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Patent Application Utility PCT National Stage

App. No. 19/483,645 · Confirmation No. 9659

PYRAZOLO[4,3-F]QUINAZOLINE DERIVATIVES AS MODULATORS OF G12D MUTANT KRAS USEFUL FOR THE TREATMENT OF CANCER

Inventors: Inder BHAMRA, Clifford D. JONES, James RYAN, Helen Elizabeth AYLOTT, Daniel J. LENG, Paula JACKSON, Kelvin HO

Applicant: JAZZ PHARMACEUTICALS IRELAND LTD.

Docketed New Case - Ready for Examination

	Code	Description	Pages	PDF
2026-07-07	`M903`	Notice of Designated Office (DO) / Elected Office (EO) Acceptance Mailed	2	View
2026-07-07	`WFEE`	Fee Worksheet (SB06)	1	View
2026-07-07	`APP.FILE.REC`	Filing Receipt	4	View
2026-07-07	`WCLM`	Claims Worksheet (PTO-2022)	1	View
2026-07-07	`WELCOME.LET`	Welcome Letter from USPTO Director and Deputy Director	1	View
2026-02-05	`N417`	Electronic Filing System Acknowledgment Receipt	2	View
2026-02-05	`PA..`	Power of Attorney	1	View
2025-11-12	`ABST`	Abstract	—	View
2025-11-12	`A.PE`	Preliminary Amendment	—	View
2025-11-12	`ADS`	Application Data Sheet	10	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	7	View
2025-11-12	`TRNA`	Transmittal of New Application	4	View
2025-11-12	`ABST`	Abstract	1	View
2025-11-12	`SPEC`	Specification	429	View
2025-11-12	`CLM`	Claims	29	View
2025-11-12	`REF.OTHER`	Other reference-Patent/Application/Search Documents	2	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`REM`	Applicant Arguments/Remarks Made in an Amendment	1	View
2025-11-12	`A.PE`	Preliminary Amendment	1	View
2025-11-12	`SPEC`	Specification	1	View
2025-11-12	`CLM`	Claims	31	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`371P`	Documents submitted with 371 (National Stage) Applications	1	View
2025-11-12	`N417`	Electronic Filing System Acknowledgment Receipt	4	View
2025-11-12	`N417.PYMT`	Electronic Fee Payment	2	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2025-11-12	`FRPR`	Certified Copy of Foreign Priority Application	92	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2025-11-12	`ABST`	Abstract	1	View
2025-11-12	`SPEC`	Specification	429	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View
2025-11-12	`CLM`	Claims	29	View
2025-11-12	`FRPR`	Certified Copy of Foreign Priority Application	264	View
2025-11-12	`P.N.101.CONV`	PCT/RO/101 - Request form for new International Application - Conventional	7	View
2025-11-12	`P.N.101.CONV`	PCT/RO/101 - Request form for new International Application - Conventional	1	View
2025-11-12	`P.306`	PCT/IB/306 - Notification of the Recording of a Change	1	View

Inventors

Inder BHAMRA Macclesfield, UNITED KINGDOM

Clifford D. JONES Macclesfield, UNITED KINGDOM

James RYAN Macclesfield, UNITED KINGDOM

Helen Elizabeth AYLOTT Macclesfield, UNITED KINGDOM

Daniel J. LENG Macclesfield, UNITED KINGDOM

Paula JACKSON Macclesfield, UNITED KINGDOM

Kelvin HO Macclesfield, UNITED KINGDOM

Attorneys & Agents of Record

CONNOR RAY Reg. 79155 Agent · FAEGRE DRINKER BIDDLE & REATH LLP

CLAUDIA SCHULTZE Reg. 60016 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

MARIO GAVIRIA Reg. 82680 Agent · LEYDIG, VOIT & MAYER, LTD.

STEVEN WIEMER Reg. 62897 Agent · FAEGRE BAKER DANIELS

NICHOLAS KUCHINSKI Reg. 76734 Attorney · FAEGRE DRINKER BIDDLE & REATH

PETER SISTARE Reg. 48183 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

FRANCIS DIGIOVANNI Reg. 37310 Attorney · DRINKER BIDDLE & REATH LLP

ANDREW SALMON Reg. 79894 Agent

JESSICA VAN DALEN Reg. 66707 Attorney · FAEGRE BAKER DANIELS LLP

GEOFFREY ZELLEY Reg. 66802 Attorney · DRINKER BIDDLE & REATH LLP

JAMES CARPENTER Reg. 62747 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

CATHERINE CALLAHAN Reg. 79770 Attorney · FAEGRE DRINKER BIDDLE & REATH

CHRISTOPHER BRUENJES Reg. 62941 Attorney · MEDLER FERRO WOODHOUSE & MILLS PLLC

THATCHER RAHMEIER Reg. 65734 Attorney · DRINKER BIDDLE & REATH LLP

JOHN SMITH Reg. 33818 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

KIRSTIN STOLL DEBELL Reg. 43164 Attorney · FAEGRE DRINKER BIDDLE & REATH, LLP

ROBERT STOLL Reg. 69299 Attorney · FAEGRE DRINKER BIDDLE & REATH

ROBERT CANNUSCIO Reg. 36469 Attorney · FAEGRE DRINKER BIDDLE AND REATH LLP

DEVIN STEIN Reg. 79807 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

ANDREW POUZESHI Reg. 67672 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

NOBUHISA YODA Reg. 75114 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

TIMOTHY SCULL Reg. 42137 Attorney · FAEGRE BAKER DANIELS

ADAM SCHLOSSER Reg. 66554 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

REEYA THAKRAR Reg. 76020 Attorney · DRINKER BIDDLE & REATH LLP

CARRIE BEYER Reg. 59195 Attorney · FAEGRE DRINKER BIDDLE & REATH LLP

Classification

USPC 514/210.21

C07D487/04 A61K31/519 A61K31/5377 A61K31/5386 A61K31/55 A61K31/551 A61K31/553 C07D519/00

Prosecution

Examiner: CENTRAL, DOCKET
Art Unit: OPAP
Customer No.: 123223
Docket No.: 221572-US-000076
Confirmation No.: 9659

Foreign Priority

2307077.4 · 2023-05-12 · UNITED KINGDOM

2319678.5 · 2023-12-20 · UNITED KINGDOM

No recorded assignments were found for this patent.

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Quick Facts

App. No.: 19/483,645
Filed: 2025-11-12
Examiner: CENTRAL, DOCKET
Art Unit: OPAP

External Links

USPTO Patent Center↗