SYSTEMS, APPARATUSES, AND METHODS FOR FILTERING HIGH VOLTAGE NOISE INDUCED BY PULSED ELECTRIC FIELD ABLATION
Systems, apparatuses, and methods for electroporation ablation therapy are disclosed, with a protection device for protecting electronic circuitry, devices, and/or other components from induced currents and voltages generated during a cardiac ablation procedure. A system can include an ablation device near cardiac tissue of a heart. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the ablation device and configured to repeatedly deliver the pulse waveform to the ablation device in synchrony with a set of cardiac cycles of the heart. The system can further include a protection device configured to suppress induced current and voltage in an electronic device coupled to the protection device.
1 . An apparatus, comprising:
a protection device coupleable between a first electronic device and a second electronic device, the first electronic device disposable near tissue of a subject such that currents can be induced in the first electronic device by voltage pulse waveforms delivered to a set of electrodes near tissue, the protection device including:
a set of balun circuits connected in series and collectively configured to reduce the currents induced in the first electronic device over a set of predetermined frequency ranges.
2 . The apparatus of claim 1 , further comprising: a signal generator configured to generate the voltage pulse waveform, the signal generator coupled to the set of electrodes and configured to deliver the voltage pulse waveform to the set of electrodes.
3 . The apparatus of claim 2 , further comprising: a cardiac stimulator configured to deliver pacing signals to the first electronic device, the cardiac stimulator being the second electronic device.
4 . The apparatus of claim 2 , wherein the first electronic device is a pacing device including a set of leads, and the second electronic device is a cardiac stimulator configured to deliver pacing signals to the pacing device.
5 . The apparatus of claim 2 , wherein each predetermined frequency range of the set of predetermined frequency ranges at least partially overlaps at least one other predetermined frequency range of the set of predetermined frequency ranges.
6 . The apparatus of claim 5 , wherein each predetermined frequency range of the set of predetermined frequency ranges has a resonance peak associated with a balun circuit of the set of balun circuits.
7 . The apparatus of claim 2 , wherein the protection device further includes one or more inductors configured to reduce an alternating current of the currents induced in the first electronic device.
8 . The apparatus of claim 7 , wherein the set of balun circuits are coupled between the one or more inductors and the first electronic device.
9 . The apparatus of claim 7 , wherein the one or more inductors includes first and second sets of inductors, the first set of inductors coupled between the set of balun circuits and the first electronic device, the second set of inductors coupled between the set of balun circuits and the second electronic device.
10 . The system of claim 2 , wherein at least one balun circuit of the set of balun circuits includes an inductor in parallel with a capacitor and a resistor.
11 . The system of claim 2 , wherein at least one balun circuit of the set of balun circuits includes a coaxial cable winding including first and second conductors, the first conductor coupled to a first lead of the first electronic device and the second conductor coupled to a second lead of the first electronic device.
12 . A method, comprising:
delivering, using a pacing device positioned near cardiac tissue of a heart, pacing signals to the heart;
delivering, using a signal generator, voltage pulse waveforms to an ablation device positioned near tissue to ablate the tissue;
inducing, in response to delivering the voltage pulse waveform, currents in a set of first electronic devices positioned near the cardiac tissue, the set of first electronic devices including the pacing device; and
reducing, using a protection device coupled between the set of first electronic devices and a second electronic device, the currents induced in the set of first electronic devices.
13 . The method of claim 12 , wherein the second electronic device is a cardiac stimulator configured to generate the pacing signals.
14 . The method of claim 12 , wherein the second electronic device is an electrocardiogram (ECG) recording system.
15 . The method of claim 12 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes reducing, using one or more transformers or capacitors of the protection device, common mode currents or differential mode currents of the currents induced in the set of first electronic devices.
16 . The method of claim 12 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes shunting, using a set of diodes of the protection device, high voltages away from the second electronic device.
17 . The method of claim 12 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes reducing, using one or more inductors of balun circuits of the protection device, alternating currents having frequencies within a predetermined range of frequencies of the currents induced in the set of first electronic devices.
18 . The method of claim 14 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes reducing, using one or more transformers or capacitors of the protection device, common mode currents or differential mode currents of the currents induced in the set of first electronic devices.
19 . The method of claim 14 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes shunting, using a set of diodes of the protection device, high voltages away from the second electronic device.
20 . The method of claim 14 , wherein reducing, using the protection device, the current induced in the set of first electronic devices includes reducing, using one or more inductors of balun circuits of the protection device, alternating currents having frequencies within a predetermined range of frequencies of the currents induced in the set of first electronic devices.