METHOD OF DISC DECOMPRESSION AND DISC SUPPLEMENTATION
A method for damaged viable disc regeneration has the steps of identifying the damaged viable disc and inserting a cannula via Kambin's Triangle to an edge of an outer annulus of the disc; introducing a trocar into the cannula and penetrating the trocar into a central region of nucleus pulposus; removing a tissue biopsy sample from the nucleus pulposus for pathology and removing additional degenerative tissue from the central region to create a void or space; withdrawing the trocar from the cannula and inserting a needle into the cannula to the void or space; and injecting a regenerative disc material through the needle into the void or space to repair the damaged disc.
1 .- 39 . (canceled)
40 . A disc regenerative composition, comprising:
(a) micronized nucleus pulposus; and
(b) allogeneic biological material comprising non-whole cellular components.
41 . The disc regenerative composition of claim 40 , wherein the nucleus pulposus is human-derived and dehydrated.
42 . The disc regenerative composition of claim 40 , wherein the micronized nucleus pulposus has particles sized less than 400 microns.
43 . The disc regenerative composition of claim 42 , wherein the micronized nucleus pulposus has particles sized less than 300 microns.
44 . The disc regenerative composition of claim 40 , wherein the disc regenerative composition is a powder.
45 . The disc regenerative composition of claim 40 , wherein the allogeneic biological material is derived from bone marrow.
46 . A container comprising the disc regenerative composition of claim 40 .
47 . A flowable mixture comprising the disc regenerative composition of claim 40 and a diluent.
48 . The flowable mixture of claim 47 , wherein the mixture has a viscosity that allows flow through a 2-4 mm cannula.
49 . The flowable mixture of claim 47 , wherein the diluent is selected from the group consisting of saline, lactated ringers solution, blood, and platelet rich plasma.
50 . The flowable mixture of claim 47 , further comprising whole cells derived from bone marrow.
51 . The flowable mixture of claim 49 , wherein the whole cells are stem cells.
52 . The flowable mixture of claim 50 , wherein the whole cells are non-expanded whole cells.
53 . The flowable mixture of claim 47 , further comprising one or more growth factors.
54 . An injectable device comprising the flowable mixture of claim 47 .
55 . A method for repairing a damaged disc in a subject, comprising:
injecting the flowable mixture of claim 47 through a cannula into a disc space in the subject to repair the damaged disc.
56 . A method for repairing a damaged disc in a subject, comprising:
(a) rehydrating the composition of claim 40 into a flowable mixture; and
(b) injecting the hydrated composition of step (a) through a cannula into a disc space in the subject to repair the damaged disc.