IP Library › Granted Patent US 11,638,708
Granted Patent B2
US 11,638,708 · App. 16/240,389 · Granted May 2, 2023

Method of treatment of aggression

Inventor: Christopher D. Breder (Bethesda, MD)
Assignee: Supernus Pharmaceuticals, Inc.
A61K31/5377A61K31/00
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Quick Facts
Patent No.
US 11,638,708
App. No.
16/240,389
Granted
May 2, 2023
Kind
B2
Abstract

The invention comprises a method of treatment of aggression and similar behavioral syndromes, such as impulsivity and irritability, by a pharmaceutical agent exhibiting combined D2 and D5 antagonistic activity.

Claims (6)

1. A method of treating a behavioral syndrome selected from impulsivity and irritability in a mammalian subject diagnosed with a single condition selected from the group consisting of bipolar disorder and post-traumatic stress disorder comprising administering to the subject a pharmaceutical agent exhibiting combined D2 and D5 antagonistic activity;

wherein the pharmaceutical agent is molindone.

2. The method of claim 1 , wherein the behavioral syndrome is impulsivity.

3. The method of claim 1 , wherein the behavioral syndrome is irritability.

4. The method of claim 1 , wherein the agent is administered in a dose range of from 10 mg/day to 200 mg/day.

5. The method of claim 1 , wherein said mammalian subject is a child.