IP Library Granted Patent US 10,695,004
Granted Patent B2
US 10,695,004 · App. 16/000,529 · Granted Jun 30, 2020

Activity-dependent multi-mode physiological sensor

Inventors: Paul J. Gaudet (Dracut, MA); Thomas J. Quinlan, III (Sturbridge, MA); Jerry Zhang (Westborough, MA); Norbert Ohlenbusch (Andover, MA); Thomas P. Blackadar (Hanson, MA); David P. Monahan (West Chester, PA)
Assignee: LumiraDX UK, Ltd.
A61B5/7214A61B5/04087A61B5/1118G16H20/40G16H50/20A61B2560/0412A61B2562/0219G01C22/006G16H10/60G16H40/67
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Quick Facts
Patent No.
US 10,695,004
App. No.
16/000,529
Granted
Jun 30, 2020
Kind
B2
Abstract

Disclosed are systems and methods for using one or more light sources and associated photodetectors to determine different physiological parameters of a subject based on the subject's activity state. A processor may, for example, be configured to determine, based at least in part on data received from an accelerometer at a first time, that a first physiological parameter of the subject is to be determined, to cause the light source(s) to operate in a first manner and process signals from the photodetector(s) to determine the first physiological parameter, to determine, based at least in part on data received from the accelerometer at a second time, that a second physiological parameter of the subject is to be determined, and to cause the light source(s) to operate in a second manner and process signals from the photodetector(s) to determine the second physiological parameter.

Claims (43)

1. A system that is configured to be supported by a subject, the system comprising:

a processor;

an accelerometer;

at least one light source configured to interrogate a region of the subject; and

at least one photodetector configured to receive radiation from the at least one light source which is reflected from or transmitted through the region of the subject;

wherein the processor is configured to:

determine, based at least in part on data received from the accelerometer at a first time, that a first physiological parameter of the subject is to be determined,

in response to determining that the first physiological parameter is to be determined, cause the at least one light source to operate and process signals from the at least one photodetector to determine the first physiological parameter,

determine, based at least in part on data received from the accelerometer at a second time, that a second physiological parameter of the subject, which is different than the first physiological parameter, is to be determined, and

in response to determining that the second physiological parameter is to be determined, cause the at least one light source to operate and process signals from the at least one photodetector to determine the second physiological parameter.

2. The system of claim 1 , wherein the processor is further configured to:

cause the at least one light source to operate in a first manner to determine the first physiological parameter; and

cause the at least one light source to operate in a second manner, which is different than the first manner, to determine the second physiological parameter.

3. The system of claim 1 , wherein the first physiological parameter comprises a blood oxygenation level of the subject.

4. The system of claim 3 , wherein the second physiological parameter comprises a heart rate of the subject.

5. The system of claim 3 , wherein the second physiological parameter comprises a blood glucose level of the subject.

6. The system of claim 3 , wherein the second physiological parameter comprises at least one feature of a plethysmography waveform.

7. The system of claim 2 , wherein the first physiological parameter comprises a heart rate of the subject.

8. The system of claim 7 , wherein the second physiological parameter comprises a blood glucose level of the subject.

9. The system of claim 7 , wherein the second physiological parameter comprises at least one feature of a plethysmography waveform.

10. The system of claim 1 , wherein:

the first physiological parameter comprises a blood glucose level of the subject, and the second physiological parameter comprises at least one feature of a plethysmography waveform.

11. A method, comprising:

interrogating a region of a subject with light emitted from at least one light source;

receiving, with at least one photodetector, radiation from the at least one light source which is reflected from or transmitted through the region of the subject; and

using a processor to:

determine, based at least in part on data received from an accelerometer at a first time, that a first physiological parameter of the subject is to be determined,

in response to determining that the first physiological parameter is to be determined, cause the at least one light source to operate and process signals from the at least one photodetector to determine the first physiological parameter,

determine, based at least in part on data received from the accelerometer at a second time, that a second physiological parameter of the subject, which is different than the first physiological parameter, is to be determined, and

in response to determining that the second physiological parameter is to be determined, cause the at least one light source to operate and process signals from the at least one photodetector to determine the second physiological parameter.

12. The method of claim 11 , wherein:

using the processor to cause the at least one light source to operate to determine the first physiological parameter further comprises using the processor to cause the at least one light source to operate in a first manner; and

using the processor to cause the at least one light source to operate to determine the second physiological parameter further comprises using the processor to cause the at least one light source to operate in a second manner, which is different than the first manner, to determine the second physiological parameter.

13. The method of claim 11 , wherein the first physiological parameter comprises a blood oxygenation level of the subject.

14. The method of claim 13 , wherein the second physiological parameter comprises a heart rate of the subject.

15. The method of claim 13 , wherein the second physiological parameter comprises a blood glucose level of the subject.

16. The method of claim 13 , wherein the second physiological parameter comprises at least one feature of a plethysmography waveform.

17. The method of claim 11 , wherein the first physiological parameter comprises a heart rate of the subject.

18. The method of claim 17 , wherein the second physiological parameter comprises a blood glucose level of the subject.

19. The method of claim 17 , wherein the second physiological parameter comprises at least one feature of a plethysmography waveform.

20. The method of claim 11 , wherein:

the first physiological parameter comprises a blood glucose level of the subject; and

the second physiological parameter comprises at least one feature of a plethysmography waveform.

Assignments (6)
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY, RECORDED ON MARCH 30, 2021 AT REEL/FRAME 055850/0771 Recorded Aug 5, 2024
From: BIOPHARMA CREDIT PLC, AS COLLATERAL AGENT
To: LUMIRADX INTERNATIONAL LTD; LUMIRADX UK LTD
Reel/Frame 068327/0149 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded Mar 30, 2021
From: LUMIRADX INTERNATIONAL LTD; LUMIRADX UK LTD
To: BIOPHARMA CREDIT PLC
Reel/Frame 055850/0771 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 4, 2020
From: QUINLAN, THOMAS J.; GAUDET, PAUL J.; OHLENBUSCH, NORBERT; ZHANG, JERRY; OLIVER, STEVEN R.; BLACKADAR, THOMAS P.; MONAHAN, DAVID P.
To: FITLINXX, INC.
Reel/Frame 052562/0084 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 4, 2020
From: FITLINXX, INC.
To: LUMIRA LTD.
Reel/Frame 052562/0094 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 4, 2020
From: FITLINXX, INC.
To: LUMIRA LTD.
Reel/Frame 052562/0154 →
CHANGE OF NAME Recorded May 4, 2020
From: LUMIRA LTD
To: LUMIRADX UK LTD
Reel/Frame 052562/0167 →
Cited By (4)
US 12,484,787 US 12,502,080 US 12,588,820 US 12,599,305