SYSTEMS AND METHODS FOR RADIALLY COMPRESSIBLE BLOW-FILL-SEAL (BFS) DEVICES
Systems and methods for Blow-Fill-Seal (BFS) vials configured to expel a desired quantity of medicament in response to a designed range of radially inward squeeze-force applications received via a compressible fluid reservoir.
1 . A Blow-Fill-Seal (BFS) vial, comprising:
a fluid seal disposed at a first end of the BFS vial;
at least one external mounting feature formed near the first end of the BFS vial; and
a fluid reservoir disposed between the first end and a second end of the BFS vial, the fluid reservoir being filled with a combination of a gas and a liquid and wherein a liquid to air ratio is greater than one to two (1:2) and the BFS vial comprising a mold separation weld line disposed on a portion of the BFS vial other than the fluid reservoir.
2 . The BFS vial of claim 1 , wherein a wall thickness of the fluid reservoir is between four tenths (0.4-mm) of a millimeter and seven tenths of a millimeter (0.7-mm).
3 . The BFS vial of claim 71 , wherein the wall thickness of the fluid reservoir is fifty-five hundredths of a millimeter (0.55-mm).
4 . The BFS vial of claim 1 , wherein the fluid reservoir comprises a cross-sectional shape defining a low arch having a length to height ratio of approximately twelve to one (12:1).
5 . The BFS vial of claim 1 , wherein the fluid reservoir comprises a length between thirteen millimeters (13.0-mm) and fourteen and one half millimeters (14.5-mm).
6 . The BFS vial of claim 1 , wherein the fluid reservoir comprises a width between eleven and sixth tenths millimeters (11.6-mm) and twelve and twelve and eight tenths millimeters (12.8-mm).
7 . The BFS vial of claim 1 , wherein the BFS vial further comprises:
a cylindrical chamber portion in fluid communication with the fluid reservoir.
8 . The BFS vial of claim 7 , wherein the mold separation weld line is disposed radially across the cylindrical chamber portion.
9 . The BFS vial of claim 1 , wherein the BFS vial further comprises:
a label tab extending axially from the fluid reservoir.
10 . The BFS vial of claim 9 , wherein the label tab comprises an axial detent.
11 . The BFS vial of claim 1 , wherein the liquid to air ratio is one to five (1:5).
12 . The BFS vial of claim 1 , wherein liquid comprises a volume of six tenths of a milliliter (0.6-ml).
13 . The BFS vial of claim 1 , wherein liquid comprises a volume of one and one tenth milliliters (1.1-ml).
14 . The BFS vial of claim 1 , wherein the BFS vial comprises a height of seventy-six millimeters (76-mm).