CRYSTALLINE FORMS OF PENTAAZA MACROCYCLIC RING COMPLEX
The present invention provides crystalline forms of a pentaaza macrocyclic ring complex according to the following formula: Also provided are pharmaceutical compositions that include the provided crystalline forms and methods of using the provided crystalline forms and pharmaceutical compositions for the treatment of disease states.
1 . A Form E anhydrate crystalline form of GC4711 according to the following formula:
having one or more characteristic XRPD (X-Ray Powder Diffraction) peaks as shown in FIG. 10 .
2 . A pharmaceutical composition comprising the Form E anhydrate crystalline form of GC4711 according to claim 1 .
3 . A method of treating cancer comprising administering a composition of claim 2 and one or more pharmaceutically acceptable excipients to a patient in need thereof.
4 . A method of treating an inflammatory condition comprising administering a composition of claim 2 and one or more pharmaceutically acceptable excipients to a patient in need thereof.
5 . The method of claim 4 , wherein the inflammatory condition is oral mucositis.