Patent Application
Utility
App. No. 18/968,749
· Confirmation No. 4907
MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT
Inventors:
Shigeo MATSUDA, Mark K. SCHLEGEL, Maja JANAS, Vasant R. JADHAV, Martin MAIER, Klaus CHARISSE, Muthiah MANOHARAN, Kallathottathil G. RAJEEV, Jayaprakash K. NAIR
Applicant:
Alnylam Pharmaceuticals, Inc.
Docketed New Case - Ready for Examination
View Publication ↗
|
⬇ PDF
|
Code | Description | Pages | ||
|---|---|---|---|---|---|
| 2025-06-26 | NTC.PUB |
Notice of Publication | 1 | View | |
| 2025-03-18 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2025-03-18 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-03-14 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | — | View | |
| 2025-03-14 | PEFRSEQ |
Response to Pre-Exam Sequence Notice | 2 | View | |
| 2025-03-14 | N417 |
Electronic Filing System Acknowledgment Receipt | 3 | View | |
| 2025-03-14 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2025-03-14 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-03-14 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2025-03-14 | REM |
Applicant Arguments/Remarks Made in an Amendment | 322 | View | |
| 2025-03-14 | SPEC |
Specification | 317 | View | |
| 2025-03-14 | CLM |
Claims | 4 | View | |
| 2025-03-14 | ABST |
Abstract | 1 | View | |
| 2025-03-14 | SEQ.XML |
Sequence Listing (XML File) | 1 | View | |
| 2025-03-14 | CRFE |
Sequence Listing in Computer Readable Format, No errors found | 17 | View | |
| 2025-02-11 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 5 | View | |
| 2025-02-11 | N417 |
Electronic Filing System Acknowledgment Receipt | 2 | View | |
| 2025-02-11 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2025-01-15 | APP.FILE.REC |
Filing Receipt | 4 | View | |
| 2025-01-15 | WFEE |
Fee Worksheet (SB06) | 1 | View | |
| 2025-01-15 | SEQ.REQ.DISC |
Requirements for Sequence Disclosure Notice | 4 | View | |
| 2025-01-15 | WELCOME.LET |
Welcome Letter from USPTO Director and Deputy Director | 1 | View | |
| 2025-01-13 | CRFD |
Sequence Listing in Computer Readable Format is Defective | — | View | |
| 2025-01-13 | CRFD |
Sequence Listing in Computer Readable Format is Defective | 29 | View | |
| 2024-12-04 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2024-12-04 | SPEC |
Specification | — | View | |
| 2024-12-04 | IDS |
Information Disclosure Statement (IDS) Form (SB08) | 7 | View | |
| 2024-12-04 | DRW.NONBW |
Drawings-other than black and white line drawings | 47 | View | |
| 2024-12-04 | CRFS |
CRF Statement that Sequence Listing text file (CRF) and paper/pdf Sequence Listing are the same | 1 | View | |
| 2024-12-04 | N417 |
Electronic Filing System Acknowledgment Receipt | 4 | View | |
| 2024-12-04 | PA.. |
Power of Attorney | 1 | View | |
| 2024-12-04 | TRAN.LET |
Transmittal Letter | 1 | View | |
| 2024-12-04 | SPEC |
Specification | 317 | View | |
| 2024-12-04 | CLM |
Claims | 4 | View | |
| 2024-12-04 | ABST |
Abstract | 1 | View | |
| 2024-12-04 | ADS |
Application Data Sheet | 12 | View | |
| 2024-12-04 | OATH |
Oath or Declaration filed | 9 | View | |
| 2024-12-04 | TRNA |
Transmittal of New Application | 2 | View | |
| 2024-12-04 | N417.PYMT |
Electronic Fee Payment | 2 | View | |
| 2024-12-04 | DRW.SUPP |
Drawings-black and white line and/or other drawings | — | View | |
| 2024-12-04 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2024-12-04 | SCORE |
Placeholder sheet indicating presence of supplemental content in Supplemental Complex Repository for Examiners(SCORE) | 1 | View | |
| 2024-12-04 | SEQ.TXT |
Sequence Listing (Text File) | 1 | View |
Inventors
Shigeo MATSUDA
Cambridge, MA
Mark K. SCHLEGEL
Cambridge, MA
Maja JANAS
Cambridge, MA
Vasant R. JADHAV
Cambridge, MA
Martin MAIER
Cambridge, MA
Klaus CHARISSE
Cambridge, MA
Muthiah MANOHARAN
Cambridge, MA
Kallathottathil G. RAJEEV
Cambridge, MA
Jayaprakash K. NAIR
Cambridge, MA
Attorneys & Agents of Record
Classification
USPC
536/24.5
C12N15/113
C12N2310/14
C12N2310/318
C12N2310/323
C12N2310/33
C12N2310/344
C12N2310/53
C12N15/111
C12N2320/53
Prosecution
- Examiner
- CENTRAL, DOCKET
- Art Unit
- OPAP
- Customer No.
- 90162
- Docket No.
- 051058-092330USC2
- Confirmation No.
- 4907
Publication
- Pub. No.
- US20250207131A1
- Pub. Date
- 2025-06-26
Parent
is a Continuation of
→
App. 17/055,710
· US 12,247,203
Filed 2020-11-16
· Patented Case
Parent
PCT
is a National Stage Entry of
→
PCT/US2019/032633
Filed 2019-05-16
· Docketed New Case - Ready for Examination
Parent
Claims priority from a provisional application
→
App. 62/672,405
Filed 2018-05-16
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 62/719,291
Filed 2018-08-17
· Provisional Application Expired
Parent
is a Continuation of
→
App. 17/743,663
· US 12,275,938
Filed 2022-05-13
· Patented Case
Parent
is a Continuation of
→
App. 17/055,710
· US 12,247,203
Filed 2020-11-16
· Patented Case
Parent
PCT
is a National Stage Entry of
→
PCT/US2019/032633
Filed 2019-05-16
· Docketed New Case - Ready for Examination
Parent
Claims priority from a provisional application
→
App. 62/672,405
Filed 2018-05-16
· Provisional Application Expired
Parent
Claims priority from a provisional application
→
App. 62/719,291
Filed 2018-08-17
· Provisional Application Expired
SECURITY INTEREST
Recorded 2025-10-01
from
CHARISSE, KLAUS,
MAIER, MARTIN,
MANOHARAN, MUTHIAH,
RAJEEV, KALLANTHOTTATHIL G.,
SCHLEGEL, MARK K.,
NAIR, JAYAPRAKASH K.,
JADHAV, VASANT R.,
JANAS, MAJA,
MATSUDA, SHIGEO
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded 2025-04-29
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this application's details
Quick Facts
- App. No.
- 18/968,749
- Filed
- 2024-12-04
- Pub. No.
- US20250207131A1
- Examiner
- CENTRAL, DOCKET
- Art Unit
- OPAP
External Links