IP Library Granted Patent US 12,694,641
Granted Patent B2
US 12,694,641 · App. 18/010,387 · Granted Jul 28, 2026

Analysis system and production method of analysis image

Inventor: Hideo Utsumi (Shizuoka, JP)
Assignee: ReMI Corporation
G06V10/60
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Quick Facts
Patent No.
US 12,694,641
App. No.
18/010,387
Granted
Jul 28, 2026
Kind
B2
Abstract

An analysis system in which an image component part is provided, and the image component part includes a memory part and an image operation part, the memory part stores at least core image pixel information and operating image pixel information, the core image pixel information and the operating image pixel information include the same sample and the same analysis target region and include a predetermined number of pixels imaged by different imaging systems, the operating image pixel information includes analysis information and is image pixel information with luminance and/or resolution lower than the core image pixel information, and the image operation part performs operations including Hadamard product for at least one or more pieces of the core image pixel information and at least one or more pieces of the operating image pixel information so as to build a new created image pixel information.

Claims (24)

1 . An analysis system, comprising:

an image component part, wherein the image component part includes a memory part and an image operation part;

the memory part stores at least core image pixel information and operating image pixel information;

the core image pixel information and the operating image pixel information include the same sample containing analysis target and the same analysis target region and include a predetermined number of pixels imaged by different imaging systems;

the operating image pixel information includes analysis information associated with a property parameter to be quantitatively detected in the same analysis target region;

the operating image pixel information is generated by reducing a number of pixels to one fourth or less with compared to the core image pixel information thereby increasing a signal-to-noise ratio;

the core image pixel information does not include the analysis information, or does include the analysis information but is not associated with the property parameter to be quantitatively detected, such that the core image pixel information contains a profile of the analysis target with higher sharpness than the profile of the analysis target contained in the operating image pixel information;

the image operation part:

executes positioning of the same analysis target region between the core image pixel information and the operating image pixel information, matches pixel numbers in the same analysis target region between the core image pixel information and the operating image pixel information; and

builds new created image pixel information by performing operations including Hadamard product, thereby fusing at least one or more pieces of the core image pixel information and at least one or more pieces of the operating image pixel information to increase contrast, which is defined as difference in the property parameter between the analysis target region and surrounding regions in the new created image pixel information.

2 . The analysis system according to claim 1 , further comprising:

an imaging part.

3 . A non-transitory computer-readable recording medium which stores a program to operate the analysis system according to claim 1 .

4 . The analysis system according to claim 1 , wherein the property comprises concentration of Cmp (3-carbamoyl-PROXYL), dynamic nuclear polarization (DNP), relaxation speed, diffusion, perfusion, magnetic susceptibility, or chemical shift.

5 . The analysis system according to claim 1 , wherein the operating image pixel information is generated by reducing the number of pixels to one sixty-fourth or less with compared to the core image pixel information thereby increasing the signal-to-noise ratio.

6 . A production method of an analysis image for building a new created image, comprising:

preparing core image pixel information and operating image pixel information;

preparing:

the operating image pixel information including analysis information associated with a property parameter to be quantitatively detected in an analysis target region, wherein the operating image pixel information is generated by reducing a number of pixels to one fourth or less with compared to the core image pixel information thereby increasing a signal-to-noise ratio;

the core image pixel information not including the analysis information, or including the analysis information that is not associated with the property parameter to be quantitatively detected in the same analysis target region as the one in the core image pixel information, and the operating image pixel information and the core image pixel information being image pixel information including the same sample containing the same analysis target in the target region and the same analysis target region, respectively, and including a predetermined number of pixels imaged by imaging systems different from each other;

executing positioning of the same analysis target region between the core image pixel information and the operating image pixel information, and matches pixel numbers in the same analysis target region between the core image pixel information and the operating image pixel information;

and building new created image pixel information by performing operations including Hadamard product, thereby fusing at least one or more pieces of the core image pixel information and at least one or more pieces of the operating image pixel information to increase contrast, which is defined as difference in the property parameter between the analysis target region and surrounding regions in the new created image pixel information.

7 . The production method according to claim 6 , wherein the property comprises concentration of Cmp (3-carbamoyl-PROXYL), dynamic nuclear polarization (DNP), relaxation speed, diffusion, perfusion, magnetic susceptibility, or chemical shift.

8 . The production method according to claim 6 , wherein the operating image pixel information is generated by reducing the number of pixels to one sixty-fourth or less with compared to the core image pixel information thereby increasing the signal-to-noise ratio.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 14, 2022
From: UTSUMI, HIDEO
To: REMI CORPORATION
Reel/Frame 062093/0041 →
Priority Claims (1)
JP 2021-167393 · Oct 12, 2021 · national
Continuity (1)
Related Publication 20240290067A1 · Aug 29, 2024
References Cited (35)
US 4891593A · Lurie et al. · 1990 [cited by applicant]
US 10835199B2 · Chtcheprov · 2020 [cited by examiner]
US 20120293171A1 · Dannels et al. · 2012 [cited by applicant]
US 20130012805A1 · Penn · 2013 [cited by examiner]
US 20160018501A1 · Kimura · 2016 [cited by applicant]
US 20170103529A1 · Shi · 2017 [cited by examiner]
US 20170160365A1 · Helle et al. · 2017 [cited by applicant]
US 20170234952A1 · Zhang · 2017 [cited by examiner]
US 20180005415A1 · Wang · 2018 [cited by examiner]
US 20180095153A1 · Kimura · 2018 [cited by examiner]
US 20180153502A1 · Duric · 2018 [cited by examiner]
US 20180260649A1 · Kadambe · 2018 [cited by examiner]
US 20200357153A1 · Zhao · 2020 [cited by examiner]
US 20220301112A1 · DeLaRosa · 2022 [cited by examiner]
CN 105072991A · 2015 [cited by applicant]
CN 106415298A · 2017 [cited by applicant]
JP 2010046103A · 2010 [cited by applicant]
WO 9204640A1 · 1992 [cited by applicant]
WO 9403824A1 · 1994 [cited by applicant]
WO WO2015152957A1 · 2015 [cited by examiner]
International Search Report issued in PCT/JP2022/025081 mailed on Sep. 13, 2022 with English Translation (4 pages). [cited by applicant]
Written Opinion of the International Searching Authority issued in PCT/JP2022/025081 mailed on Sep. 13, 2022 with English Translation (8 pages). [cited by applicant]
W. Youngdee et al, Optimization of field-cycled PEDRI for in vivo imaging of free radicals, Phys, Med. Biol. 46 (2001) 2531-2544 (14 pages). [cited by applicant]
D. Lurei et al. Field-cycled PEDRI imaging of free radicals with detection at 450mT, Magn. Reson. Imaging 23,175-181 (2005) (7 pages). [cited by applicant]
George P.H. Styan, Hadamard Products and Multivariate Statistical Analysis, Linear Algebra and Its Application 6: 217-240 (1973) (24 pages). [cited by applicant]
Deshmukh, Manjusha, et al., Image Fusion and Image Quality Assessment of Fused Images, International Journal of Image processing, 2010, vol. 4, Issue—5, pp. 484-508 2. Fusion Algorithms-3. Fused Image Evaluation (25 pag… [cited by applicant]
Volker, Christoph, et al., Multi sensor data fusion approach for automatic honeycomb detection in concrete, NDT & E International, 2015, vol. 71, pp. 54-60 1 Introduction-4 Evaluation of Fusion Results (22 pages). [cited by applicant]
Notice of Reasons for Rejection dated Mar. 7, 2023 issued in Japanese Patent Application No. 2022-579777 with English Translation (9 pages). [cited by applicant]
Extended European Search Report issued in European Patent Application No. 22817518.8, dated on May 27, 2024 (12 pages). [cited by applicant]
Katherine Rose Fisher, Devising New Biomedical Imaging Applications for Metallodrugs based on an Improved Understanding of their Electronic and Magnetic Properties, PHD Thesis—Linacre College—University of Oxford, Oct. … [cited by applicant]
“MRIQUESTIONS.com” published by Allen D. Elster, MD FACR (2015), on the website at https://www.mriquestions.com/index.html (2 pages). [cited by applicant]
“DWI b-Value” in “Question and Ansewres in MRI” published by Allen D. Elster, MD FACR (2015), on the website at https://www.mriquestions.com/what-is-the-b-value.html (2 pages). [cited by applicant]
“Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient” (J. Chem. Phys. 42, 288 (1965); doi: 10.1063/1.1695690), publiched Jan. 1, 1965, Authers: E. 0. Stejskal and J. E. Tanner (6 … [cited by applicant]
Office Action issued in Chinese Patent Application No. 202280005417.X dated Feb. 15, 2026, with English Translation (10 pages). [cited by applicant]
Communication pursuant to Article 94(3) issued in European Patent Application No. 22817518.8, dated on Apr. 20, 2026, with English Translation (7 pages). [cited by applicant]