IP Library Granted Patent US 12,318,218
Granted Patent B1
US 12,318,218 · App. 18/649,589 · Granted Jun 3, 2025

Virtual health coach for facilitating dynamic dosage titration

Inventors: Nikhil Roy (Sunnyvale, CA); Miguel Angelo Drumond (Oakland, CA)
Assignee: Verily Life Sciences LLC
A61B5/486A61B5/0022A61B5/0077A61B5/1112A61B5/1118A61B5/14532A61B5/4839G06F40/30G06V10/768G16H20/10G16H20/17H04L51/02G06Q50/01H04W88/02
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Quick Facts
Patent No.
US 12,318,218
App. No.
18/649,589
Granted
Jun 3, 2025
Kind
B1
Abstract

A computer-implemented method improves efficacy of diabetes self-management to obtain a measurement message and/or contextual activity information used to determine a suitable insulin dosage to treat a patient. The method includes simulating a health coach in a natural conversation to obtain a measurement of the patient's blood-glucose level, processing the measured blood-glucose level with a personalized insulin titration algorithm to determine an insulin dosage recommendation, and generating an electronic signal configured to cause a corresponding action to be performed by a computing device.

Claims (56)

1. A method comprising:

launching a computer program that autonomously facilitates a conversation in which dialogue is exchanged with an individual to whom insulin is delivered,

wherein the conversation includes—

a first message, from the computer program, that requests the individual specify a value for a blood glucose level, and

a second message, from the individual, that specifies the value for the blood glucose level;

determining a dosage to treat the individual based on the value for the blood glucose level that is specified in the second message;

adjusting the dosage based on information regarding context of the individual; and

effecting delivery of an amount of insulin based on the dosage, as adjusted to account for the context of the individual.

2. The method of claim 1 , wherein said launching is performed in accordance with a schedule that is set by a healthcare provider of the individual.

3. The method of claim 1 , wherein said launching is performed in response to a determination that the individual has completed a predetermined activity.

4. The method of claim 3 , further comprising:

receiving, via a wireless communication channel, data from a computing device that is located proximate to the individual; and

determining that the individual has completed the predetermined activity based on an analysis of the data.

5. The method of claim 1 , wherein the information regarding the context of the individual is derived from the conversation.

6. A method comprising:

initiating a computer program that facilitates a conversation in which dialogue is exchanged with an individual to whom insulin is delivered,

wherein the conversation includes—

a first message, from the computer program, that requests the individual specify a value of a blood glucose level, and

a second message, from the individual, that specifies the value for the blood glucose level;

determining a dosage for treating the individual based on the value for the blood glucose level specified in the second message; and

effecting delivery of a suitable amount of insulin based on the dosage.

7. The method of claim 6 , further comprising:

deriving information regarding a physical activity performed by the individual based on an analysis of the conversation; and

adjusting the dosage based on the information, so as to account for the physical activity performed by the individual.

8. The method of claim 6 , further comprising:

deriving information regarding a food or a beverage consumed by the individual based on an analysis of the conversation; and

adjusting the dosage based on the information, so as to account for the food or the beverage consumed by the individual.

9. The method of claim 6 , further comprising:

deriving information regarding a medication administered by the individual based on an analysis of the conversation; and

adjusting the dosage based on the information, so as to account for the medication administered by the individual.

10. The method of claim 6 , further comprising:

acquiring, from a source external to the computer program, information regarding an external factor that affects, or is experienced by, the individual; and

adjusting the dosage based on the information, so as to account for the external factor.

11. The method of claim 10 , wherein the external factor is daylight duration, average temperature, season, geographical altitude, or pollution level.

12. The method of claim 6 , further comprising:

acquiring, from a source external to the computer program, information regarding a characteristic of the individual; and

adjusting the dosage based on the information, so as to account for the characteristic.

13. The method of claim 12 , wherein the characteristic is age, gender, genotype, or phenotype.

14. The method of claim 6 , wherein the dosage is a basal insulin dosage or a bolus insulin dosage.

15. The method of claim 6 , wherein the computer program operates in accordance with a set of rules, at least one of which is customized for the individual to manage diabetes in a personalized manner.

16. A non-transitory medium with instructions that, when executed by a processor of a computing device, cause the computing device to perform operations comprising:

initiating a computer program that facilitates a conversation in which dialogue is exchanged with an individual to whom medication is delivered to manage a disease,

wherein the conversation includes—

a first message, from the computer program, that requests the individual specify a value for a physiological characteristic, and

a second message, from the individual, that specifies the value for the physiological characteristic;

deriving information regarding a physical activity that is performed by the individual based on an analysis of the conversation;

determining a dosage to treat the individual based on the value for the physiological characteristic specified in the second message;

adjusting the dosage based on the information, so as to account for the physical activity of the individual; and

effecting delivery of an amount of the medication based on the adjusted dosage.

17. The non-transitory medium of claim 16 , wherein the operations further comprise:

posting, to an interface, the adjusted dosage for review by the individual.

18. The non-transitory medium of claim 16 , wherein said effecting comprises:

generating an electronic signal that is configured to cause an insulin delivery device to administer insulin to the individual in accordance with the adjusted dosage.

19. The non-transitory medium of claim 18 , wherein the insulin delivery device is configured to administer the insulin during the conversation.

20. The non-transitory medium of claim 18 , wherein said effecting further comprises:

transmitting the electronic signal to the insulin delivery device via a network.

Assignments (2)
CHANGE OF NAME Recorded Apr 21, 2026
From: VERILY LIFE SCIENCES LLC
To: VERILY HEALTH INC.
Reel/Frame 075477/0981 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 29, 2024
From: ROY, NIKHIL; DRUMOND, MIGUEL ANGELO
To: VERILY LIFE SCIENCES LLC
Reel/Frame 067258/0683 →
Continuity (3)
Continuation 17933540 · Sep 20, 2022
Continuation 16172180 · Oct 26, 2018
Provisional Application 62578150 · Oct 27, 2017
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