FLUORESCENCE DETECTION DEVICE
A fluorescence detection device that has higher detection sensitivity for fluorescence is provided. The fluorescence detection device includes: a light source configured to irradiate a sample with excitation light in a circularly polarized state; a cholesteric liquid crystal layer configured to cause fluorescence emitted by the sample due to the excitation light to transmit therethrough and reflect the excitation light; and detection circuitry configured to detect the fluorescence transmitted through the cholesteric liquid crystal layer.
1 . A fluorescence detection device comprising:
a light source configured to irradiate a sample with excitation light in a circularly polarized state;
a cholesteric liquid crystal layer configured to cause fluorescence emitted by the sample due to the excitation light to transmit therethrough and reflect the excitation light; and
detection circuitry configured to detect the fluorescence transmitted through the cholesteric liquid crystal layer.
2 . The fluorescence detection device according to claim 1 , wherein the light source comprises a light emitter, a polarizing plate configured to cause light from the light emitter to be in a linearly polarized state, and a quarter-wave plate configured to convert the light in the linearly polarized state output from the polarizing plate into the excitation light in the circularly polarized state.
3 . The fluorescence detection device according to claim 1 , further comprising a light-transmitting substrate on which the cholesteric liquid crystal layer is formed.
4 . The fluorescence detection device according to claim 1 , wherein the cholesteric liquid crystal layer comprises a first liquid crystal layer having a first pitch of a helix and a second liquid crystal layer having a second pitch of a helix different from the first pitch.
5 . The fluorescence detection device according to claim 1 , further comprising a lens provided between the cholesteric liquid crystal layer and the detection circuitry and configured to condense the fluorescence.