IP Library Granted Patent US 8,073,550
Granted Patent B1
US 8,073,550 · App. 09/637,923 · Granted Dec 6, 2011

Method and apparatus for treating subcutaneous histological features

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Quick Facts
Patent No.
US 8,073,550
App. No.
09/637,923
Granted
Dec 6, 2011
Kind
B1
Abstract

A system and method for treating subcutaneous histological features without affecting adjacent tissues adversely employs microwave energy of selected power, frequency and duration to penetrate subcutaneous tissue and heat target areas with optimum doses to permanently affect the undesirable features. The frequency chosen preferentially interacts with the target as opposed to adjacent tissue, and the microwave energy is delivered as a short pulse causing minimal discomfort and side effects. By distributing microwave energy at the skin over an area and adjusting power and frequency, different conditions, such as hirsuitism and telangiectasia, can be effectively treated.

Claims (7)

1. A method of treating a targeted subcutaneous histological feature within a given depth range below a skin surface in the human body with microwave energy comprising the steps of selecting a microwave frequency in which the loss factor of the targeted subcutaneous histological feature is greater than the loss factor of tissue surrounding the targeted subcutaneous histological feature; and directing microwave energy at the selected frequency into the skin with a power density and for a duration sufficient to raise the temperature of the feature to a level resulting in a permanent change in the pathology of the targeted subcutaneous histological feature due to interaction of the electric field of the microwaves with the targeted subcutaneous histological feature tissue without resulting in a permanent change in the pathology of the tissue surrounding the targeted subcutaneous histological feature.

2. The method as set forth in claim 1 above, including the step of spreading the microwave energy with a distributed energy throughout an area at the depth range of the targeted subcutaneous histological feature.

3. The method as set forth in claim 2 above, including the further step of cooling tissue between the skin surface and the targeted subcutaneous histological feature during at least a portion of the treatment.

4. The method as set forth in claim 1 above, wherein the targeted subcutaneous histological feature comprises hair and the interaction of the electrical field of the microwaves with the hair induces heating of the hair to cause permanent destruction of the follicles.

5. The method as set forth in claim 4 above, wherein the targeted subcutaneous histological feature comprises hair roots approximately 5 mm below the skin surface, and wherein the method further includes the step of controlling power density and duration of the microwave energy to radiate the targeted subcutaneous histological feature with 10 to 15 Joules of energy.

6. The method as set forth in claim 1 above, wherein the targeted subcutaneous histological feature comprises blood vessels of about 0.1 mm diameter or greater and located 2 mm or less below the skin surface, and wherein the microwave energy thromboses blood in the blood vessels by raising blood temperature to in excess of 55° C.

7. The method as set forth in claim 6 above, wherein the microwave frequency is in a range of 10-20 GHz, the microwave energy is in a range of 20 to 30 Joules, and the duration is shorter than a time for thermal relaxation of blood vessels in the targeted subcutaneous histological feature.

Assignments (15)
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FUNDING IV TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0486 →
RELEASE OF SECURITY INTEREST Recorded Nov 22, 2022
From: MIDCAP FINANCIAL TRUST
To: SIENTRA, INC.; MIST HOLDINGS, INC.; MIST, INC.; MIST INTERNATIONAL, INC.
Reel/Frame 061983/0573 →
RELEASE OF SECURITY INTEREST (REVOLVING) Recorded Jun 22, 2021
From: MIDCAP FUNDING IV TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0001 →
RELEASE OF SECURITY INTEREST (TERM) Recorded Jun 22, 2021
From: MIDCAP FINANCIAL TRUST
To: MIRADRY HOLDINGS, INC.; MIRADRY, INC.; MIRADRY INTERNATIONAL, INC.
Reel/Frame 056648/0044 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049649/0450 →
SECURITY INTEREST Recorded Jul 2, 2019
From: SIENTRA, INC; MIRADRY HOLDINGS, INC.; MIRADRY, INC; MIRADRY INTERNATIONAL, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 049650/0001 →
SECURITY INTEREST Recorded Mar 13, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR TO MIDCAP FINANCIAL TRUST)
To: MIDCAP FUNDING IV TRUST, SUCCESSOR AGENT
Reel/Frame 048588/0123 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR LABS, INC.
To: MIRAMAR TECHNOLOGIES, INC.
Reel/Frame 045706/0690 →
CHANGE OF NAME Recorded May 3, 2018
From: MIRAMAR TECHNOLOGIES, INC.
To: MIRADRY, INC.
Reel/Frame 045707/0330 →
RELEASE OF SECURITY INTEREST Recorded Aug 18, 2017
From: OXFORD FINANCE LLC
To: MIRAMAR TECHNOLOGIES, INC. F/K/A MIRAMAR LABS, INC.
Reel/Frame 043331/0505 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043361/0130 →
SECURITY INTEREST Recorded Jul 28, 2017
From: SIENTRA, INC.; MIRAMAR LABS, INC.
To: MIDCAP FINANCIAL TRUST, AS AGENT
Reel/Frame 043362/0811 →
SECURITY INTEREST Recorded Mar 8, 2017
From: MIRAMAR TECHNOLOGIES, INC.
To: OXFORD FINANCE LLC
Reel/Frame 041510/0935 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 28, 2009
From: WALLACE, JAN
To: MIRAMAR LABS, INC.
Reel/Frame 023708/0092 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 28, 2009
From: MW MEDICAL, INC.
To: WALLACE, JAN
Reel/Frame 023699/0852 →