Peritoneal dialysis cassette
An example article includes a rigid member defining a plurality of fluid flow paths and a plurality of flexible tubes each defining a lumen and configured to be occluded via a pressure applied externally to the lumen and unoccluded in an absence of the externally applied pressure. Each flexible tube of the plurality of flexible tubes is configured to be fluidically connected to a flow path of the plurality of flow paths, and different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.
1 . An article comprising:
a rigid member defining a plurality of fluid flow paths; and
a plurality of flexible tubes within the rigid member, each of the plurality of flexible tubes defining a lumen and configured to be occluded via a pressure applied externally to at least a portion of the lumen of a respective flexible tube of the plurality of flexible tubes within the rigid member and unoccluded in an absence of the externally applied pressure,
wherein each flexible tube of the plurality of flexible tubes is configured to be fluidically connected within the rigid member to a fluid flow path of the plurality of fluid flow paths,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes.
2 . The article of claim 1 , wherein each flexible tube of the plurality of flexible tubes is configured to be occluded via at least one of a mechanical actuator, a pneumatic actuator, or a mechanical and pneumatic actuator configured to collapse the lumen.
3 . The article of claim 1 , wherein the externally applied pressure is greater than or equal to 10 newtons (N) and less than or equal to 15N.
4 . The article of claim 1 , further comprising at least one of a temperature sensor or a pressure sensor configured to sense a temperature or a pressure, respectively, of fluid in at least one fluid flow path of the plurality of fluid flow paths.
5 . The article of claim 1 , wherein the rigid member comprises a first rigid member and a second rigid member connected together, each of the first rigid member and the second rigid member defining a plurality of channels that form the plurality of fluid flow paths when the first rigid member and the second rigid member are connected together.
6 . The article of claim 5 , wherein the first rigid member and the second rigid member are connected together via at least one of laser welding, ultrasonic welding, or hot plate welding.
7 . The article of claim 1 , wherein the rigid member further defines a plurality of fluidic connectors, each fluidic connector of the plurality of fluidic connectors being fluidically connected to a fluid flow path of the plurality of fluid flow paths, wherein each flexible tube of the plurality of flexible tubes is configured to be connected to a respective fluidic connector of the plurality of fluidic connectors by at least one of a friction fit or a heat seal.
8 . The article of claim 1 , wherein the plurality of fluid flow paths is less than or equal to ten fluid flow paths configured to selectively interconnect a plurality of external fluid connections, the plurality of external fluid connections comprising at least one patient fluid connection, at least one dialysate fluid connection, at least one drain fluid connection, and at least one fluid heating fluid connection.
9 . A system comprising:
a cassette comprising:
a rigid member defining a plurality of fluid flow paths, each of the plurality of fluid flow paths including at least one fluidic connection to a fluid input or a fluid output of the rigid member; and
a plurality of flexible tubes within the rigid member, each of the plurality of flexible tubes defining a lumen and configured to be occluded via a pressure applied externally to at least a portion of the lumen of a respective flexible tube of the plurality of flexible tubes within the rigid member and unoccluded in an absence of the externally applied pressure,
wherein each flexible tube of the plurality of flexible tubes is configured to be fluidically connected to a fluid flow path of the plurality of fluid flow paths,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes;
a peritoneal dialysis device comprising a plurality of actuators configured to apply the pressure externally to the plurality of flexible tubes; and
control circuitry configured to selectively cause one or more actuators of the plurality of actuators to apply the pressure to or release the pressure from one or more flexible tubes of the plurality of flexible tubes.
10 . The system of claim 9 , further comprising:
a compressor configured to provide air to the plurality of actuators; and
a pneumatic pump configured to move fluid through the plurality of fluid flow paths,
wherein the plurality of actuators are pneumatic actuators, wherein the compressor is configured to provide less than 3,000,000 Pascals (Pa) of pressure to the pneumatic actuators and the pneumatic pump.
11 . The system of claim 9 , wherein the plurality of actuators comprises at least one of a mechanical actuator, a pneumatic actuator, or a mechanical and pneumatic actuator.
12 . The system of claim 9 , wherein the cassette further comprises at least one of a temperature sensor or a pressure sensor configured to sense a temperature or a pressure, respectively, of fluid in at least one fluid flow path of the plurality of fluid flow paths.
13 . The system of claim 9 , wherein the rigid member comprises a first rigid member and a second rigid member connected together, each of the first rigid member and the second rigid member defining a plurality of channels that form the plurality of fluid flow paths when the first rigid member and the second rigid member are connected together.
14 . The system of claim 13 , wherein the first rigid member and the second rigid member are connected together via at least one of laser welding, ultrasonic welding, or hot plate welding.
15 . The system of claim 9 , wherein the rigid member further includes a first connector and a second connector configured to fluidically connect respective flexible tubes of the plurality of flexible tubes to the rigid member, wherein the respective flexible tubes are configured to mechanically connect to the first connector and the second connector by at least one of a friction fit or a heat seal.
16 . The system of claim 9 , wherein the plurality of fluid flow paths is less than or equal to ten fluid flow paths configured to selectively interconnect a plurality of external fluid connections, the plurality of external fluid connections comprising at least one patient fluid connection, at least one dialysate fluid connection, at least one drain fluid connection, and at least one fluid heating fluid connection.
17 . The system of claim 9 , wherein the control circuitry is configured to select and form one fluid flow path of the plurality of fluid flow paths via causing a first set of actuators of the plurality of actuators to occlude a corresponding first set of flexible tubes of the plurality of flexible tubes and causing a second set of actuators of the plurality of actuators to unocclude a second set of flexible tubes of the plurality of flexible tubes, wherein the first set of actuators and the first set of flexible tubes are different from the second set of actuators and the second set of flexible tubes.
18 . A method comprising:
selecting, via control circuitry, a fluid flow path of a plurality of fluid flow paths defined by a peritoneal dialysis cassette, the peritoneal dialysis cassette comprising:
a rigid member defining the plurality of fluid flow paths, each fluid flow path of the plurality of fluid flow paths including at least one fluidic connection to a fluid input or a fluid output of the rigid member; and
a plurality of flexible tubes within the rigid member, each of the plurality of flexible tubes defining a lumen and configured to be occluded via a pressure applied externally to at least a portion of the lumen of a respective flexible tube of the plurality of flexible tubes and unoccluded in an absence of the externally applied pressure,
wherein each flexible tube of the plurality of flexible tubes is configured to be fluidically connected to a fluid flow path of the plurality of fluid flow paths of the rigid member,
wherein different fluid flow paths of the plurality of fluid flow paths are defined by occluding different flexible tubes of the plurality of flexible tubes; and
causing, via the control circuitry, one or more actuators to occlude at least one flexible tube of the plurality of flexible tubes to define the fluid flow path.
19 . The method of claim 18 , wherein the one or more actuators is a first set of actuators and the at least one flexible tube comprises a first flexible tube, the method further comprising causing, via the control circuitry, at least one second actuator of the one or more actuators to unocclude a second flexible tube of the plurality of flexible tubes to define the fluid flow path.
20 . The method of claim 19 , wherein the fluid flow path is a first fluid flow path, the method further comprising:
selecting, via the control circuitry, a second fluid flow path of the plurality of fluid flow paths different from the first fluid flow path; and
forming the second fluid flow path by at least:
causing, via the control circuitry, the at least one second actuator to occlude the second flexible tube; and
causing, via the control circuitry, an actuator of the one or more actuators different from the second actuator to unocclude a flexible tube of the plurality of flexible tubes different from the second flexible tube.