IP Library › Granted Patent US 10,696,682
Granted Patent B2
US 10,696,682 · App. 16/226,430 · Granted Jun 30, 2020

CDK inhibitors

Inventors: Francis X. Tavares (Durham, NC); Jay Copeland Strum (Hillsborough, CT)
Assignee: G1 Therapeutics, Inc.
C07D487/14A61K31/499C07D487/20C07D498/14C07D519/00
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Quick Facts
Patent No.
US 10,696,682
App. No.
16/226,430
Granted
Jun 30, 2020
Kind
B2
Abstract

Compounds of formulae I, II or III, and pharmaceutically acceptable salts thereof, are useful as CDK inhibitors.

Claims (13)

1. A pharmaceutical composition comprising a pharmaceutically acceptable carrier and an effective amount of a compound of structure:

or a pharmaceutically acceptable salt thereof, wherein the pharmaceutical composition is a solid dosage form.

2. The pharmaceutical composition of claim 1 , wherein the compound is not in the form of a salt.

3. The pharmaceutical composition of claim 1 , wherein the dosage form is in a tablet.

4. The pharmaceutical composition of claim 1 , wherein the dosage form is in a pill.

5. The pharmaceutical composition of claim 1 , wherein the dosage form is in a capsule.

6. The pharmaceutical composition of claim 1 , wherein the dosage form is a tablet.

7. The pharmaceutical composition of claim 1 , wherein the dosage form is a pill.

8. The pharmaceutical composition of claim 2 , wherein the dosage form is in a tablet.

9. The pharmaceutical composition of claim 2 , wherein the dosage form is in a pill.

10. The pharmaceutical composition of claim 2 , wherein the dosage form is in a capsule.

11. The pharmaceutical composition of claim 2 , wherein the dosage form is a tablet.

12. The pharmaceutical composition of claim 2 , wherein the dosage form is a pill.

Assignments (9)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2025
From: PHARMACOSMOS THERAPEUTICS, INC.
To: PHARMACOSMOS A/S
Reel/Frame 071018/0280 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 23, 2025
From: PHARMACOSMOS A/S
To: PHARMACOSMOS HOLDING A/S
Reel/Frame 071018/0238 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 22, 2024
From: G1 THERAPEUTICS, INC.
To: PHARMACOSMOS A/S
Reel/Frame 069371/0820 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 22, 2024
From: PHARMACOSMOS A/S
To: PHARMACOSMOS HOLDING A/S
Reel/Frame 069371/0832 →
RELEASE OF SECURITY INTEREST IN INTELLECTUAL PROPERTY Recorded Sep 19, 2024
From: HERCULES CAPITAL, INC., AS COLLATERAL AGENT
To: G1 THERAPEUTICS, INC.
Reel/Frame 068996/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 29, 2021
From: TAVARES, FRANCIS X.
To: G1 THERAPEUTICS, INC.
Reel/Frame 055746/0368 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 25, 2021
From: STRUM, JAY C.
To: G1 THERAPEUTICS, INC.
Reel/Frame 055725/0743 →
INTELLECTUAL PROPERTY SECURITY AGREEMENT Recorded May 29, 2020
From: G1 THERAPEUTICS, INC.
To: HERCULES CAPITAL, INC., AS COLLATERAL AGENT
Reel/Frame 052795/0074 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 25, 2020
From: TAVARES, FRANCIS X.; STRUM, JAY C.
To: G1 THERAPEUTICS, INC.
Reel/Frame 051922/0499 →