IP Library › Granted Patent US 12,296,122
Granted Patent B2
US 12,296,122 · App. 18/917,388 · Granted May 13, 2025

Hybrid devices with dimensions that can be adjusted in vivo and methods of manufacturing thereof

Inventors: Nir Nae (Binyamina, IL); Neal Eigler (Agoura Hills, CA); Lior Rosen (Zikhron Ya'akov, IL); Erez Rozenfeld (Shoham, IL); Werner Hafelfinger (Thousand Oaks, CA); John Wardle (San Clemente, CA); James S. Whiting (Los Angeles, CA)
Assignee: V-Wave Ltd.
A61M27/002A61M2205/0216A61M2205/0266A61M2210/125
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Quick Facts
Patent No.
US 12,296,122
App. No.
18/917,388
Granted
May 13, 2025
Kind
B2
Abstract

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

Claims (37)

1. A hybrid shunt comprising shape-memory material for placement at an atrial septum of a patient's heart, the hybrid shunt comprising:

a neck region configured to be malleable at body temperature;

a first end region configured to be superelastic at body temperature, a distal end of the first end region configured to be permanently fixed to a proximal end of the neck region at a first connection;

a second end region configured to be superelastic at body temperature, a proximal end of the second end region configured to be permanently fixed to with a distal end of the neck region at a second connection; and

a passageway extending through the first end region, the neck region, and the second end region for blood to flow across the atrial septum,

wherein a flow area of the passageway through the neck region is configured to be adjustable in vivo.

2. The hybrid shunt of claim 1 , wherein the first and second end regions are not formed integrally with the neck region.

3. The hybrid shunt of claim 1 , wherein the proximal and distal ends of the neck region comprise a shape configured to interlock with a complementary shape of the distal end of the first end region and the proximal end of the second end region, respectively.

4. The hybrid shunt of claim 3 , wherein the complementary shapes of the proximal and distal ends of the neck region and the distal end of the first end region and the proximal end of the second end region comprise a tab element and a socket element.

5. The hybrid shunt of claim 4 , wherein the tab element is configured to be thermally contracted or the socket element is configured to be thermally expanded such that the tab element fits within the socket element, and wherein, when the tab and socket elements are brought to a same temperature while the tab element is received within the socket element, the tab element and the socket element form a rigid connection.

6. The hybrid shunt of claim 4 , further comprising a retaining ring configured to be disposed over the tab and socket elements when the tab element is fitted within the socket element to maintain a rigid connection between the tab and socket elements.

7. The hybrid shunt of claim 6 , wherein an outer surface of the socket element comprises one or more protrusions, such that the retaining ring maintains the rigid connection between the tab and socket elements via interference fit between the one or more protrusions and an inner surface of the retaining ring.

8. The hybrid shunt of claim 6 , further comprising a physiological sensor disposed on the tab element, such that the physiological sensor is enclosed within the retaining ring when the retaining ring is disposed over the tab and socket elements.

9. The hybrid shunt of claim 1 , wherein the first and second end regions are configured to self-expand from a collapsed delivery state to an expanded deployed state at body temperature.

10. The hybrid shunt of claim 9 , wherein, in the expanded deployed state, a proximal end of the first end region flares outwardly from the distal end of the first end region at the first connection, and a distal end of the second end region flares outwardly from the proximal end of the second end region at the second connection.

11. The hybrid shunt of claim 1 , wherein the distal end of the first end region comprises a plurality of circumferentially spaced apart connectors configured to be permanently fixed to a corresponding plurality of circumferentially spaced apart connectors of the proximal end of the neck region at the first connection, and wherein the proximal end of the second end region comprises a plurality of circumferentially spaced apart connectors configured to be permanently fixed to a corresponding plurality of circumferentially spaced apart connectors of the distal end of the neck region at the second connection.

12. The hybrid shunt of claim 11 , wherein the plurality of circumferentially spaced apart connectors of the distal end of the first end region and the proximal end of the neck region are permanently fixed along a single plane at the first connection, and

wherein the plurality of circumferentially spaced apart connectors of the proximal end of the second end region and the distal end of the neck region are permanently fixed along a single plane at the second connection.

13. The hybrid shunt of claim 11 , wherein the plurality of circumferentially spaced apart connectors of the distal end of the first end region and the proximal end of the neck region are permanently fixed in a staggered manner at the first connection, such that the connections do not all lie in a single plane, and

wherein the plurality of circumferentially spaced apart connectors of the proximal end of the second end region and the distal end of the neck region are permanently fixed in a staggered manner at the second connection, such that the connections do not all lie in a single plane.

14. The hybrid shunt of claim 1 , wherein the neck region comprises NITINOL having an austenitic finish temperature (Af) between 45-60° C.

15. The hybrid shunt of claim 1 , wherein the neck region is configured to be mechanically expandable in vivo such that the passageway expands from a first cross-sectional area to a second cross-sectional area larger than the first cross-sectional area.

16. The hybrid shunt of claim 1 , wherein the neck region is configured to be thermally contractible in vivo.

17. The hybrid shunt of claim 1 , wherein the first and second end regions comprise NITINOL having an austenitic finish temperature (Af) between 5-20° C.

18. The hybrid shunt of claim 1 , wherein the first and second end regions and the neck region comprise a diabolo-shaped shunt.

19. The hybrid shunt of claim 1 , wherein the first and second end regions and the neck region are at least partially encapsulated with a biocompatible material.

20. The hybrid shunt of claim 1 , further comprising a bridge extending from a first outer surface of the first end region to a second outer surface of the second end region, the bridge formed of biocompatible material and configured to engage the patient's atrial septum.

21. The hybrid shunt of claim 20 , wherein the first and second end regions and the neck region are at least partially encapsulated with a biocompatible material integrally formed with the bridge.

22. The hybrid shunt of claim 20 , wherein the first and second end regions and the neck region are at least partially encapsulated with a biocompatible material different from the biocompatible material of the bridge.

23. The hybrid shunt of claim 22 , wherein the biocompatible material of the bridge is configured to permit tissue ingrowth and the biocompatible material of the encapsulation is configured to inhibit tissue ingrowth.

24. The hybrid shunt of claim 22 , wherein the biocompatible material of the bridge has an internodal distance greater than the internodal distance of the biocompatible material of the encapsulation.

25. The hybrid shunt of claim 24 , wherein the internodal distance of the bridge material is selected to permit tissue ingrowth while the internodal distance of the encapsulation material is selected to inhibit tissue ingrowth.

26. The hybrid shunt of claim 24 , wherein the biocompatible material of the bridge and the biocompatible material of the encapsulation are expanded polytetrafluoroethylene (ePTFE).

27. The hybrid shunt of claim 20 , wherein the biocompatible material of the bridge comprises a porosity selected to permit tissue ingrowth.

28. The hybrid shunt of claim 20 , wherein the bridge is configured to remain engaged with the patient's atrial septum when the neck region is contracted.

29. The hybrid shunt of claim 1 , further comprising one or more physiological sensors disposed at the first and/or second connections.

30. The hybrid shunt of claim 29 , wherein the one or more physiological sensors are configured to measure at least one of pressure, flow, velocity, temperature, or pH.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 12, 2025
From: NAE, NIR; EIGLER, NEAL; ROSEN, LIOR; ROZENFELD, EREZ; HAFELFINGER, WERNER; WARDLE, JOHN; WHITING, JAMES S.
To: V-WAVE LTD.
Reel/Frame 070196/0508 →
Continuity (2)
Provisional Application 63591428 · Oct 18, 2023
Related Publication 20250128032A1 · Apr 24, 2025
References Cited (400)
US 744589A · Moore · 1903 [cited by applicant]
US 3852334A · Dusza et al. · 1974 [cited by applicant]
US 3874388A · King et al. · 1975 [cited by applicant]
US 3952334A · Bokros et al. · 1976 [cited by applicant]
US 4364395A · Redmond et al. · 1982 [cited by applicant]
US 4484955A · Hochstein · 1984 [cited by applicant]
US 4601309A · Chang · 1986 [cited by applicant]
US 4617932A · Kornberg · 1986 [cited by applicant]
US 4662355A · Pieronne et al. · 1987 [cited by applicant]
US 4665906A · Jervis · 1987 [cited by applicant]
US 4705507A · Boyles · 1987 [cited by applicant]
US 4836204A · Landymore et al. · 1989 [cited by applicant]
US 4979955A · Smith · 1990 [cited by applicant]
US 4988339A · Vadher · 1991 [cited by applicant]
US 4995857A · Arnold · 1991 [cited by applicant]
US 5035702A · Taheri · 1991 [cited by applicant]
US 5035706A · Giantureo et al. · 1991 [cited by applicant]
US 5037427A · Harada et al. · 1991 [cited by applicant]
US 5089005A · Harada · 1992 [cited by applicant]
US 5108420A · Marks · 1992 [cited by applicant]
US 5186431A · Tamari · 1993 [cited by applicant]
US 5197978A · Hess · 1993 [cited by applicant]
US 5234447A · Kaster et al. · 1993 [cited by applicant]
US 5267940A · Moulder · 1993 [cited by applicant]
US 5290227A · Pasque · 1994 [cited by applicant]
US 5312341A · Turi · 1994 [cited by applicant]
US 5326374A · Ilbawi et al. · 1994 [cited by applicant]
US 5332402A · Teitelbaum · 1994 [cited by applicant]
US 5334217A · Das · 1994 [cited by applicant]
US 5378239A · Termin et al. · 1995 [cited by applicant]
US 5409019A · Wilk · 1995 [cited by applicant]
US 5429144A · Wilk · 1995 [cited by applicant]
US 5479945A · Simon · 1996 [cited by applicant]
US 5500015A · Deac · 1996 [cited by applicant]
US 5531759A · Kensey et al. · 1996 [cited by applicant]
US 5545210A · Hess et al. · 1996 [cited by applicant]
US 5556386A · Todd · 1996 [cited by applicant]
US 5578008A · Hara · 1996 [cited by applicant]
US 5584803A · Stevens et al. · 1996 [cited by applicant]
US 5597377A · Aldea · 1997 [cited by applicant]
US 5645559A · Hachtman et al. · 1997 [cited by applicant]
US 5655548A · Nelson et al. · 1997 [cited by applicant]
US 5662711A · Douglas · 1997 [cited by applicant]
US 5702412A · Popov et al. · 1997 [cited by applicant]
US 5725552A · Kotula et al. · 1998 [cited by applicant]
US 5741324A · Glastra · 1998 [cited by applicant]
US 5749880A · Banas et al. · 1998 [cited by applicant]
US 5779716A · Cano et al. · 1998 [cited by applicant]
US 5795307A · Krueger · 1998 [cited by applicant]
US 5810836A · Hussein et al. · 1998 [cited by applicant]
US 5824062A · Patke et al. · 1998 [cited by applicant]
US 5824071A · Nelson et al. · 1998 [cited by applicant]
US 5846261A · Kotula et al. · 1998 [cited by applicant]
US 5910144A · Hayashi · 1999 [cited by applicant]
US 5916193A · Stevens et al. · 1999 [cited by applicant]
US 5941850A · Shah et al. · 1999 [cited by applicant]
US 5951583A · Jensen et al. · 1999 [cited by applicant]
US 5957949A · Leonhardt et al. · 1999 [cited by applicant]
US 5990379A · Gregory · 1999 [cited by applicant]
US 6007544A · Kim · 1999 [cited by applicant]
US 6027518A · Gaber · 2000 [cited by applicant]
US 6039755A · Edwin et al. · 2000 [cited by applicant]
US 6039759A · Carpentier et al. · 2000 [cited by applicant]
US 6059810A · Brown et al. · 2000 [cited by applicant]
US 6086610A · Duerig et al. · 2000 [cited by applicant]
US 6111520A · Allen et al. · 2000 [cited by applicant]
US 6117159A · Huebsch et al. · 2000 [cited by applicant]
US 6120534A · Ruiz · 2000 [cited by applicant]
US 6124523A · Banas et al. · 2000 [cited by applicant]
US 6126686A · Badylak et al. · 2000 [cited by applicant]
US 6165188A · Saadat et al. · 2000 [cited by applicant]
US 6210318B1 · Lederman · 2001 [cited by applicant]
US 6214029B1 · Thill et al. · 2001 [cited by applicant]
US 6214039B1 · Banas et al. · 2001 [cited by applicant]
US 6217541B1 · Yu · 2001 [cited by applicant]
US 6221096B1 · Aiba et al. · 2001 [cited by applicant]
US 6231587B1 · Makower · 2001 [cited by applicant]
US 6242762B1 · Brown et al. · 2001 [cited by applicant]
US 6245099B1 · Edwin et al. · 2001 [cited by applicant]
US 6254564B1 · Wilk et al. · 2001 [cited by applicant]
US 6260552B1 · Mortier et al. · 2001 [cited by applicant]
US 6264684B1 · Banas et al. · 2001 [cited by applicant]
US 6270515B1 · Linden et al. · 2001 [cited by applicant]
US 6270526B1 · Cox · 2001 [cited by applicant]
US 6277078B1 · Porat et al. · 2001 [cited by applicant]
US 6278379B1 · Allen et al. · 2001 [cited by applicant]
US 6290728B1 · Phelps et al. · 2001 [cited by applicant]
US 6302892B1 · Wilk · 2001 [cited by applicant]
US 6306141B1 · Jervis · 2001 [cited by applicant]
US 6328699B1 · Eigler et al. · 2001 [cited by applicant]
US 6344022B1 · Jarvik · 2002 [cited by applicant]
US 6358277B1 · Duran · 2002 [cited by applicant]
US 6391036B1 · Berg et al. · 2002 [cited by applicant]
US 6398803B1 · Layne et al. · 2002 [cited by applicant]
US 6406422B1 · Landesberg · 2002 [cited by applicant]
US 6447539B1 · Nelson et al. · 2002 [cited by applicant]
US 6451051B2 · Drasler et al. · 2002 [cited by applicant]
US 6458153B1 · Bailey et al. · 2002 [cited by applicant]
US 6468303B1 · Amplatz et al. · 2002 [cited by applicant]
US 6475136B1 · Forsell · 2002 [cited by applicant]
US 6478776B1 · Rosenman et al. · 2002 [cited by applicant]
US 6485507B1 · Walak et al. · 2002 [cited by applicant]
US 6488702B1 · Besselink · 2002 [cited by applicant]
US 6491705B2 · Gifford, III et al. · 2002 [cited by applicant]
US 6527698B1 · Kung et al. · 2003 [cited by applicant]
US 6544208B2 · Ethier et al. · 2003 [cited by applicant]
US 6547814B2 · Edwin et al. · 2003 [cited by applicant]
US 6562066B1 · Martin · 2003 [cited by applicant]
US 6572652B2 · Shaknovich · 2003 [cited by applicant]
US 6579314B1 · Lombardi et al. · 2003 [cited by applicant]
US 6589198B1 · Soltanpour et al. · 2003 [cited by applicant]
US 6616675B1 · Evard et al. · 2003 [cited by applicant]
US 6632169B2 · Korakianitis et al. · 2003 [cited by applicant]
US 6638303B1 · Campbell · 2003 [cited by applicant]
US 6641610B2 · Wolf et al. · 2003 [cited by applicant]
US 6645220B1 · Huter et al. · 2003 [cited by applicant]
US 6652578B2 · Bailey et al. · 2003 [cited by applicant]
US 6685664B2 · Levin et al. · 2004 [cited by applicant]
US 6712836B1 · Berg et al. · 2004 [cited by applicant]
US 6740115B2 · Lombardi et al. · 2004 [cited by applicant]
US 6758858B2 · McCrea et al. · 2004 [cited by applicant]
US 6764507B2 · Shanley et al. · 2004 [cited by applicant]
US 6770087B2 · Layne et al. · 2004 [cited by applicant]
US 6797217B2 · McCrea et al. · 2004 [cited by applicant]
US 6890350B1 · Walak · 2005 [cited by applicant]
US 6923829B2 · Boyle et al. · 2005 [cited by applicant]
US 6970742B2 · Mann et al. · 2005 [cited by applicant]
US 7001409B2 · Amplatz · 2006 [cited by applicant]
US 7004966B2 · Edwin et al. · 2006 [cited by applicant]
US 7025777B2 · Moore · 2006 [cited by applicant]
US 7060150B2 · Banas et al. · 2006 [cited by applicant]
US 7083640B2 · Lombardi et al. · 2006 [cited by applicant]
US 7115095B2 · Eigler et al. · 2006 [cited by applicant]
US 7118600B2 · Dua et al. · 2006 [cited by applicant]
US 7137953B2 · Eigler et al. · 2006 [cited by applicant]
US 7147604B1 · Allen et al. · 2006 [cited by applicant]
US 7149587B2 · Wardle et al. · 2006 [cited by applicant]
US 7169160B1 · Middleman et al. · 2007 [cited by applicant]
US 7169172B2 · Levine et al. · 2007 [cited by applicant]
US 7195594B2 · Eigler et al. · 2007 [cited by applicant]
US 7208010B2 · Shanley et al. · 2007 [cited by applicant]
US 7226558B2 · Nieman et al. · 2007 [cited by applicant]
US 7245117B1 · Joy et al. · 2007 [cited by applicant]
US 7294115B1 · Wilk · 2007 [cited by applicant]
US 7306756B2 · Edwin et al. · 2007 [cited by applicant]
US 7402899B1 · Whiting et al. · 2008 [cited by applicant]
US 7439723B2 · Allen et al. · 2008 [cited by applicant]
US 7468071B2 · Edwin et al. · 2008 [cited by applicant]
US 7483743B2 · Mann et al. · 2009 [cited by applicant]
US 7498799B2 · Allen et al. · 2009 [cited by applicant]
US 7509169B2 · Eigler et al. · 2009 [cited by applicant]
US 7550978B2 · Joy et al. · 2009 [cited by applicant]
US 7578899B2 · Edwin et al. · 2009 [cited by applicant]
US 7590449B2 · Mann et al. · 2009 [cited by applicant]
US 7615010B1 · Najafi et al. · 2009 [cited by applicant]
US 7621879B2 · Eigler et al. · 2009 [cited by applicant]
US 7679355B2 · Allen et al. · 2010 [cited by applicant]
US 7717854B2 · Mann et al. · 2010 [cited by applicant]
US 7794473B2 · Tessmer et al. · 2010 [cited by applicant]
US 7839153B2 · Joy et al. · 2010 [cited by applicant]
US 7842083B2 · Shanley et al. · 2010 [cited by applicant]
US 7854172B2 · O'Brien et al. · 2010 [cited by applicant]
US 7862513B2 · Eigler et al. · 2011 [cited by applicant]
US 7914639B2 · Layne et al. · 2011 [cited by applicant]
US 7939000B2 · Edwin et al. · 2011 [cited by applicant]
US 7988724B2 · Salahieh et al. · 2011 [cited by applicant]
US 7993383B2 · Hartley et al. · 2011 [cited by applicant]
US 8012194B2 · Edwin et al. · 2011 [cited by applicant]
US 8016877B2 · Seguin et al. · 2011 [cited by applicant]
US 8021420B2 · Dolan · 2011 [cited by applicant]
US 8025625B2 · Allen · 2011 [cited by applicant]
US 8025668B2 · McCartney · 2011 [cited by applicant]
US 8043360B2 · McNamara et al. · 2011 [cited by applicant]
US 8070708B2 · Rottenberg et al. · 2011 [cited by applicant]
US 8091556B2 · Keren et al. · 2012 [cited by applicant]
US 8096959B2 · Stewart et al. · 2012 [cited by applicant]
US 8137605B2 · McCrea et al. · 2012 [cited by applicant]
US 8142363B1 · Eigler et al. · 2012 [cited by applicant]
US 8147545B2 · Avior · 2012 [cited by applicant]
US 8157852B2 · Bloom et al. · 2012 [cited by applicant]
US 8157860B2 · McNamara et al. · 2012 [cited by applicant]
US 8157940B2 · Edwin et al. · 2012 [cited by applicant]
US 8158041B2 · Colone · 2012 [cited by applicant]
US 8187321B2 · Shanley et al. · 2012 [cited by applicant]
US 8202313B2 · Shanley et al. · 2012 [cited by applicant]
US 8206435B2 · Shanley et al. · 2012 [cited by applicant]
US 8216398B2 · Bledsoe et al. · 2012 [cited by applicant]
US 8235916B2 · Whiting et al. · 2012 [cited by applicant]
US 8235933B2 · Keren et al. · 2012 [cited by applicant]
US 8246677B2 · Ryan · 2012 [cited by applicant]
US 8287589B2 · Otto et al. · 2012 [cited by applicant]
US 8298150B2 · Mann et al. · 2012 [cited by applicant]
US 8298244B2 · Garcia et al. · 2012 [cited by applicant]
US 8303511B2 · Eigler et al. · 2012 [cited by applicant]
US 8313524B2 · Edwin et al. · 2012 [cited by applicant]
US 8328751B2 · Keren et al. · 2012 [cited by applicant]
US 8337650B2 · Edwin et al. · 2012 [cited by applicant]
US 8348996B2 · Tuval et al. · 2013 [cited by applicant]
US 8357193B2 · Phan et al. · 2013 [cited by applicant]
US 8398708B2 · Meiri et al. · 2013 [cited by applicant]
US 8460366B2 · Rowe · 2013 [cited by applicant]
US 8468667B2 · Straubinger et al. · 2013 [cited by applicant]
US 8480594B2 · Eigler et al. · 2013 [cited by applicant]
US 8579966B2 · Seguin et al. · 2013 [cited by applicant]
US 8597225B2 · Kapadia · 2013 [cited by applicant]
US 8617337B2 · Layne et al. · 2013 [cited by applicant]
US 8617441B2 · Edwin et al. · 2013 [cited by applicant]
US 8652284B2 · Bogert et al. · 2014 [cited by applicant]
US 8660667B1 · Kusumoto · 2014 [cited by applicant]
US 8665086B2 · Miller et al. · 2014 [cited by applicant]
US 8696611B2 · Nitzan et al. · 2014 [cited by applicant]
US 8790241B2 · Edwin et al. · 2014 [cited by applicant]
US 8882697B2 · Celermajer et al. · 2014 [cited by applicant]
US 8882798B2 · Schwab et al. · 2014 [cited by applicant]
US 8911489B2 · Ben-Muvhar · 2014 [cited by applicant]
US 9005155B2 · Sugimoto · 2015 [cited by applicant]
US 9034034B2 · Nitzan et al. · 2015 [cited by applicant]
US 9055917B2 · Mann et al. · 2015 [cited by applicant]
US 9060696B2 · Eigler et al. · 2015 [cited by applicant]
US 9067050B2 · Gallagher et al. · 2015 [cited by applicant]
US 9205236B2 · McNamara et al. · 2015 [cited by applicant]
US 9220429B2 · Nabutovsky et al. · 2015 [cited by applicant]
US 9232997B2 · Sugimoto et al. · 2016 [cited by applicant]
US 9358371B2 · McNamara et al. · 2016 [cited by applicant]
US 9393115B2 · Tabor et al. · 2016 [cited by applicant]
US 9456812B2 · Finch et al. · 2016 [cited by applicant]
US 9622895B2 · Cohen et al. · 2017 [cited by applicant]
US 9629715B2 · Nitzan et al. · 2017 [cited by applicant]
US 9681948B2 · Levi et al. · 2017 [cited by applicant]
US 9707382B2 · Nitzan et al. · 2017 [cited by applicant]
US 9713696B2 · Yacoby et al. · 2017 [cited by applicant]
US 9724499B2 · Rottenberg et al. · 2017 [cited by applicant]
US 9757107B2 · McNamara et al. · 2017 [cited by applicant]
US 9789294B2 · Taft et al. · 2017 [cited by applicant]
US 9918677B2 · Eigler et al. · 2018 [cited by applicant]
US 9943670B2 · Keren et al. · 2018 [cited by applicant]
US 9980815B2 · Nitzan et al. · 2018 [cited by applicant]
US 10045766B2 · McNamara et al. · 2018 [cited by applicant]
US 10047421B2 · Khan et al. · 2018 [cited by applicant]
US 10076403B1 · Eigler et al. · 2018 [cited by applicant]
US 10105103B2 · Goldshtein et al. · 2018 [cited by applicant]
US 10111741B2 · Michalak · 2018 [cited by applicant]
US 10207087B2 · Keren et al. · 2019 [cited by applicant]
US 10207807B2 · Moran et al. · 2019 [cited by applicant]
US 10251740B2 · Eigler et al. · 2019 [cited by applicant]
US 10251750B2 · Alexander et al. · 2019 [cited by applicant]
US 10265169B2 · Desrosiers et al. · 2019 [cited by applicant]
US 10299687B2 · Nabutovsky et al. · 2019 [cited by applicant]
US 10357320B2 · Beira · 2019 [cited by applicant]
US 10357357B2 · Levi et al. · 2019 [cited by applicant]
US 10368981B2 · Nitzan et al. · 2019 [cited by applicant]
US 10463490B2 · Rottenberg et al. · 2019 [cited by applicant]
US 10478594B2 · Yacoby et al. · 2019 [cited by applicant]
US 10542994B2 · Ben-Muvhar et al. · 2020 [cited by applicant]
US 10548725B2 · Alkhatib et al. · 2020 [cited by applicant]
US 10561423B2 · Sharma · 2020 [cited by applicant]
US 10583002B2 · Lane et al. · 2020 [cited by applicant]
US 10639459B2 · Nitzan et al. · 2020 [cited by applicant]
US 10828151B2 · Nitzan et al. · 2020 [cited by applicant]
US 10835394B2 · Nae et al. · 2020 [cited by applicant]
US 10898698B1 · Eigler et al. · 2021 [cited by applicant]
US 10912645B2 · Rottenberg et al. · 2021 [cited by applicant]
US 10925706B2 · Eigler et al. · 2021 [cited by applicant]
US 10940296B2 · Keren · 2021 [cited by applicant]
US 11109988B2 · Rosen et al. · 2021 [cited by applicant]
US 11135054B2 · Nitzan et al. · 2021 [cited by applicant]
US 11234702B1 · Eigler et al. · 2022 [cited by applicant]
US 11253353B2 · Levi et al. · 2022 [cited by applicant]
US 11255379B2 · Baskin et al. · 2022 [cited by applicant]
US 11291807B2 · Eigler et al. · 2022 [cited by applicant]
US 11304831B2 · Nae et al. · 2022 [cited by applicant]
US 11382747B2 · Rottenberg et al. · 2022 [cited by applicant]
US 11458287B2 · Eigler et al. · 2022 [cited by applicant]
US 11497631B2 · Rosen et al. · 2022 [cited by applicant]
US 11607327B2 · Nae et al. · 2023 [cited by applicant]
US 11612385B2 · Nae et al. · 2023 [cited by applicant]
US 11690976B2 · Yacoby et al. · 2023 [cited by applicant]
US 11813386B2 · Nae et al. · 2023 [cited by applicant]
US 11850138B2 · Eigler et al. · 2023 [cited by applicant]
US 11865282B2 · Nae et al. · 2024 [cited by applicant]
US 12115328B2 · Nae et al. · 2024 [cited by applicant]
US 12186176B2 · Eigler et al. · 2025 [cited by applicant]
US 12186510B2 · Keren · 2025 [cited by applicant]
US 20010007956A1 · Letac et al. · 2001 [cited by applicant]
US 20010020154A1 · Bigus et al. · 2001 [cited by applicant]
US 20010021872A1 · Bailey et al. · 2001 [cited by applicant]
US 20020042565A1 · Cooper et al. · 2002 [cited by applicant]
US 20020051730A1 · Bodnar et al. · 2002 [cited by applicant]
US 20020099431A1 · Armstrong et al. · 2002 [cited by applicant]
US 20020120277A1 · Hauschild et al. · 2002 [cited by applicant]
US 20020165479A1 · Wilk · 2002 [cited by applicant]
US 20020165606A1 · Wolf et al. · 2002 [cited by applicant]
US 20020169371A1 · Gilderdale · 2002 [cited by applicant]
US 20020169377A1 · Khairkhahan et al. · 2002 [cited by applicant]
US 20020173742A1 · Keren et al. · 2002 [cited by applicant]
US 20020183628A1 · Reich et al. · 2002 [cited by applicant]
US 20030028213A1 · Thill et al. · 2003 [cited by applicant]
US 20030045902A1 · Weadock · 2003 [cited by applicant]
US 20030097172A1 · Shalev et al. · 2003 [cited by applicant]
US 20030100920A1 · Akin et al. · 2003 [cited by applicant]
US 20030125798A1 · Martin · 2003 [cited by applicant]
US 20030136417A1 · Fonseca et al. · 2003 [cited by applicant]
US 20030139819A1 · Beer et al. · 2003 [cited by applicant]
US 20030176914A1 · Rabkin et al. · 2003 [cited by applicant]
US 20030209835A1 · Chun et al. · 2003 [cited by applicant]
US 20030216679A1 · Wolf et al. · 2003 [cited by applicant]
US 20030216803A1 · Ledergerber · 2003 [cited by applicant]
US 20040010219A1 · McCusker et al. · 2004 [cited by applicant]
US 20040016514A1 · Nien · 2004 [cited by applicant]
US 20040073242A1 · Chanduszko · 2004 [cited by applicant]
US 20040077988A1 · Tweden et al. · 2004 [cited by applicant]
US 20040087984A1 · Kupiecki et al. · 2004 [cited by applicant]
US 20040088045A1 · Cox · 2004 [cited by applicant]
US 20040093075A1 · Kuehne · 2004 [cited by applicant]
US 20040102797A1 · Golden et al. · 2004 [cited by applicant]
US 20040116999A1 · Ledergerber · 2004 [cited by applicant]
US 20040138743A1 · Myers et al. · 2004 [cited by applicant]
US 20040147869A1 · Wolf et al. · 2004 [cited by applicant]
US 20040147871A1 · Burnett · 2004 [cited by applicant]
US 20040147886A1 · Bonni · 2004 [cited by applicant]
US 20040147969A1 · Mann et al. · 2004 [cited by applicant]
US 20040162514A1 · Alferness et al. · 2004 [cited by applicant]
US 20040193261A1 · Berreklouw · 2004 [cited by applicant]
US 20040210190A1 · Kohler et al. · 2004 [cited by applicant]
US 20040210307A1 · Khairkhahan · 2004 [cited by applicant]
US 20040225352A1 · Osborne et al. · 2004 [cited by applicant]
US 20050003327A1 · Elian et al. · 2005 [cited by applicant]
US 20050033327A1 · Gainor et al. · 2005 [cited by applicant]
US 20050033351A1 · Newton · 2005 [cited by applicant]
US 20050065589A1 · Schneider et al. · 2005 [cited by applicant]
US 20050125032A1 · Whisenant et al. · 2005 [cited by applicant]
US 20050137682A1 · Justino · 2005 [cited by applicant]
US 20050148925A1 · Rottenberg et al. · 2005 [cited by applicant]
US 20050149166A1 · Schaeffer et al. · 2005 [cited by applicant]
US 20050165344A1 · Dobak · 2005 [cited by applicant]
US 20050182486A1 · Gabbay · 2005 [cited by applicant]
US 20050228480A1 · Douglas et al. · 2005 [cited by applicant]
US 20050267524A1 · Chanduszko · 2005 [cited by applicant]
US 20050283231A1 · Haug et al. · 2005 [cited by applicant]
US 20050288596A1 · Eigler et al. · 2005 [cited by applicant]
US 20050288706A1 · Widomski et al. · 2005 [cited by applicant]
US 20050288786A1 · Chanduszko · 2005 [cited by applicant]
US 20060009800A1 · Christianson et al. · 2006 [cited by applicant]
US 20060025857A1 · Bergheim et al. · 2006 [cited by applicant]
US 20060052821A1 · Abbott et al. · 2006 [cited by applicant]
US 20060106449A1 · Ben Muvhar · 2006 [cited by applicant]
US 20060111660A1 · Wolf et al. · 2006 [cited by applicant]
US 20060111704A1 · Brenneman et al. · 2006 [cited by applicant]
US 20060116710A1 · Corcoran et al. · 2006 [cited by applicant]
US 20060122522A1 · Chavan et al. · 2006 [cited by applicant]
US 20060122647A1 · Callaghan et al. · 2006 [cited by applicant]
US 20060167541A1 · Lattouf · 2006 [cited by applicant]
US 20060184231A1 · Rucker · 2006 [cited by applicant]
US 20060212110A1 · Osborne et al. · 2006 [cited by applicant]
US 20060241745A1 · Solem · 2006 [cited by applicant]
US 20060256611A1 · Bednorz et al. · 2006 [cited by applicant]
US 20060282157A1 · Hill et al. · 2006 [cited by applicant]
US 20070010852A1 · Blaeser et al. · 2007 [cited by applicant]
US 20070021739A1 · Weber · 2007 [cited by applicant]
US 20070043435A1 · Seguin et al. · 2007 [cited by applicant]
US 20070073337A1 · Abbott et al. · 2007 [cited by applicant]
US 20070129756A1 · Abbott et al. · 2007 [cited by applicant]
US 20070191863A1 · De Juan, Jr. et al. · 2007 [cited by applicant]
US 20070213813A1 · Von Segesser et al. · 2007 [cited by applicant]
US 20070249985A1 · Brenneman et al. · 2007 [cited by applicant]
US 20070276413A1 · Nobles · 2007 [cited by applicant]
US 20070276414A1 · Nobles · 2007 [cited by applicant]
US 20070282157A1 · Rottenberg et al. · 2007 [cited by applicant]
US 20070299384A1 · Faul et al. · 2007 [cited by applicant]
US 20080034836A1 · Eigler et al. · 2008 [cited by applicant]
US 20080086205A1 · Gordy et al. · 2008 [cited by applicant]
US 20080125861A1 · Webler et al. · 2008 [cited by applicant]
US 20080171944A1 · Brenneman et al. · 2008 [cited by applicant]
US 20080177300A1 · Mas et al. · 2008 [cited by applicant]
US 20080221609A1 · McGuckin et al. · 2008 [cited by applicant]
US 20080243081A1 · Nance et al. · 2008 [cited by applicant]
US 20080262602A1 · Wilk et al. · 2008 [cited by applicant]
US 20080264102A1 · Berra · 2008 [cited by applicant]
US 20080319525A1 · Tieu et al. · 2008 [cited by applicant]
US 20090030499A1 · Bebb et al. · 2009 [cited by applicant]
US 20090054976A1 · Tuval et al. · 2009 [cited by applicant]
US 20090125104A1 · Hoffman · 2009 [cited by applicant]
US 20090149947A1 · Frohwitter · 2009 [cited by applicant]
US 20090198315A1 · Boudjemline · 2009 [cited by applicant]
US 20090248133A1 · Bloom · 2009 [cited by examiner]
US 20090276040A1 · Rowe et al. · 2009 [cited by applicant]
US 20090319037A1 · Rowe et al. · 2009 [cited by applicant]
US 20100004740A1 · Seguin et al. · 2010 [cited by applicant]
US 20100022940A1 · Thompson · 2010 [cited by applicant]
US 20100023046A1 · Heidner et al. · 2010 [cited by applicant]
US 20100057192A1 · Celermajer · 2010 [cited by applicant]
US 20100069836A1 · Satake · 2010 [cited by applicant]
US 20100070022A1 · Kuehling · 2010 [cited by applicant]
US 20100081867A1 · Fishler et al. · 2010 [cited by applicant]
US 20100100167A1 · Bortlein et al. · 2010 [cited by applicant]
US 20100121434A1 · Paul et al. · 2010 [cited by applicant]
US 20100125288A1 · Gelfand et al. · 2010 [cited by applicant]
US 20100179590A1 · Fortson et al. · 2010 [cited by applicant]
US 20100191326A1 · Alkhatib · 2010 [cited by applicant]
US 20100249491A1 · Farnan et al. · 2010 [cited by applicant]
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