Granted Patent
B2
US 8,017,113 · App. 11/222,745 · Granted Sep 13, 2011
Compositions and methods for diagnosing and treating an inflammation
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Abstract
A method of reducing an inflammatory response in a subject is provided. The method comprising providing to a subject in need thereof a therapeutically effective amount of an agent capable of reducing activity and/or expression of a scavenger receptor or of an effector thereof, thereby reducing the inflammatory response in the subject.
Claims (1)
1. A method of treating Crohn's disease in a subject, the method comprising providing to the subject in need thereof a therapeutically effective amount of an anti-SR-B1 antibody which reduces secretion of IL-12 or TNF-α or both and increases secretion of IL-10 in macrophages, thereby treating the Crohn's disease in the subject.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 28, 2018
From: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
To: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Reel/Frame 046493/0824 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 5, 2011
From: WILDBAUM, GIZI; ANUNU, RACHEL; ZOHAR, YANIV; NETZER, NIR
To: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
Reel/Frame 026855/0840 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 13, 2008
From: KARIN, NATHAN
To: RAPPAPORT FAMILY INSTITUTE FOR RESEARCH IN THE MEDICAL SCIENCES
Reel/Frame 020500/0977 →