IP Library Granted Patent US 10,463,598
Granted Patent B2
US 10,463,598 · App. 15/377,804 · Granted Nov 5, 2019

Compositions and kits for the removal of irritating compounds from bodily surfaces

View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,463,598
App. No.
15/377,804
Granted
Nov 5, 2019
Kind
B2
Abstract

The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.

Claims (37)

1. An aqueous composition for cleansing capsaicin from a bodily surface comprising:

a) about 80 to about 99 percent w/w polyethylene glycol (PEG); and

b) about 0.1 to about 4.0 percent w/w polyacrylate thickening agent,

wherein the aqueous composition has a viscosity of between 100 to 8000 cps.

2. The aqueous composition of claim 1 , comprising:

about 84 to about 94 percent w/w polyethylene glycol (PEG).

3. The aqueous composition of claim 2 , further comprising a stabilizer.

4. The aqueous composition of claim 3 , further comprising a cooling agent.

5. The aqueous composition of claim 3 , comprising:

a) about 87 to about 91 percent w/w polyethylene glycol (PEG);

b) about 0.3 to about 2 percent w/w polyacrylate thickening agent;

c) about 0.01 to about 0.03 percent w/w butylated hydroxyanisole;

d) about 0.02 to about 0.2 percent w/w edetate sodium; and

e) the balance water; wherein the aqueous composition is at a pH of about 7.0 to about 7.7.

6. The aqueous composition of claim 5 , comprising:

a) about 89.08 percent w/w PEG 300;

b) about 1.0 percent w/w polyacrylate thickening agent;

c) about 0.02 percent w/w butylated hydroxyanisole;

d) about 0.1 percent w/w disodium edetate; and

e) the balance water; wherein the aqueous composition is at a pH of about 7.5.

7. The aqueous composition of claim 1 , having a pH between about 7.0 and about 7.7.

8. The aqueous composition of claim 2 , comprising about 90 percent w/w polyethylene glycol (PEG).

9. The aqueous composition of claim 8 , further comprising:

i) about 0.1 to about 2.0 percent w/w polyacrylate thickening agent; and

ii) the balance water; wherein the aqueous composition is at a pH between about 7.0 and about 7.7.

10. The aqueous composition of claim 1 , wherein the PEG is PEG 200 to PEG 600.

11. The aqueous composition of claim 1 , in which capsaicin has a solubility of at least about 10 to 25 percent w/w.

12. The aqueous composition of claim 11 , in which capsaicin has a solubility of about 10 percent w/w.

13. The aqueous composition of claim 11 , in which capsaicin has a solubility of about 20 percent w/w.

14. The aqueous composition of claim 11 , in which capsaicin has a solubility of about 25 percent w/w.

15. The aqueous composition of claim 1 , which is a surfactant-free gel.

16. The aqueous composition of claim 1 , wherein the viscosity is between 4000 cps to 8000 cps.

17. The aqueous composition of claim 16 , wherein the viscosity is between 4000 to 5000 cps.

18. The aqueous composition of claim 1 , wherein the viscosity is between 2000 to 5000 cps.

19. The aqueous composition of claim 1 , wherein the viscosity is between 100 to 1000 cps.

20. The aqueous composition of claim 1 , which is substantially free of particulates.

21. The aqueous composition of claim 1 , wherein the polyacrylate thickening agent is an acrylic acid/ethylacrylate copolymer or a carboxyvinyl polymer.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 15, 2019
From: GRÜNENTHAL GMBH
To: AVERITAS PHARMA INC.
Reel/Frame 050065/0189 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2019
From: ACORDA THERAPEUTICS, INC.
To: GRÜNENTHAL GMBH
Reel/Frame 049260/0707 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2017
From: DOW PHARMACEUTICAL SCIENCES
To: NEUROGESX, INC.
Reel/Frame 044236/0404 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2017
From: WILCOX, ALLAN L.; BLEY, KEITH R.; JAMIESON, GENE C.; MUHAMMAD, NAWEED
To: NEUROGESX, INC.
Reel/Frame 044236/0442 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2017
From: ANGEL, ARTURO S.; LITLE, LARRY W.
To: DOW PHARMACEUTICAL SCIENCES
Reel/Frame 044236/0542 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 28, 2017
From: NEUROGESX, INC.
To: ACORDA THERAPEUTICS, INC.
Reel/Frame 044648/0252 →