IP Library Granted Patent US 12,629,342
Granted Patent B1
US 12,629,342 · App. 18/125,366 · Granted May 19, 2026

Systems, methods, and apparatuses for delivery of active compounds

Inventors: Jordan Schindler (Charlotte, NC); Michael Drzewinski (Denver, NC)
Assignee: Textile-Based Delivery, Inc.
A61K9/70D03D15/283G16H10/60G16H40/67D10B2401/04D10B2401/16D10B2401/18D10B2501/00
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Quick Facts
Patent No.
US 12,629,342
App. No.
18/125,366
Granted
May 19, 2026
Kind
B1
Abstract

Drug delivery systems and wearable articles including the drug delivery systems are provided. The drug delivery systems include yarns, yarn precursors, threads, filaments, and/or fibers coated with at least one polymer and at least one active compound. The drug delivery systems include at least one conductive and/or electromagnetic yarn, yarn precursor, thread, filament, and/or fiber. The drug delivery systems further include biometric data, environmental data, and at least one remote device. Parameters of the wearable articles are operable to be adjusted based on the biometric data and/or the environmental data.

Claims (51)

1 . An article for delivery of an active compound to the skin of a user comprising:

a textile including at least one printed circuit board (PCB), wherein the at least one PCB includes a processor, a heater, a memory, and a battery;

wherein the textile comprises at least one electromagnetic fiber and at least one loaded fiber, wherein the loaded fiber comprises a polymeric matrix including at least one active compound;

wherein a heater is disposed on or integrated with the at least one PCB and is operable to generate a voltage,

wherein the voltage is electrically transmitted from the at least one PCB to the at least one electromagnetic fiber;

wherein the voltage is conducted by the at least one electromagnetic fiber;

wherein increasing the voltage increases the temperature of the loaded fiber, wherein increasing the temperature of the loaded fiber increases the rate of release of the at least one active compound; and

wherein decreasing the voltage decreases the temperature of the loaded fiber, wherein decreasing the temperature of the loaded fiber decreases the rate of release of the at least one active compound.

2 . The article of claim 1 , wherein the textile further comprises at least one sensor, wherein the at least one sensor detects physiological data relating to the physiological condition of a user and/or environmental data relating to the environment of the user.

3 . The article of claim 2 , wherein the at least one PCB is operable to analyze the physiological data and/or the environmental data detected by the at least one sensor and increase and/or decrease the voltage based on analysis of the data.

4 . The article of claim 1 , further comprising;

a user device and a remote server including a database;

wherein the user device is in network communication with the at least one PCB and the remote server;

wherein the database is operable to store at least one user profile associated with the user device; and

wherein the user device receives an input via a graphic user interface (GUI) and analyzes the input using an analytics engine, wherein the user device is operable to transmit a signal to the at least one PCB to increase and/or decrease the voltage based on the analysis of the input.

5 . The article of claim 4 , wherein the user device is operable to receive activity data and store the activity data on the database of the remote server, wherein the activity data includes at least one activity, a start time of the at least one activity, and an end time of the at least one activity.

6 . The article of claim 1 , wherein the at least one PCB is operable to increase and/or decrease the voltage in time-based intervals.

7 . The article of claim 1 , wherein the at least one electromagnetic fiber is a fiber coated with at least one layer of electrically conductive ink and/or formed from at least one electromagnetic material selected from a group consisting of stainless steel, copper, aluminum, gold, silver, tungsten, iron, titanium, chromium, platinum, palladium, and nickel.

8 . The article of claim 1 , wherein the textile is incorporated into a wearable garment, bedding, toweling, an orthopedic cast, a wound dressing, a bandage, a skin guard, a wrist band, an arm band, a knee pad, an athletic supporter, a robe, a neck band, a head band, a pair of gloves, a diaper, or a joint brace.

9 . A system for automatic delivery of an active compound to the skin of a user comprising:

a textile, at least one user device, and at least one server including at least one database;

wherein the at least one server is in network communication with the at least one user device;

wherein the at least one user device includes a graphical user interface (GUI) and an analytics engine;

wherein the at least one database stores at least one user profile and at least one set of parameters for data correlating to the at least one user profile associated with the at least one user device;

wherein the textile comprises a printed circuit board (PCB) and at least one sensor, wherein the at least one sensor collects physiological data and/or environmental data relating to a physiological condition and/or an environmental condition associated with the at least one user profile;

wherein the at least one sensor is operable to transmit the physiological data and/or the environmental data to the at least one user device;

wherein the analytics engine is operable to analyze the transmitted physiological data and/or the transmitted environmental data in view of the at least one user profile to determine that the physiological data and/or the environmental data does not meet the at least one set of parameters;

wherein the textile further comprises at least one electromagnetic fiber and at least one loaded fiber, wherein the at least one loaded fiber comprises a polymeric matrix including an active compound;

wherein a processor of the at least one PCB receives a signal from the at least one user device, wherein a heater generates a voltage in response to the received signal, wherein the voltage is electrically transmitted from the at least one PCB to the at least one electromagnetic fiber, wherein the voltage is conducted by the at least one electromagnetic fiber;

wherein increasing the voltage increases the temperature of the loaded fiber, wherein increasing the temperature of the loaded fiber increases the rate of release of the at least one active compound; and

wherein decreasing the voltage decreases the temperature of the loaded fiber, wherein decreasing the temperature of the loaded fiber decreases the rate of release of the at least one active compound.

10 . The system of claim 9 , wherein upon determination that the physiological data and/or the environmental data collected by the sensor does not fall within at least one input parameter, the at least one PCB is operable to increase and/or decrease the voltage.

11 . The system of claim 9 , wherein the at least one PCB is operable to determine a baseline for the physiological data and/or the environmental data, wherein upon determination that the physiological data and/or the environmental data exceeds an objective parameter related to the baseline the PCB is operable to increase and/or decrease the voltage.

12 . The system of claim 9 , wherein the at least one PCB of at least two textiles are operable to be connected to a single user device.

13 . The system of claim 9 , wherein the at least one user device is operable to connect to a global positioning system (GPS), wherein the at least one PCB is operable to increase the voltage based on a location of the at least one user device.

14 . The system of claim 9 , wherein the at least one database is operable to store medical information associated with the at least one user profile.

15 . The system of claim 9 , wherein the user device is operable to receive activity data and store the activity data on the database of the remote server, wherein the activity data includes at least one activity, a start time of the at least one activity, and an end time of the at least one activity.

16 . The system of claim 9 , wherein the textile is incorporated into a wearable garment, bedding, toweling, an orthopedic cast, a wound dressing, a bandage, a skin guard, a wrist band, an arm band, a knee pad, an athletic supporter, a robe, a neck band, a head band, a pair of gloves, a diaper, or a joint brace.

17 . A system for automatic delivery of an active compound to the skin of a user comprising:

a textile including at least one printed circuit board (PCB) and a heater, wherein the at least one PCB comprises a processor, a memory, and a battery, wherein the heater is disposed on or integrated with the at least one PCB; and

at least one user device and at least one server including at least one database;

wherein the at least one server is in network communication with the at least one user device;

wherein the at least one server stores at least one user profile associated with the at least one user device, wherein the at least one user profile comprises medical history, biometric history, environmental data history, and system preferences;

wherein the at least one user device includes a graphical user interface (GUI) configured to receive and display biometric data, and to allow adjustment of delivery parameters by a user;

wherein the at least one user device is in network communication with the at least one PCB;

wherein the textile comprises at least one electromagnetic fiber and at least one loaded fiber, wherein the at least one loaded fiber comprises an active compound dispersed within a polymeric matrix;

wherein the at least one PCB receives a signal from the at least one user device to trigger the release of the active compound from the at least one loaded fiber; and

wherein the at least one PCB transmits the signal to the heater, wherein the heater applies a voltage to the at least one electromagnetic fiber.

18 . The system of claim 17 , wherein the at least one user device is operable to connect to a global positioning system (GPS), wherein the at least one PCB is operable to increase the voltage based on a location of the at least one user device.

19 . The system of claim 17 , wherein the at least one user device receives an input via a graphic user interface (GUI) and analyzes the input using an analytics engine, wherein the user device is operable to transmit a signal to the at least one PCB to increase and/or decrease the applied voltage based on an analysis of the input from the analytics engine.

20 . The system of claim 17 , wherein the at least one PCB of at least two textiles are operable to connect to a single user device.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 23, 2023
From: SCHINDLER, JORDAN; DRZEWINSKI, MICHAEL
To: TEXTILE-BASED DELIVERY, INC.
Reel/Frame 063080/0460 →
Continuity (1)
Provisional Application 63323288 · Mar 24, 2022
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