IP Library › Patent Application 19208499
Patent Application
App. No. 19/208,499

MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF

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Quick Facts
Patent No.
US None
App. No.
19/208,499
Abstract

Methods and compositions are provided for extending the half-life of a therapeutic agent A modified therapeutic agent (mTA) comprises a therapeutic agent, a staple, and a half-life extending molecule. The mTAs disclosed herein may be used to treat a disease or a condition in a subject in need thereof.

Claims (17)

1 - 7 . (canceled)

8 . A peptide comprising an amino acid sequence of any one of SEQ ID NO: 30-32, 35-41, or 52-53.

9 . The peptide of claim 8 , comprising the amino acid sequence of any one of SEQ ID NO: 30-32.

10 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 35.

11 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 36.

12 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 37.

13 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 38.

14 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 39.

15 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 40.

16 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 41.

17 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 52.

18 . The peptide of claim 8 , comprising the amino acid sequence of SEQ ID NO: 53.

19 . A peptide comprising an amino acid sequence of any one of SEQ ID NO: 42-51.

20 . The peptide of claim 19 , comprising the amino acid sequence of any one of SEQ ID NO: 42-48.

21 . The peptide of claim 19 , comprising the amino acid sequence of SEQ ID NO: 49.

22 . The peptide of claim 19 , comprising the amino acid sequence of SEQ ID NO: 50.

23 . The peptide of claim 19 , comprising the amino acid sequence of SEQ ID NO: 51.