IP Library Granted Patent US 11,090,421
Granted Patent B2
US 11,090,421 · App. 16/203,104 · Granted Aug 17, 2021

Systems and methods for batch sorbent material reuse

Inventors: Yuanpang Samuel Ding (Long Grove, IL); Rosa Hung-Chen Yeh (Libertyville, IL); Cristian Adolfo Menzel Bueno (Gurnee, IL); Ieng Kin Lao (Taipa, MO)
Assignees: Baxter International Inc.; Baxter Healthcare SA
A61M1/1696B01J20/0211B01J20/0292B01J20/06
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Quick Facts
Patent No.
US 11,090,421
App. No.
16/203,104
Granted
Aug 17, 2021
Kind
B2
Abstract

Methods, sorbent cartridges and cleaning devices are disclosed for refurbishing sorbent materials. In one implementation among multiple implementations, a medical fluid delivery method includes: providing a sorbent cartridge including H + ZP within a casing for a treatment; and after the treatment, refurbishing the H + ZP while maintained within the casing via (i) regenerating the non-disinfected H + ZP by flowing an acid solution through the casing, (ii) rinsing the regenerated H + ZP while maintained within the casing, (iii) disinfecting the regenerated and rinsed H + ZP by flowing a disinfecting agent through the casing, and (iv) rinsing the regenerated and disinfected H + ZP while maintained within the casing. Multiple batch sorbent refubishing implementations are also disclosed.

Claims (48)

1. A medical fluid delivery method comprising:

providing a sorbent cartridge including zirconium phosphate (“ZP”) or zirconium oxide (“ZO”) for a treatment; and

after the treatment, refurbishing the ZP or ZO via the steps of

regenerating the non-disinfected ZP or ZO using an acid solution,

disinfecting the regenerated ZP or ZO using a disinfecting agent,

at least one of washing or filtering the regenerated and disinfected ZP or ZO,

titrating the washed or filtered ZP or ZO until a desired pH is reached in a titrated ZP or ZO,

at least one of washing or filtering the titrated ZP or ZO until a desired conductivity is reached in a rewashed or refiltered ZP or ZO,

drying the rewashed or refiltered ZP or ZO, and

sieving the dried ZP or ZO.

2. The medical fluid delivery method of claim 1 , wherein at least one of (a) the acid solution is HCl, H 2 SO 4 , H 3 PO 4 , HNO 3 or acetic acid or (b) the disinfecting agent (i) is sodium based, such as including NaOCl, (ii) is hydrogen based, such as including HOC 1 , or (iii) includes isopropyl alcohol (“IPA”).

3. The medical fluid delivery method of claim 1 , wherein the desired pH is between and including 5.5 to 8.5.

4. The medical fluid delivery method of claim 1 , wherein the desired conductivity is below 50 μS/cm.

5. The medical fluid delivery method of claim 1 , wherein refurbishing the ZP or ZO includes combining ZP or ZO removed from multiple sorbent cartridges before regeneration.

6. A medical fluid delivery method comprising:

providing a sorbent cartridge including zirconium phosphate (“ZP”) or zirconium oxide (“ZO”) for a treatment; and

after the treatment, refurbishing the ZP or ZO via

regenerating the non-disinfected ZP or ZO using an acid solution,

disinfecting the regenerated ZP or ZO using a disinfecting agent,

at least one of washing or filtering the regenerated and disinfected ZP or ZO,

drying the washed or filtered ZP or ZO, and

sieving the dried ZP or ZO.

7. The medical fluid delivery method of claim 6 , wherein at least one of (a) the acid solution is HCl, H 2 SO 4 , H 3 PO 4 , HNO 3 or acetic acid or (b) the disinfecting agent (i) is sodium based, such as including NaOCl, (ii) is hydrogen based, such as including HOCl, or (iii) includes isopropyl alcohol (“IPA”).

8. The medical fluid delivery method of claim 6 , wherein refurbishing the ZP or ZO includes combining ZP or ZO removed from multiple sorbent cartridges before regeneration.

9. A medical fluid delivery method comprising:

providing a sorbent cartridge including zirconium phosphate (“ZP”) or zirconium oxide (“ZO”) for a treatment; and

after the treatment, refurbishing the ZP or ZO via

regenerating the non-disinfected ZP or ZO using a sodium based alkaline solution or a sodium salt solution,

disinfecting the regenerated ZP or ZO using a disinfecting agent,

at least one of washing or filtering the regenerated and disinfected ZP or ZO,

titrating the washed or filtered ZP or ZO until a desired pH is reached in a titrated ZP or ZO,

at least one of washing or filtering the titrated ZP or ZO until a desired conductivity is reached in a rewashed or refiltered ZP or ZO,

drying the rewashed or refiltered ZP or ZO, and

sieving the dried ZP or ZO.

10. The medical fluid delivery method of claim 9 , wherein at least one of (a) the sodium based alkaline solution or a sodium salt solution is NaOH, NaHCO 3 , Na 2 CO 3 or NaCl or (b) the disinfecting agent (i) is sodium based, such as including NaOCl, (ii) is hydrogen based, such as including HOCl, or (iii) includes isopropyl alcohol (“IPA”).

11. The medical fluid delivery method of claim 9 , wherein the desired pH is between and including 5.5 to 8.5.

12. The medical fluid delivery method of claim 9 , wherein the desired conductivity is below 50 μS/cm.

13. The medical fluid delivery method of claim 9 , wherein refurbishing the ZP or ZO includes combining ZP or ZO removed from multiple sorbent cartridges before regeneration.

14. A medical fluid delivery method comprising:

providing a sorbent cartridge including zirconium phosphate (“ZP”) or zirconium oxide (“ZO”) for a treatment; and

after the treatment, refurbishing the ZP or ZO via

regenerating the non-disinfected ZP or ZO using a sodium based alkaline solution or a sodium salt solution,

disinfecting the regenerated ZP or ZO using a disinfecting agent,

at least one of washing or filtering the regenerated and disinfected ZP or ZO,

drying the washed or filtered ZP or ZO, and

sieving the dried ZP or ZO.

15. The medical fluid delivery method of claim 14 , wherein at least one of (a) the sodium based alkaline solution or a sodium salt solution is NaOH, NaHCO 3 , Na 2 CO 3 or NaCl or (b) the disinfecting agent (i) is sodium based, such as including NaOCl, (ii) is hydrogen based, such as including HOCl, or (iii) includes isopropyl alcohol (“IPA”).

16. The medical fluid delivery method of claim 14 , wherein refurbishing the ZP or ZO includes combining ZP or ZO removed from multiple sorbent cartridges before regeneration.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER INTERNATIONAL INC.
To: VANTIVE US HEALTHCARE LLC
Reel/Frame 073413/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 31, 2025
From: BAXTER HEALTHCARE SA
To: VANTIVE HEALTH GMBH
Reel/Frame 073438/0790 →
SECURITY INTEREST Recorded Jan 31, 2025
From: VANTIVE US HEALTHCARE LLC; GAMBRO RENAL PRODUCTS, INC.
To: ARES CAPITAL CORPORATION
Reel/Frame 070076/0701 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2019
From: DING, YUANPANG SAMUEL; YEH, ROSA HUNG-CHEN; MENZEL BUENO, CRISTIAN ADOLFO
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 050012/0364 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2019
From: LAO, LENG KIN
To: BAXTER HEALTHCARE (SUZHOU) CO., LTD.
Reel/Frame 050014/0233 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2019
From: BAXTER HEALTHCARE (SUZHOU) CO., LTD.
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 050017/0828 →