System and method for outcome tracking and analysis
Provided are systems and methods for capturing outcome information associated with various cancer treatments. The system facilitates capture and analysis of cancer treatment information and associated outcome information. The treatment and outcome information can include genomic analysis and information on treatment of different cancers. The system can store and analyze any one or more of: tumor type, genomic alterations (e.g., genes and associated alterations, gene sequence mutations, alterations, amplifications, deletions, etc.), and treatment data (including, for example, treatments targeted to specific genes and/or genomic alterations). Users of the outcome system can supply and use the treatment and outcome information to facilitate diagnosis and therapy decisions. User interfaces within the system can be configured to allow users to easily locate outcome information associated with particular treatments of tumors having certain genomic alterations.
1 . An electronic device, comprising:
a display;
one or more processors;
a memory; and
one or more programs, wherein the one or more programs are stored in the memory and configured to be executed by the one or more processors, the one or more programs including instructions for:
receiving genomic testing results of a patient, wherein the genomic testing result comprises a first genomic alteration and a second genomic alteration of the patient;
identifying by the one or more processors, for the first genomic alteration, a first set of actionable information;
identifying by the one or more processors, for the second genomic alteration, a second set of actionable information;
causing a user interface associated with the patient to display on the display, the user interface comprising a first area comprising:
a first data structure indicative of the first set of actionable information, and
a second data structure indicative of the second set of actionable information,
wherein the first data structure and the second data structure are automatically ranked based on an actionability metric;
receiving a user selection on the first data structure; and
responsive to receiving the user selection, causing the user interface to transition to a display of a second area,
wherein the second area comprises a plurality of extendable drawers, and
wherein the plurality of extendable drawers correspond to the first set of actionable information and the second set of actionable information.
2 . The electronic device of claim 1 , wherein identifying the first set of actionable information comprises: identifying one or more therapies associated with the first genomic alteration, one or more clinical trials associated with the first genomic alteration, one or more references associated with the first genomic alteration, or any combination thereof.
3 . The electronic device of claim 2 , wherein the first data structure comprises a first tag indicative of a count of the one or more therapies and/or a second tag indicative of a count of the one or more clinical trials.
4 . The electronic device of claim 3 , wherein the user selection on the first data structure comprises a user selection of one of the first tag and the second tag.
5 . The electronic device of claim 1 , wherein the plurality of drawers comprises:
a first drawer corresponding to a therapy category;
a second drawer corresponding to a clinical trial category;
a third drawer corresponding to a genomic interpretation category; and
a fourth drawer corresponding to a reference category.
6 . The electronic device of claim 5 , wherein the first drawer displays one or more of:
an identification of a therapy;
whether the therapy is approved for a tumor type found in the patient; and
an indication of whether the therapy is approved for other tumor types.
7 . The electronic device of claim 5 , wherein the second drawer displays one or more of:
a) an identifier for a clinical trial;
b) rationale for the trial;
c) a description of the trial;
d) a geographic location of trial;
e) an identification of a target in clinical trial,
wherein one or more of a-e are presented concurrently to the user, without need for leaving the user interface.
8 . The electronic device of claim 5 , wherein the third drawer displays one or more of:
interpretive information of a genomic alteration;
a name of an affected gene; and
a type of the genomic alteration.
9 . The electronic device of claim 5 , wherein the third drawer further displays one or more related therapies, one or more related clinical trials, one or more related references, or any combination thereof.
10 . The electronic device of claim 5 , wherein the fourth drawer displays one or more of:
bibliography of a reference, and
a navigable link to the reference.
11 . The electronic device of claim 1 , wherein the actionability metric specifies a highest level of actionability to therapy information.
12 . The electronic device of claim 11 , wherein the actionability metric specifies a second level of actionability to clinical trial information.
13 . The electronic device of claim 12 , wherein the actionability metric specifies a third level of actionability to reference information.
14 . The electronic device of claim 1 , wherein the actionability metric is at least partially based on FDA approval information.
15 . The electronic device of claim 1 , further comprising displaying a user interface of recent updates to the first set of actionable information or the second set of actionable information.
16 . The electronic device of claim 1 , further comprising:
receiving, from a plurality of databases, information related to the first genomic alteration;
parsing the information related to the first genomic alteration; and
automatically generating interpreted statements based on the information.
17 . The electronic device of claim 16 , wherein the interpreted statements are accessible via the first data structure.
18 . The electronic device of claim 1 , wherein the genomic testing result is related to a cancer of the patient.