Cartridge for automatic measurement and measuring device using the same
View Patent ↗An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge. The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.
1. A cartridge, used by being set in a measuring device comprising a dispensing portion which comprises a pipette tip dispensing a reagent and/or a sample to each well on the cartridge, and automatically measuring a component in a sample, comprising:
at least a heat-treatment well configured to perform heat treatment of the sample;
a reaction well configured to produce a reaction between the component to be measured in the sample and a material specifically reacting therewith;
a reagent-containing well containing a reagent required for measurement; and
a diluting solution-containing well containing diluting solution for diluting the sample and/or a washing well containing washing solution for washing a reaction product produced by the reaction,
wherein the reagent-containing well, the diluting solution-containing well, and/or the washing well is sealed with a seal,
wherein information selected from the group consisting of information on a sample, information on an analyzing item, information on reagent management, and information on a calibration curve used for measurement is recorded on the seal, and
wherein the record of the information is configured so as to be broken by breaking the seal with the leading end of the pipette tip when the cartridge is used.
2. The cartridge according to claim 1 , wherein the information is recorded with a bar code.
3. The cartridge according to claim 1 , wherein the seal is an aluminum laminate foil or a plastic film.
4. The cartridge according to claim 1 , wherein the reagent-containing well contains a labeled antibody solution or a magnetic particle solution, and the depth of the reagent-containing well is smaller than the depth of the diluting solution-containing well and/or the depth of the washing well.
5. The cartridge according to claim 4 , wherein the depth of the labeled antibody solution and/or the depth of the magnetic particle solution is smaller than the depth of the diluting solution and/or the depth of the washing solution.
6. A cartridge, used by being set in a device comprising a perforating mechanism, and automatically measuring a component in a sample, comprising:
at least a heat-treatment well configured to perform heat treatment of the sample;
a reaction well configured to produce a reaction between the component to be measured in the sample and a material specifically reacting therewith;
a reagent-containing well containing a reagent required for measurement; and
a diluting solution-containing well containing diluting solution for diluting the sample and/or a washing well containing washing solution for washing a reaction product produced by the reaction,
wherein the reagent-containing well, the diluting solution-containing well, and/or the washing well is sealed with a seal,
wherein information selected from the group consisting of information on a sample, information on an analyzing item, information on reagent management, and information on a calibration curve used for measurement is recorded on the seal, and
wherein the record of the information is configured so as to be broken by breaking the seal with the perforating mechanism when the cartridge is used.
7. The cartridge according to claim 6 , wherein the information is recorded with a bar code.
8. The cartridge according to claim 6 , wherein the seal is an aluminum laminate foil or a plastic film.
9. The cartridge according to claim 6 , wherein the reagent-containing well contains a labeled antibody solution or a magnetic particle solution, and the depth of the reagent-containing well is smaller than the depth of the diluting solution-containing well and/or the depth of the washing well.
10. The cartridge according to claim 9 , wherein the depth of the labeled antibody solution and/or the depth of the magnetic particle solution is smaller than the depth of the diluting solution and/or the depth of the washing solution.
11. A method measuring a component in a sample using the cartridge of claim 1 , and a measuring device comprising at least a cartridge-accommodating portion configured to accommodate the cartridge, a dispensing portion configured to dispense the reagent and/or the sample to each well on the cartridge accommodated in the cartridge-accommodating portion wherein the dispensing portion comprises a pipette tip, a measuring portion configured to measure a reaction product on the cartridge accommodated in the cartridge-accommodating portion, and a temperature controlling portion capable of controlling at least the heat-treatment well and the reaction well on the cartridge to desired temperatures comprising:
breaking the record of the information by breaking the seal with the leading end of the pipette tip when the cartridge is used.
12. The method according to claim 11 , wherein the information is recorded with a bar code, wherein the measuring device further comprises a barcode recognizing mechanism, and the method further comprises:
recognizing the barcode by the barcode recognizing mechanism; and
subsequently breaking the record of the information on barcode by breaking the seal with the leading end of the tip.
13. A method measuring a component in a sample using the cartridge of claim 6 , and a measuring device comprising at least a cartridge-accommodating portion configured to accommodate the cartridge, a dispensing portion configured to dispense the reagent and/or the sample to each well on the cartridge accommodated in the cartridge-accommodating portion, a measuring portion configured to measure a reaction product on the cartridge accommodated in the cartridge-accommodating portion, a temperature controlling portion capable of controlling at least the heat-treatment well and the reaction well on the cartridge to desired temperatures, and a perforating mechanism for perforating the seal, the method comprising:
breaking the record of the information by breaking the seal with the perforating mechanism when the cartridge is used.
14. The method according to claim 13 , wherein the information is recorded with a bar code, wherein the measuring device further comprises a barcode recognizing mechanism, and the method further comprises:
recognizing the barcode by the barcode recognizing mechanism; and
subsequently breaking the record of the information on the barcode by breaking the seal with the perforating mechanism.