IP Library › Patent Application 19308717
Patent Application
App. No. 19/308,717

RAS INHIBITORS

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Quick Facts
Patent No.
US None
App. No.
19/308,717
Abstract

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.

Claims (1)

1 . A pharmaceutical composition comprising (i) a means for non-covalently inhibiting a Ras protein in the GTP-bound state (Ras(ON)), and (ii) a pharmaceutically acceptable excipient.

Assignments (2)
SECURITY INTEREST Recorded Jan 12, 2026
From: REVOLUTION MEDICINES, INC.
To: WILMINGTON TRUST, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 073439/0027 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 7, 2026
From: KOLTUN, ELENA S.; CREGG, JAMES; AAY, NAING; BUCKL, ANDREAS; GILL, ADRIAN L.; AGGEN, JAMES; BURNETT, G. LESLIE; PITZEN, JENNIFER; WHALEN, DANIEL M.; KNOX, JOHN E.; LIU, YANG
To: REVOLUTION MEDICINES, INC.
Reel/Frame 073389/0819 →