NICOTINE SALT FORMULATIONS FOR AEROSOL DEVICES AND METHODS THEREOF
A nicotine salt liquid formulation for generating an inhalable aerosol in an electronic cigarette comprising nicotine salt that forms about 0.5% to about 20% nicotine is provided.
1 . An electronic cigarette cartridge, wherein the electronic cigarette cartridge comprises a nicotine salt liquid formulation, wherein:
(a) the nicotine salt liquid formulation comprises a salt of nicotine and malic acid in a liquid carrier;
(b) the salt is present in an amount that forms a nicotine concentration of 0.5% (w/w) to 20% (w/w) in the nicotine salt liquid formulation; and
(c) the nicotine salt liquid formulation generates an inhalable aerosol upon heating in the electronic cigarette.
2 . The electronic cigarette cartridge of claim 1 , wherein the liquid carrier comprises glycerol, propylene glycol, trimethylene glycol, water, ethanol or combinations thereof.
3 . The electronic cigarette cartridge of claim 1 , wherein the liquid carrier comprises propylene glycol and glycerol.
4 . The electronic cigarette cartridge of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 20% (w/w) in the nicotine salt liquid formulation.
5 . The electronic cigarette cartridge of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 18% (w/w) in the nicotine salt liquid formulation.
6 . The electronic cigarette cartridge of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 3% (w/w) to 15% (w/w) in the nicotine salt liquid formulation.
7 . The electronic cigarette cartridge of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 4% (w/w) to 12% (w/w) in the nicotine salt liquid formulation.
8 . The electronic cigarette cartridge of claim 1 , wherein the nicotine salt liquid formulation further comprises a flavorant.
9 . The electronic cigarette cartridge of claim 1 , wherein the nicotine salt liquid formulation further comprises one or more additional organic acids.
10 . An electronic cigarette comprising the electronic cigarette cartridge of claim 1 .
11 . The electronic cigarette of claim 10 , wherein the electronic cigarette cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.
12 . A method of providing nicotine to a user, the method comprising:
(a) heating a nicotine salt liquid formulation in an electronic cigarette to produce an inhalable aerosol, and
(b) inhalation of the aerosol by the user;
wherein:
(i) the nicotine salt liquid formulation comprises a salt of nicotine and malic acid in a liquid carrier; and
(ii) the salt is present in an amount that forms a nicotine concentration of 0.5% (w/w) to 20% (w/w) in the nicotine salt liquid formulation.
13 . The method of claim 12 , wherein the liquid carrier comprises glycerol, propylene glycol, trimethylene glycol, water, ethanol or combinations thereof.
14 . The method of claim 12 , wherein the liquid carrier comprises propylene glycol and glycerol.
15 . The method of claim 12 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 18% (w/w) in the nicotine salt liquid formulation.
16 . The method of claim 12 , wherein the salt is present in an amount that forms a nicotine concentration of 3% (w/w) to 15% (w/w) in the nicotine salt liquid formulation.
17 . The method of claim 12 , wherein the salt is present in an amount that forms a nicotine concentration of 4% (w/w) to 12% (w/w) in the nicotine salt liquid formulation.
18 . The method of claim 12 , wherein the nicotine salt liquid formulation further comprises a flavorant.
19 . The method of claim 12 , wherein the nicotine salt liquid formulation further comprises one or more additional organic acids.
20 . The method of claim 12 , wherein the electronic cigarette comprises a cartridge, and the cartridge is configured to serve as a mouthpiece and a reservoir that holds the nicotine salt liquid formulation.