Methods and apparatus for treating anaphylaxis using electrical modulation
View Patent ↗Methods and devices for treating anaphylaxis, anaphylactic shock, bronchial constriction, and/or asthma include providing an electrical impulse to a selected region of the vagus nerve of a patient suffering from anaphylaxis to block and/or modulate nerve signals that would regulate the function of, for example, myocardial tissue, vasodilation/constriction and/or pulmonary tissue.
1. A device for treating bronchoconstriction in a patient comprising:
a power source;
an electrical impulse generator coupled to the power source;
one or more electrodes coupled to the electrical impulse generator; and
wherein the electrical impulse generator is operable to generate a signal sufficient to relax bronchial smooth muscle in the patient when a signal is applied via the one or more electrodes to a selected nerve in a parasympathetic nervous system.
2. The device of claim 1 further comprising a control unit in communication with the electrical impulse generator and coupled to the power source.
3. The device of claim 1 wherein the signal has a frequency of between about 1 to 3000 Hz.
4. The device of claim 3 wherein the frequency is between about 10 to 50 Hz.
5. The device of claim 3 wherein the frequency is between about 15 to 35 Hz.
6. The device of claim 1 wherein the signal has an amplitude of between about 1-12 volts.
7. The device of claim 1 wherein the signal has a pulsed-on time of between about 50 microseconds to about 800 microseconds.
8. The device of claim 1 wherein the signal has a pulsed-on time of between about 200 microseconds to about 400 microseconds.
9. The device of claim 1 wherein the one or more electrodes are implantable within the patient.
10. The device of claim 1 wherein the one or more electrodes are positionable exterior to the patient.
11. The device of claim 1 wherein the one or more electrodes are positionable to apply the signal to a vagus nerve in a neck of a patient.
12. The device of claim 1 wherein the one or more electrodes are positionable to apply the signal to a right branch of a vagus nerve in a neck of a patient.
13. A device for treating bronchoconstriction in a patient comprising:
a power source;
an impulse generator coupled to the power source;
one or more energy transmitters coupled to the impulse generator; and
wherein the impulse generator is operable to generate a signal sufficient to relax bronchial smooth muscle in the patient when energy is applied via the one or more energy transmitters to a selected nerve in a parasympathetic nervous system.
14. The device of claim 13 wherein the energy transmitters are electrodes.
15. The device of claim 13 further comprising a control unit in communication with the impulse generator and coupled to the power source.
16. The device of claim 13 wherein the signal has a frequency of between about 1 to 3000 Hz.
17. The device of claim 16 wherein the frequency is between about 10 to 50 Hz.
18. The device of claim 16 wherein the frequency is between about 15 to 35 Hz.
19. The device of claim 13 wherein the signal has an amplitude of between about 1 to 12 volts.
20. The device of claim 13 wherein the signal has a pulsed-on time of between about 50 to 800 microseconds.
21. The device of claim 13 wherein the signal has a pulsed-on time of between about 200 to 400 microseconds.
22. The device of claim 13 wherein the one or more energy transmitters are implantable within the patient.
23. The device of claim 13 wherein the one or more energy transmitters are postionable exterior to the patient.
24. The device of claim 13 wherein the one or more energy transmitters are positionable to apply the signal to a vagus nerve in the neck of the patient.
25. The device of claim 13 wherein the one or more energy transmitters are positionable to apply the signal to a right branch of a vagus nerve in the neck of the patient.