IP Library › Patent Application 18988066
Patent Application
App. No. 18/988,066

PEPTIDE PHARMACEUTICALS FOR INSULIN RESISTANCE

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Quick Facts
Patent No.
US None
App. No.
18/988,066
Abstract

Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.

Claims (16)

1 - 79 . (canceled)

80 . A peptide comprising structure:

(SEQ. ID. NO. 774)

His 1 -aa 2 -Gln 3 -Gly 4 -Thr 5 -Phe 6 -Thr 7 -Ser 8 -Asp 9 -Tyr 10 -

Ser 11 -Lys 12 -Tyr 13 -Leu 14 -Asp 15 -aa 16 -aa 17 -Ala 18 -

Ala 19 -aa 20 -Glu 21 -Phe 22 -aa 23 -aa 24 -Trp 25 -Leu 26 -aa 27 -

aa 28 -Thr 29 -NH 2 ,

wherein:

aa 2 is Aib;

aa 16 is Glu;

aa 17 is Lys;

aa 20 is Lys;

aa 23 is Ile;

aa 24 is Gln;

aa 27 is Leu; and

aa 28 is Gln.

Assignments (4)
SECURITY INTEREST Recorded May 14, 2025
From: ALTIMMUNE, INC.; SPITFIRE PHARMA, LLC
To: HERCULES CAPITAL, INC., AS AGENT
Reel/Frame 071108/0692 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 19, 2025
From: N, JOHN J.
To: SPITFIRE PHARMA, INC.
Reel/Frame 070262/0605 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 19, 2025
From: SPIRFIRE PHARMA, INC.
To: MEDERIS DIABETES LLC
Reel/Frame 070262/0648 →
AFFIDAVIT OF ADDRESS CHANGE Recorded Feb 19, 2025
From: MEDERIS DIABETES, LLC
To: MEDERIS DIABETES LLC
Reel/Frame 070266/0875 →