IP Library Granted Patent US 11,618,751
Granted Patent B1
US 11,618,751 · App. 17/704,983 · Granted Apr 4, 2023

Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives

Inventor: Stéphane Dorich (Pointe-Claire, CA)
Assignee: Ventus Therapeutics U.S., Inc.
C07D471/04A61P25/28
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Quick Facts
Patent No.
US 11,618,751
App. No.
17/704,983
Granted
Apr 4, 2023
Kind
B1
Abstract

The present disclosure relates to inhibitors of NLRP3 useful in the treatment of diseases and disorders inhibited by said protein.

Claims (10)

1. A compound selected from the group consisting of:

or a pharmaceutically acceptable salt of any of the foregoing.

2. A compound of formula:

or a pharmaceutically acceptable salt thereof.

3. A compound of formula:

or a pharmaceutically acceptable salt thereof.

4. A compound of formula:

or a pharmaceutically acceptable salt thereof.

5. A compound of formula:

or a pharmaceutically acceptable salt thereof.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2023
From: DORICH, STÉPHANE; CHEFSON, AMANDINE
To: VENTUS THERAPEUTICS, INC.
Reel/Frame 065587/0738 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2023
From: VENTUS THERAPEUTICS, INC.
To: VENTUS THERAPEUTICS U.S., INC.
Reel/Frame 065587/0909 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 2, 2022
From: DORICH, STÉPHANE; CHEFSON, AMANDINE
To: VENTUS THERAPEUTICS U.S., INC.
Reel/Frame 060697/0918 →
Cited By (8)
US 12,195,460 US 12,281,112 US 12,312,350 US 12,312,351 US 12,331,048 US 12,398,136 US 12,410,167 US 12,441,728