ANHYDROUS BARRIER AND ANTIOXIDANT COMPOSITIONS
Topical formulations of an anhydrous liquid, composed of primary and secondary antioxidants, barrier-repairing agent(s), and hydrocarbon compound(s). The formulations are storage stable for an extended period of time without significant degradation as measured by a change in texture, appearance or odor, and have desirable physical properties. Topical compositions of this disclosure find use in treating or preventing a variety of cosmetic and/or dermatological conditions.
1 . A storage stable, topical, anhydrous, liquid composition comprising:
a. 0.5% to 3% by weight of a primary oil-soluble antioxidant comprising bakuchiol, Curcuma longa extract, or a combination thereof;
b. 0.5% to 5% by weight of a secondary oil-soluble antioxidant selected from: tocopherol, bis-ethylhexyl hydroxydimethoxy benzylmalonate, dimethylmethoxy chromanol, hexylresorcinol, and a combination thereof;
c. 4% to 30% by weight of a barrier repairing agent selected from: lanolin, cholesterol, a cholesterol derivative, lanosterol, a lanosterol derivative, a polyglyceryl fatty acid ester, and a combination thereof;
d. 4% to 95% by weight of a hydrocarbon-based emollient selected from: a linear higher alkane of animal, mineral or synthetic origin, a branched higher alkane of animal, mineral, or synthetic origin, and a combination thereof; and
e. Less than 1% by weight water.
2 . The storage stable, topical, anhydrous, liquid composition of claim 1 , wherein the primary oil-soluble antioxidant comprises about 1% by weight bakuchiol.
3 . The storage stable, topical, anhydrous liquid composition of claim 1 , wherein the primary oil-soluble antioxidant comprises about 0.5% by weight of Curcuma longa root extract.
4 . The storage stable, topical anhydrous liquid composition of claim 1 , wherein the secondary oil-soluble antioxidant comprises about 1% by weight tocopherol.
5 . The storage stable, topical anhydrous liquid composition of claim 1 , wherein the secondary oil-soluble antioxidant comprises about 0.5% to 2% by weight of bis-ethylhexyl hydroxydimethoxy benzylmalonate.
6 . The storage stable, topical, composition of claim 1 , wherein the barrier repairing agent comprises about 20% by weight of a mixture of C 10 -C 30 Cholesteryl esters and C 10 -C 30 lanosteryl esters.
7 . The storage stable, topical, composition of claim 1 , wherein the hydrocarbon-based emollient does not comprise a hydrocarbon-based oil of plant origin.
8 . The storage stable, topical, composition of claim 7 , wherein the hydrocarbon-based emollient does not comprise a triglyceride.
9 . The storage stable, topical composition of claim 8 , wherein the hydrocarbon-based emollient has a boiling point ranging from 150° C. to 380° C.
10 . The storage stable, topical composition of claim 9 , wherein the hydrocarbon-based emollient has a boiling point ranging from 150° C. to 300° C.
11 . The storage stable, topical composition of claim 10 , wherein the hydrocarbon-based emollient has a boiling point ranging from 165 to 200° C.