CHROMIUM CONTAINING COMPOSITIONS FOR IMPROVING HEALTH AND FITNESS
Administration of certain chromium complexes in combination with a starch provide unexpected benefits regarding increasing amino acid absorption, protein synthesis, exercise tolerance, lean muscle mass, skeletal muscle hypertrophy, muscle power, muscle endurance, muscle strength, FSR, and decreasing delayed onset muscle soreness, muscle protein breakdown, and fat mass.
1 - 62 . (canceled)
63 . A composition comprising chromium histidinate (CrHis), an essential amino acid, and a starch.
64 . The composition of claim 63 , wherein the essential amino acid is histidine.
65 . The composition of claim 63 , further comprising a pharmaceutically acceptable excipient.
66 . The composition of claim 63 , wherein the composition comprises from about 0.001% (w/w) to about 3% (w/w) of chromium.
67 . The composition of claim 66 , wherein the composition comprises from about 0.01% (w/w) to about 1% (w/w) of chromium.
68 . The composition of claim 63 , wherein the composition comprises from about 10 μg to about 2,000 μg of chromium.
69 . The composition of claim 68 , wherein the composition comprises from about 50 μg to about 1800 μg of chromium.
70 . The composition of claim 63 , wherein the composition comprises from about 100 mg to about 3000 mg of the starch.
71 . The composition of claim 70 , wherein the composition comprises from about 1500 mg to about 2000 mg of the starch.
72 . The composition of claim 63 , wherein the molar ratio of CrHis to the essential amino acid is from about 5:1 to about 1:10.
73 . The composition of claim 72 , wherein the molar ratio of CrHis to the essential amino acid is about 1:1.
74 . The composition of claim 63 , further comprising a compound selected from caffeine, creatine, creatine hydrochloride, creatine monohydrate, taurine, guarana, vitamin C, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B7, vitamin B9, and vitamin B12, or a combination of any of them.
75 . The composition of claim 63 , consisting essentially of CrHis, an essential amino acid, a starch, and a pharmaceutically acceptable excipient.
76 . A method for increasing muscle mass in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
77 . A method for treatment of muscle loss in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
78 . A method for increasing plasma levels of essential amino acids in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
79 . A method for increasing muscle uptake of branched chain amino acids in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
80 . A method of increasing a rate of muscle hypertrophy in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
81 . A method of increasing muscle protein synthesis in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.
82 . A method of decreasing delayed onset muscle soreness in a subject, comprising administering an effective amount of the composition of claim 63 to the subject.