IP Library Granted Patent US 12,409,143
Granted Patent B2
US 12,409,143 · App. 18/842,531 · Granted Sep 9, 2025

Softgel capsules and a method for preparing the softgel capsules

Inventors: Haitao Li (St. Petersburg, FL); Qi Fang (St. Petersburg, FL); Karunakar Sukuru (St. Petersburg, FL)
Assignee: R.P. Scherer Technologies, LLC
A61K9/4816A61K9/4833A61K47/02
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Quick Facts
Patent No.
US 12,409,143
App. No.
18/842,531
Granted
Sep 9, 2025
Kind
B2
Abstract

Disclosed herein is a method for preparing a softgel capsule including treating a softgel capsule with a solution including calcium salt, wherein the softgel capsule includes a fill material and a shell composition including pectin.

Claims (20)

1. A method for treating a softgel capsule comprising

applying a treatment solution to a softgel capsule, wherein the treatment solution comprises a calcium salt and a sugar, wherein the softgel capsule comprises a fill material and a shell composition.

2. The method of claim 1 , wherein the calcium salt comprises calcium chloride, calcium citrate, calcium gluconate, calcium lactate or a combination thereof.

3. The method of claim 1 , wherein the solution further comprises hydrochloric acid.

4. The method of claim 1 , wherein the solution further comprises water.

5. The method of claim 1 , wherein the sugar comprises dextrose.

6. The method of claim 1 , wherein the calcium salt is included in an amount of about 1 wt % to about 25 wt %, based on the total weight of the solution.

7. The method of claim 3 , wherein the pH of the solution is less than 3.

8. The method of claim 5 , wherein the dextrose is included in an amount of about 0.1 wt % to about 20 wt %, based on the total weight of the solution.

9. The method of claim 1 , wherein the shell composition comprises a plasticizer, pectin, gellan gum, dextrose, gelatin, or a combination thereof.

10. The method of claim 9 , wherein the plasticizer comprises glycerin, sorbitol, sorbitol sorbitan solution, triacetin, polysorbate, or combinations thereof.

11. The method of claim 9 , wherein the plasticizer comprises glycerin, sorbitol sorbitan solution, or a combination thereof.

12. The method of claim 9 , wherein the plasticizer is sorbitol sorbitan solution.

13. The method of claim 1 , further comprising drying the capsules after treating the capsules.

14. The method of claim 13 , wherein the drying is performed by tumble drying the capsules.

15. The method of claim 13 , wherein the drying occurs for about 5 minutes to about 6 hours.

16. The method of claim 13 , wherein the drying is performed in a drying chamber or a drying tunnel.

17. The method of claim 1 , further comprising adding the softgel capsule to washing treatment equipment, and applying the treatment solution for a time period of about 5 seconds to about 10 minutes.

18. The method of claim 17 , wherein the washing treatment equipment is fully automatic.

19. The method of claim 17 , wherein the washing treatment equipment is jacketed, and the washing equipment is cooled or chilled using an external chiller.

Assignments (1)
SECURITY INTEREST Recorded Dec 19, 2024
From: CATALENT CTS (KANSAS CITY), LLC; REDWOOD BIOSCIENCE, INC.; R.P. SCHERER TECHNOLOGIES, LLC; CATALENT WELLNESS, LLC; CATALENT PHARMA SOLUTIONS, INC.; CATALENT WELLNESS NEW JERSEY, LLC; CATALENT MARYLAND, INC.; CATALENT GREENVILLE, INC.; CATALENT MICRON TECHNOLOGIES, INC.; CATALENT SAN DIEGO, INC.; CATALENT WELLNESS VIRGINIA, LLC; CATALENT USA PACKAGING, LLC; CATALENT PHARMA SOLUTIONS, LLC
To: ARES CAPITAL CORPORATION, AS COLLATERAL AGENT
Reel/Frame 069743/0458 →
Continuity (2)
Provisional Application 63432445 · Dec 14, 2022
Related Publication 20250108012A1 · Apr 3, 2025
References Cited (6)
US 20040013721A1 · Antipov et al. · 2004 [cited by applicant]
US 20100055174A1 · Xie et al. · 2010 [cited by applicant]
US 20170348249A1 · Suñé Negre et al. · 2017 [cited by applicant]
CN 212856926U · 2021 [cited by applicant]
WO 2022104338A1 · 2022 [cited by applicant]
International Search Report and Written Opinion of International Application No. PCT/US2023/083754 mailed Apr. 8, 2024, 11 pgs. [cited by applicant]