SCALABLE PIPELINE FOR LOCAL ANCESTRY INFERENCE
Ancestry deconvolution includes obtaining unphased genotype data of an individual; phasing, using one or more processors, the unphased genotype data to generate phased haplotype data; using a learning machine to classify portions of the phased haplotype data as corresponding to specific ancestries respectively and generate initial classification results; and correcting errors in the initial classification results to generate modified classification results.
1 . An ancestry deconvolution system comprising:
one or more processors configured to:
obtain unphased genotype data of an individual;
phase the unphased genotype data to generate phased haplotype data;
use a learning machine to classify portions of the phased haplotype data as corresponding to specific ancestries respectively and generate initial classification results; and
correct errors in the initial classification results to generate modified classification results; and
one or more memories coupled with the one or more processors, configured to provide the one or more processors with instructions.