IP Library › Granted Patent US 12,434,012
Granted Patent B1
US 12,434,012 · App. 19/064,379 · Granted Oct 7, 2025

Medicament delivery device

Inventors: Alexander Hee-Hanson (Melbourn, GB); Thomas Lever (Melbourn, GB); Michael Parrott (Melbourn, GB); Robert Wilson (Melbourn, GB); Haiming Wu (Weston, MA)
Assignee: Genzyme Corporation
A61M5/3202A61M5/31501
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Quick Facts
Patent No.
US 12,434,012
App. No.
19/064,379
Granted
Oct 7, 2025
Kind
B1
Abstract

A medicament delivery device is described. The device includes a body comprising a proximal end and a distal end; a needle for injecting medicament; an actuation member moveable relative to the body for actuating the device; a lock ring configured to rotate relative to the body between a first position in which the actuation member is not permitted to move relative to the body, and a second position in which the actuation member is permitted to move relative to the body; and a cap arrangeable in a capped position in which the cap abuts with and conceals the distal end of the body to conceal the needle; wherein when the cap is in the capped position the lock ring is in a first state in which the lock ring is in the first position and is not permitted to rotate towards the second position; and wherein moving the cap in a distal direction away from the distal end of the body along the longitudinal axis away from the capped position causes the lock ring to be in a second state in which the lock ring is permitted to rotate from the first position towards the second position.

Claims (28)

1. A medicament delivery device comprising:

a body comprising a proximal end and a distal end defining a longitudinal axis;

a needle for injecting medicament;

an actuation member moveable relative to the body along the longitudinal axis for actuating the medicament delivery device;

a lock ring configured to rotate relative to the body about the longitudinal axis between a first position in which the actuation member is not permitted to move along the longitudinal axis relative to the body, and a second position in which the actuation member is permitted to move along the longitudinal axis relative to the body; and

a cap arrangeable in a capped position in which the cap abuts with and conceals the distal end of the body to conceal the needle;

wherein the medicament delivery device is configured such that (i) when the cap is in the capped position, the lock ring is in a first state in which the lock ring is in the first position and is not permitted to rotate towards the second position, and (ii) moving the cap in a distal direction away from the distal end of the body along the longitudinal axis away from the capped position causes the lock ring to be in a second state in which the lock ring is permitted to rotate from the first position towards the second position.

2. The medicament delivery device of claim 1 , wherein the medicament delivery device is configured such that when the lock ring is in the first state the lock ring is not permitted to rotate about the longitudinal axis relative to the body, and when the lock ring is in the second state the lock ring is permitted to rotate about the longitudinal axis relative to the body.

3. The medicament delivery device of claim 1 , wherein the actuation member is moveable relative to the body along the longitudinal axis in the distal direction from the first position, to the second position for dispensing medicament from the needle.

4. The medicament delivery device of claim 3 , wherein the medicament delivery device further comprises a first biasing member configured to bias the actuation member towards the first position.

5. The medicament delivery device of claim 3 , wherein the needle is moveable along the longitudinal axis relative to the body between: a retracted position in which the needle is arranged inside the body, and an extended position for delivering medicament in which at least a portion of the needle protrudes from the distal end of the body, and wherein the medicament delivery device is configured such that moving the actuation member from the first position to the second position along the distal direction causes the needle to be moved from the retracted position to the extended position.

6. The medicament delivery device of claim 1 , wherein the medicament delivery device further comprises a blocking element configured to obstruct rotational movement of the lock ring about the longitudinal axis relative to the body; wherein the blocking element is arrangeable in a first position in which the lock ring is in the first state, and a second position in which the lock ring is in the second state; wherein the medicament delivery device is configured such that moving the cap along the distal direction causes the blocking element to move from the first position to the second position.

7. The medicament delivery device of claim 6 , wherein the medicament delivery device is configured such that moving the blocking element from the first position to the second position comprises moving the blocking element along the longitudinal axis relative to the body in the distal direction.

8. The medicament delivery device of claim 6 , wherein the body is an outer body and the medicament delivery device further comprises an inner body comprising the blocking element and arranged inside the outer body and moveable relative thereto along the longitudinal axis; wherein the inner body is removably couplable to the cap such that when the cap is in the capped position the inner body is coupled to the cap such that movement of the cap in the distal direction causes the inner body to move relative to the outer body along the distal direction together with the cap.

9. The medicament delivery device of claim 8 , wherein the medicament delivery device is configured such that during movement of the cap in the distal direction along a first axial range of motion the inner body is coupled to the cap and the blocking element is caused to move from the first position into the second position, and completion of the movement of the cap along the first axial range of motion causes the cap to become decoupled from the inner body, such that the inner body is decoupled from the cap during movement of the cap in the distal direction along a subsequent second axial range of motion.

10. The medicament delivery device of claim 9 , wherein the cap comprises one or more arms extending generally parallel to the longitudinal axis and each comprising a clip configured to form a snap fit with the inner body to couple the inner body to the cap; wherein the medicament delivery device is configured such that completion of the movement of the cap along the first axial range of motion causes the one or more arms to deflect or flex relative to the inner body to decouple the cap from the inner body.

11. The medicament delivery device of claim 8 , wherein the medicament delivery device further comprises one or more stoppers configured to limit an axial range of motion of the inner body relative to the outer body along the longitudinal axis.

12. The medicament delivery device of claim 8 , wherein the medicament delivery device further comprises:

a plunger removably couplable to the inner body and configured to place the needle in an injection position for injecting medicament, wherein moving the actuation member relative to the outer body along the longitudinal axis to actuate the medicament delivery device causes the plunger to become decoupled from the inner body and to move along the distal direction; and

a second biasing member configured to bias the plunger towards the distal end of the body, wherein the second biasing member is arranged inside the inner body.

13. The medicament delivery device of claim 12 , wherein the plunger comprises one or more deflectable arms each comprising a clip configured to be received in an aperture of the inner body to couple the plunger to the inner body, and wherein the medicament delivery device is configured such that moving the actuation member in the distal direction causes each of the one or more deflectable arms to deflect relative to the longitudinal axis to cause the clip to be moved out from the aperture to permit the plunger to move relative to the inner body along the distal direction.

14. The medicament delivery device of claim 6 , wherein the blocking element comprises a radially protruding element configured to be received in a receiving segment of the lock ring when the blocking element is in the second position, to permit the lock ring to rotate relative to the blocking element about the longitudinal axis.

15. The medicament delivery device of claim 6 , wherein the lock ring comprises a first annular portion and a second annular portion arranged along the longitudinal axis; wherein the first annular portion comprises a first receiving segment configured to receive the blocking element and which extends around a first portion of the circumference of the lock ring; wherein the second annular portion comprises a second receiving segment configured to receive the blocking element and which extends around a second portion of the circumference of the lock ring; wherein each of the first and second receiving segments comprises an aperture, recess, channel, groove or cut-out; and wherein the second portion is larger than the first portion, such that when the blocking element is received in the first receiving segment the blocking element is in the first position and when the blocking element is received in the second receiving segment the blocking element is in the second position.

16. The medicament delivery device of claim 6 , wherein the medicament delivery device is configured such that movement of the blocking element along the longitudinal axis causes the lock ring to rotate about the longitudinal axis.

17. The medicament delivery device of claim 6 , wherein the lock ring comprises an inclined surface that is angled relative to a circumferential direction of the lock ring which circumscribes the longitudinal axis, wherein the blocking element is configured to engage with the inclined surface, such that movement of the blocking element along the longitudinal axis causes the inclined surface to move relative to the blocking element to cause the lock ring to rotate about the longitudinal axis.

18. The medicament delivery device of claim 6 , wherein the lock ring comprises a receiving element comprising a slot, a groove, a channel, an aperture or a cut-out configured to receive the blocking element; wherein the receiving element comprises a first portion extending generally parallel to the longitudinal axis, and a second portion extending generally along a circumferential direction which circumscribes the longitudinal axis and/or extending at an angle relative to said circumferential direction.

19. The medicament delivery device of claim 1 , wherein the medicament delivery device is configured such that moving the cap in the distal direction away from the capped position causes the lock ring to rotate from the first position towards the second position.

20. The medicament delivery device of claim 1 , wherein the medicament delivery device contains a medicament.

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