IP Library › Granted Patent US 12,433,926
Granted Patent B2
US 12,433,926 · App. 19/169,459 · Granted Oct 7, 2025

Burdock seed oil-containing composition and method for producing same

Inventors: Momoko Imai (Osaka, JP); Takashi Shimizu (Osaka, JP)
Assignee: ROHTO PHARMACEUTICAL CO., LTD.
A61K36/28A61K47/14
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Quick Facts
Patent No.
US 12,433,926
App. No.
19/169,459
Granted
Oct 7, 2025
Kind
B2
Abstract

The purpose of the present disclosure is to produce and provide a burdock seed oil-containing composition that is excellent in stability. The present disclosure relates to a composition containing (A) burdock seed oil and (B) triethyl citrate and containing 1 to 7.5 mass % of arctigenin derived from the component (A), and a method for producing the same.

Claims (18)

1. A composition comprising:

(A) burdock seed oil; and

(B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;

wherein arctigenin derived from the component (A) has a content of 1 to 7.5 mass %, and

wherein the component (B) is the triethyl citrate.

2. The composition according to claim 1 , wherein the triethyl citrate has a content of 10 to 90 mass %.

3. A method for producing a composition, comprising blending (A) burdock seed oil and (B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;

wherein the component (A) is blended so that a content of arctigenin derived from the component (A) is from 1 to 7.5 mass %, and

wherein the component (B) is the triethyl citrate.

4. A method for producing a composition, comprising:

blending (A) burdock seed oil and (B) one or more compounds selected from the group consisting of triethyl citrate, diisopropyl adipate, diethyl sebacate, and phenoxyethanol;

wherein arctigenin is included at a content of 2 to 15 mass % into the burdock seed oil.

5. The method for producing a composition according to claim 3 ,

wherein the triethyl citrate has a content of 10 to 90 mass %.

6. The method for producing a composition according to claim 4 ,

wherein the triethyl citrate has a content of 10 to 90 mass %.

7. A method for producing an external preparation or an oral preparation, comprising blending the composition according to claim 1 .

8. A method for producing an external preparation or an oral preparation, comprising blending the composition according to claim 2 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 3, 2025
From: IMAI, MOMOKO; SHIMIZU, TAKASHI
To: ROHTO PHARMACEUTICAL CO., LTD.
Reel/Frame 070728/0199 →
Priority Claims (1)
JP 2022-161418 · Oct 6, 2022 · national
Continuity (2)
Continuation PCTJP2023036324 · Oct 5, 2023
Related Publication 20250228911A1 · Jul 17, 2025
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