portion of dermal tissue includes a portion of a papillary dermis and at least a portion of a reticular dermis.
3 . The allograft dermal tissue form of claim 2 , wherein said portion of said papillary dermis is a lower portion distal an epidermis and adjacent the reticular dermis, said lower portion being structurally different from an upper portion of said papillary dermis proximate the epidermis.
4 . The allograft dermal tissue form of claim 1 , wherein said portion of dermal tissue is in sheet form.
5 . The allograft dermal tissue form of claim 1 , wherein said portion of dermal tissue is in particulate form.
6 . The allograft dermal tissue form of claim 1 , wherein said portion of dermal tissue is perforated, and thereby in mesh form.
7 . The allograft dermal tissue form of claim 1 , further comprising cells.
8 . The allograft dermal tissue form of claim 7 , wherein said cells include one or more of the group consisting of stem cells, fibroblasts, osteoblasts, myoblasts and keratinocytes.
9 . The allograft dermal tissue form of claim 1 , further comprising one or more biological substances.
10 . The allograft dermal tissue form of claim 9 , wherein said one or more biological substances are selected from the group consisting of platelet-rich plasma, bone marrow aspirate, demineralized bone particles or fibers other allograft tissue forms, and amnion tissue.
11 . The allograft dermal tissue form of claim 1 , further comprising reinforcing elements.
12 . The allograft dermal tissue form of claim 11 , wherein said reinforcing elements are absorbable fibers.
13 . The allograft dermal tissue form of claim 11 , wherein said reinforcing elements are non-absorbable fibers.