Centrifuge Accessory for Transdermal Pens
Described herein is a centrifuge accessory for processing a transdermal pen comprising a base having a central axis aligned with a rotor of a centrifuge, a pen support for removably attaching the transdermal pen to the base in a radial configuration, and a rod protruding from base. The rod has a central axis aligned with the transdermal pen when the transdermal pen is attached to the base.
1 . A centrifuge accessory for processing a transdermal pen, the centrifuge accessory comprising:
a base having a central axis aligned with a rotor of a centrifuge;
a pen support for removably attaching the transdermal pen to the base in a radial configuration; and
a rod protruding from base, the rod having a central axis aligned with the transdermal pen when the transdermal pen is attached to the base.
2 . The centrifuge accessory of claim 1 , wherein the base includes planar surface that is normal to a rotation axis of the rotor when the base is operationally attached to the centrifuge.
3 . The centrifuge accessory of claim 1 , wherein the pen support includes a spring clip.
4 . The centrifuge accessory of claim 1 , wherein the pen support includes a pair of spring clips.
5 . The centrifuge accessory of claim 1 , wherein the base is configured to receive up to 14 transdermal pens 1 .
6 . The centrifuge accessory of claim 1 , wherein the rod includes a cylindrical outer surface having a rod diameter that is smaller than a diameter of the transdermal pen at a point where a distal end of the transdermal pen engages the rod during use of the centrifuge.
7 . The centrifuge accessory of claim 1 , wherein the central axis of the rod and a centerline of pen support are aligned with the central axis of the base.
8 . The centrifuge accessory of claim 1 , wherein pen support is configured to orient a longitudinal axis of the transdermal pen normal to a rotational axis of the rotor.
9 . The centrifuge accessory of claim 1 , wherein the rod is positioned at an interior offset from an outer edge of the base and the rod is configured to engage a distal end of the transdermal pen when the transdermal pen is secured to the base.
10 . The centrifuge accessory of claim 1 , wherein the centrifuge accessory is processed in a centrifuge that is substantially closed.
11 . The centrifuge accessory of claim 1 , wherein the centrifuge accessory is processed in a centrifuge that is vented.
12 . A method of removing gaseous phase from a transdermal pen comprising:
securing a base to a centrifuge rotor on a centrifuge in a configuration that causes the base to spin about a central axis when the centrifuge is operated; and
securing the transdermal pen to the base with a pen support coupled to the base in a radial alignment with a rod configured to retain the transdermal pen in a fixed position relation to the base when the centrifuge is operated.
13 . The method of claim 12 further comprising:
operating the centrifuge to induce a gas bubble to migrate to a position such that a longitudinal axis of the transdermal pen transects the gas bubble.
14 . The method of claim 13 further comprising:
priming the transdermal pen to evacuate the gas bubble.
15 . The method of claim 12 , wherein the base includes a planar surface that is normal to a rotation axis of the rotor when the base is operationally attached to the centrifuge rotor.
16 . The method of claim 12 , wherein securing the transdermal pen to the base includes snapping the transdermal pen into a spring clip fixed to the base.
17 . The method of claim 12 , wherein securing the transdermal pen to the base includes securing the transdermal pen into a plurality of spring clips fixed to the base.
18 . The method of claim 12 , wherein up to 14 transdermal pens are processed simultaneously on the base.
19 . The method of claim 12 , wherein the rod includes a cylindrical outer surface having a rod diameter that is smaller than a diameter of the transdermal pen at a point where the transdermal pen engages the rod during use of the centrifuge.
20 . The method of claim 16 , wherein the central axis of the rod and the spring clip are aligned with the central axis of the base.
21 . The method of claim 12 , wherein spring clip is configured to orient a longitudinal axis of the transdermal pen normal to a rotational axis of the rotor.
22 . The method of claim 12 , wherein the rod is positioned at an interior offset from an outer edge of the base.