REAL TIME MANAGEMENT OF DATA RELATING TO PHYSIOLOGICAL CONTROL OF GLUCOSE LEVELS
Integrated glucose monitoring systems, comprising a memory configured to store data relating to at least two glucose measurements of a user, a glucose safe range, and exogenous data. Wherein the at least two glucose measurements of the user are at different time points t 1 and t 2 ; a user interface comprising a display; and a processor comprising computer-executable instructions. Wherein the computer-executable instructions determine a rate of change based on the at least two glucose measurements of the user; determine, based on the at least two glucose measurements of the user and the determined rate of change, a projected glucose level at a future time t 3 ; and provide an alarm at the user interface if, based on at least one point of exogenous data, the projected glucose level at future time t 3 is outside of the glucose safe range.
1 .- 20 . (canceled)
21 . An insulin delivery system, comprising:
a glucose sensor coupled to a transmitter configured to transmit glucose measurement data, wherein a portion of the glucose sensor is configured to be positioned transcutaneously under a skin layer of a user; and
an insulin pump in communication with the transmitter to receive the glucose measurement data, the insulin pump comprising:
a processor; and
a memory storing instructions that, when executed by the processor, cause the processor to:
determine an expected glucose level at a future time point based on a rate of change in the glucose measurement data and exogenous data, wherein the exogenous data comprises one or more of a level of insulin on board, an insulin sensitivity of the user, or a basal rate, and
output an alarm on a graphical user interface of a display when the expected glucose level is above a hyperglycemia alarm threshold or is below a hypoglycemia alarm threshold.
22 . The insulin delivery system of claim 21 , wherein the rate of change is determined based on the glucose measurement data comprising a glucose measurement at a first time and a glucose measurement at a second time after the first time.
23 . The insulin delivery system of claim 22 , wherein the future time point is a predetermined period after the second time.
24 . The insulin delivery system of claim 23 , wherein the predetermined period is 20 minutes.
25 . The insulin delivery system of claim 21 , wherein the processor is further caused to determine if an insulin bolus is administered before the future time point, and wherein an alarm associated with hyperglycemia is not output when an insulin dose is administered.
26 . The insulin delivery system of claim 21 , wherein the processor is further caused to detect if a meal event occurs before the future time point, and wherein an alarm associated with hypoglycemia is not output when the meal event is detected.
27 . The insulin delivery system of claim 21 , wherein the expected glucose level is determined using a model.
28 . The insulin delivery system of claim 21 , wherein the exogenous data comprises each of a level of insulin on board, an insulin sensitivity of the user, and a basal rate.
29 . The insulin delivery system of claim 21 , wherein the processor is further caused to determine a therapy recommendation based on the expected glucose level.
30 . The insulin delivery system of claim 21 , wherein the insulin pump comprises the display.
31 . A method, comprising:
receiving, by a processor of an insulin pump, glucose measurement data from a transmitter coupled to a glucose sensor, wherein the glucose sensor comprises a portion positioned transcutaneously under a skin layer of a user;
determining, by the processor, an expected glucose level at a future time point based on a rate of change in the glucose measurement data and exogenous data, wherein the exogenous data comprises one or more of a level of insulin on board, an insulin sensitivity of the user, or a basal rate; and
outputting an alarm on a graphical user interface of a display when the expected glucose level is above a hyperglycemia alarm threshold or is below a hypoglycemia alarm threshold.
32 . The method of claim 31 , wherein the rate of change is determined based on the glucose measurement data comprising a glucose measurement at a first time and a glucose measurement at a second time after the first time.
33 . The method of claim 32 , wherein the future time point is a predetermined period after the second time.
34 . The method of claim 33 , wherein the predetermined period is 20 minutes.
35 . The method of claim 31 , wherein when the expected glucose level is above the hyperglycemia alarm threshold, the method further comprises:
determining that an insulin bolus is administered; and
cancelling output of the alarm.
36 . The method of claim 31 , wherein when the expected glucose level is below the hypoglycemia alarm threshold, the method further comprises:
determining that a meal event occurred; and
cancelling output of the alarm.
37 . The method of claim 31 , wherein determining the expected glucose level comprises the use of a model.
38 . The method of claim 31 , wherein the exogenous data comprises each of a level of insulin on board, an insulin sensitivity of the user, and a basal rate.
39 . The method of claim 31 , further comprising determining a therapy recommendation based on the expected glucose level.
40 . The method of claim 31 , wherein the insulin pump comprises the display.