IP Library Patent Application 19171168
Patent Application
App. No. 19/171,168

Federated Distributed Computational Graph Platform for Oncological Therapy and Biological Systems Analysis with Neurosymbolic Deep Learning

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Quick Facts
Patent No.
US None
App. No.
19/171,168
Filed
Apr 4, 2025
Art Unit
OPAP
USPC
706/45
Abstract

A federated distributed computational system enables secure biological data analysis and genomic medicine through hybrid simulation capabilities. The system implements a hybrid simulation orchestrator that coordinates classical numerical simulations with machine learning models for biological system analysis, while maintaining secure cross-institutional data exchange. The architecture coordinates multi-scale spatiotemporal synchronization across computational nodes, with each node containing local processing capabilities for biological data analysis and privacy preservation protocols. The system implements cellular machinery assembly analysis, real-time patient data integration, and multi-modal image integration with spatiotemporal health data annotation. Through a distributed graph architecture, the system enables cross-species genetic analysis, environmental response modeling, and multi-scale tensor-based data integration with adaptive dimensionality control. The system implements real-time therapeutic response prediction through multi-modal data analysis, enabling research institutions to collaborate on complex biological analyses while maintaining strict data privacy controls.

Claims (50)

1 . A computer system comprising a hardware memory, wherein the computer system is configured to execute software instructions stored on nontransitory machine-readable storage media that:

establish a network interface configured to interconnect a plurality of computational nodes through a distributed graph architecture, wherein the distributed graph architecture comprises a plurality of secure communication channels between the computational nodes;

allocate computational resources across the distributed graph architecture based on predefined resource optimization parameters;

establish data privacy boundaries between computational nodes by implementing encryption protocols for cross-institutional data exchange;

coordinate distributed computation by transmitting computation instructions to the computational nodes through the secure communication channels;

maintain cross-node knowledge relationships through a knowledge integration framework;

implement multi-scale spatiotemporal synchronization across the computational nodes, wherein each computational node comprises:

a local processing unit configured to execute biological data analysis operations including genetic sequence analysis and gene editing operations;

privacy preservation instructions that implement secure multi-party computation protocols for cross-node collaboration; and

a data storage unit maintaining a hierarchical knowledge graph structure representing multi-domain relationships between biological data elements across spatial and temporal scales;

implement a hybrid simulation orchestrator that coordinates numerical and machine learning models for biological system analysis;

wherein the system implements:

cross-species genetic analysis through phylogenetic integration;

environmental response modeling through spatiotemporal tracking;

multi-scale tensor-based data integration with adaptive dimensionality control; and

real-time therapeutic response prediction through multi-modal data analysis.

2 . The system of claim 1 , wherein the hybrid simulation orchestrator coordinates classical numerical simulations with machine learning models to process fluid-structure interactions and interface modeling problems.

3 . The system of claim 1 , wherein the system implements cellular machinery assembly analysis by simulating protein clustering and complex formation while predicting kinetochore assembly patterns.

4 . The system of claim 1 , wherein the system implements real-time integration of patient monitoring data from wearable devices, medical equipment, and environmental sensors into the multi-scale spatiotemporal synchronization.

5 . The system of claim 1 , wherein the system implements a multi-modal image integration with spatiotemporal health data annotation to generate space-time stabilized patient models.

6 . The system of claim 1 , wherein the system generates dynamic cellular visualizations with interactive therapeutic animations based on patient-specific treatment scenarios.

7 . The system of claim 1 , wherein the system implements obelisk structure analysis by simulating RNA structures and decoding cellular instructions for therapeutic optimization.

8 . The system of claim 1 , wherein the system generates patient-specific immune profiles for immune response prediction and treatment strategy optimization.

9 . The system of claim 1 , wherein the system implements real-time therapeutic response prediction by analyzing multi-modal patient data streams during treatment delivery.

10 . The system of claim 1 , wherein the system implements dynamic interface modeling through adaptive mesh refinement and thermodynamic condition evaluation.

11 . A method performed by a computer system comprising a hardware memory executing software instructions stored on nontransitory machine-readable storage media, the method comprising:

establishing a network interface configured to interconnect a plurality of computational nodes through a distributed graph architecture, wherein the distributed graph architecture comprises a plurality of secure communication channels between the computational nodes;

allocating computational resources across the distributed graph architecture based on predefined resource optimization parameters;

establishing data privacy boundaries between computational nodes by implementing encryption protocols for cross-institutional data exchange;

coordinating distributed computation by transmitting computation instructions to the computational nodes through the secure communication channels;

maintaining cross-node knowledge relationships through a knowledge integration framework;

implementing multi-scale spatiotemporal synchronization across the computational nodes, wherein each computational node comprises:

a local processing unit configured to execute biological data analysis operations including genetic sequence analysis and gene editing operations;

privacy preservation instructions that implement secure multi-party computation protocols for cross-node collaboration; and

a data storage unit maintaining a hierarchical knowledge graph structure representing multi-domain relationships between biological data elements across spatial and temporal scales;

implementing a hybrid simulation orchestrator that coordinates numerical and machine learning models for biological system analysis;

wherein the method implements:

cross-species genetic analysis through phylogenetic integration;

environmental response modeling through spatiotemporal tracking;

multi-scale tensor-based data integration with adaptive dimensionality control; and

real-time therapeutic response prediction through multi-modal data analysis.

12 . The method of claim 11 , wherein the hybrid simulation orchestrator coordinates classical numerical simulations with machine learning models to process fluid-structure interactions and interface modeling problems.

13 . The method of claim 11 , further comprising implementing cellular machinery assembly analysis by simulating protein clustering and complex formation while predicting kinetochore assembly patterns.

14 . The method of claim 11 , further comprising implementing real-time integration of patient monitoring data from wearable devices, medical equipment, and environmental sensors into the multi-scale spatiotemporal synchronization.

15 . The method of claim 11 , further comprising implementing a multi-modal image integration with spatiotemporal health data annotation to generate space-time stabilized patient models.

16 . The method of claim 11 , further comprising generating dynamic cellular visualizations with interactive therapeutic animations based on patient-specific treatment scenarios.

17 . The method of claim 11 , further comprising implementing obelisk structure analysis by simulating RNA structures and decoding cellular instructions for therapeutic optimization.

18 . The method of claim 11 , further comprising generating patient-specific immune profiles for immune response prediction and treatment strategy optimization.

19 . The method of claim 11 , further comprising implementing real-time therapeutic response prediction by analyzing multi-modal patient data streams during treatment delivery.

20 . The method of claim 11 , further comprising implementing dynamic interface modeling through adaptive mesh refinement and thermodynamic condition evaluation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2025
From: CRABTREE, JASON; KELLEY, RICHARD; HOPPER, JASON; PARK, DAVID
To: QOMPLX LLC
Reel/Frame 071702/0317 →