SYSTEM AND METHOD OF TREATING CARDIOVASCULAR IMPAIRMENT
A method for implanting a device into a heart of a mammal can include a fluid conduit passing from the atrium into the aorta. The fluid conduit may also include a pump and sensors in the atrium for feedback to a controller for operation of the pump. An outflow portion of the fluid contact may include a diffuser or flow-directing hood for managing type and direction of flow into the aorta.
1 . A method of implanting a device into a heart of a mammal, comprising:
inserting a fluid conduit having an inflow portion and an outflow portion into a cardiovascular system of the mammal, wherein the inflow portion is located within an atrium of the heart of the mammal and the outflow portion is located within an aorta of the cardiovascular system of the mammal, and the fluid conduit passing from the atrium into the aorta.
2 . The method of claim 1 , wherein the atrium is a left atrium.
3 . The method of claim 1 , wherein the atrium is a left atrium and the outflow portion is into a descending portion of the aorta.
4 . The method of claim 1 , wherein the outflow portion includes a diffuser or a flow-directing hood.
5 . The method of claim 1 , wherein the fluid conduit includes a structure to prevent contact of a body of the fluid conduit with a wall of the atrium to minimize thrombus formation and ingestion of thrombus into the fluid conduit.
6 . The method of claim 1 , wherein the fluid conduit is configured to supply a helical flow of fluid from the outflow portion.
7 . The method of claim 1 , wherein the fluid conduit is configured to supply a flow of fluid from the outflow portion having a velocity of less than 3.0 m/s.
8 . The method of claim 1 , wherein the fluid conduit is configured to supply a flow of fluid from the outflow portion having a wall shear stress of less than 4500 dynes/cm 2 .
9 . The method of claim 1 , wherein the atrium is a left atrium and further comprising maintaining pressure in the left atrium between 18 and 25 mm Hg to assist the mammal with HFpEF.
10 . The method of claim 1 , wherein the atrium is a left atrium and further comprising reducing pressure in the left atrium to between 10 and 15 mm Hg to assist the mammal with HFrEF.
11 . The method of claim 1 , further comprising providing a signal from a sensor in a left atrium indicative of a pressure in the left atrium as feedback to a controller for the fluid conduit.
12 . The method of claim 1 , wherein the fluid conduit includes a pump.
13 . A system for improving blood flow in a mammal, comprising:
a fluid conduit having an atrium inflow portion and an aorta outflow portion;
a pump disposed in the fluid conduit; and
a controller configured to operate the pump for regulating blood flow through the fluid conduit from the atrium to the aorta.
14 . The system of claim 13 , wherein the atrium inflow portion is in a left atrium and the aorta outflow portion is in a descending portion of the aorta.
15 . The system of claim 13 , wherein the controller regulates rate of blood flow through the conduit from the atrium to the aorta or fluid velocity through the conduit from the atrium to the aorta.
16 . The system of claim 13 , wherein the aorta outflow portion includes a diffuser.
17 . The system of claim 13 , wherein the aorta outflow portion includes a flow-directing hood.
18 . The system of claim 13 , wherein the fluid conduit includes a cage to prevent contact of a body of the fluid conduit with a wall of the atrium to minimize thrombus formation and ingestion of thrombus into the pump.
19 . The system of claim 13 , wherein the fluid conduit is configured to supply a helical flow of fluid from the aorta outflow portion.
20 . The system of claim 13 , further comprising a pressure sensor coupled to the atrium inflow portion, wherein the pressure sensor is configured to provide a pressure measurement in the atrium as feedback to the controller.