IP Library Granted Patent US 8,758,447
Granted Patent B2
US 8,758,447 · App. 12/494,887 · Granted Jun 24, 2014

Device and method for repair of urological structures

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Quick Facts
Patent No.
US 8,758,447
App. No.
12/494,887
Granted
Jun 24, 2014
Kind
B2
Abstract

A tissue engineering construct made from a nonwoven fabric. The fabric is made from first and second staple fibers. The first staple fibers are made from a first biocompatible, bioabsorbable material, and the second staple fibers are made from a second biocompatible, bioabsorbable material. The first material has a melting temperature lower than the second material. The fabric is formed into a three-dimensional construct suitable for the repair of urinary tract structures.

Claims (11)

1. A method of repairing a urinary structure comprising the steps of:

A. providing an acellular repair device comprising:

a nonwoven fabric, wherein said fabric comprises first and second staple fibers,

wherein the first staple fibers comprise a first biocompatible, bioabsorbable material and the second staple fibers comprise a second biocompatible, bioabsorbable material,

wherein the first biocompatible bioabsorbable material is poly(p-dioxanone) and the second biocompatible material comprises a polymer selected from the group consisting of poly(glycolide) and poly(glycolide-co-lactide), and

wherein said fabric is formed into a three-dimensional shape having an opening and an internal cavity wherein the opening is in communication with the cavity and the cavity is suitable for urinary bladder repair; and,

B. attaching the opening on the acellular repair device to a urinary bladder structure.

2. The method of claim 1 , wherein in the shape is selected from the group consisting of spheres, hemispheres, prisms, cylinders, cones, and combinations thereof.

3. The method of claim 1 , wherein the nonwoven fabric comprises about 50% to about 75% by weight of the first biocompatible, bioabsorbable material.

4. The method of claim 1 , wherein the first and second staple fibers have a length from about 0.75 inches to about 2.0 inches.

5. The method of claim 1 , comprising the additional steps of performing a partial bladder cystectomy and attaching the urinary repair device to a remaining section of the bladder.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 9, 2013
From: ADVANCED TECHNOLOGIES AND REGNERATIVE MEDICINE, LLC
To: ETHICON, INC.
Reel/Frame 029595/0417 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 19, 2012
From: ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC
To: ETHICON, INC.
Reel/Frame 029496/0269 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 11, 2009
From: SHETTY, DHANURAJ S.; DONNERS, JACKIE J.; DHANARAJ, SRIDEVI; GEESIN, JEFFREY C.
To: ADVANCED TECHNOLOGIES AND REGENERATIVE MEDICINE, LLC
Reel/Frame 023216/0973 →