IP Library › Granted Patent US 7,194,313
Granted Patent B2
US 7,194,313 · App. 10/864,070 · Granted Mar 20, 2007

Baroreflex therapy for disordered breathing

Assignee: Cardiac Pacemakers, Inc.
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 7,194,313
App. No.
10/864,070
Granted
Mar 20, 2007
Kind
B2
Abstract

A baroreflex stimulator is described that treats disordered breathing in a patient. The stimulator includes a pulse generator to provide a baroreflex stimulation signal through an electrode, and a modulator to modulate the baroreflex stimulation signal based on a circadian rhythm template.

Claims (43)

1. A disordered breathing therapy system, comprising:

one or more electrodes configured to deliver an electrical stimulation signal to a region associated with a patient's baroreflex response;

a template generator coupled to the pulse generator, the template generator configured to generate a circadian rhythm template and

a pulse generator coupled to the one or more electrodes, the pulse generator configured to control delivery of an electrical stimulation therapy using the one or more electrodes and the circadian rhythm template, the electrical stimulation therapy modifying a patient's baroreflex response to treat disordered breathing.

2. The system of claim 1 , wherein the pulse generator is configured to treat apnea.

3. The system of claim 1 , wherein the pulse generator is configured to modulate the electrical stimulation therapy using the circadian rhythm template.

4. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on a cardiovascular parameter.

5. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on arterial pressure.

6. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on heart rate.

7. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on stroke volume.

8. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on cardiac output.

9. The system of claim 1 , wherein the template generator is configured to generate the circadian rhythm template based on total peripheral resistance.

10. The system of claim 1 , wherein the pulse generator is configured to modulate one or more parameters of the electrical stimulation therapy modifying a patient's baroreflex response to treat disordered breathing.

11. The system of claim 10 , wherein the one or more parameters comprise a stimulation frequency.

12. The system of claim 10 , wherein the one or more parameters comprise a stimulation amplitude.

13. The system of claim 10 , wherein the one or more parameters comprise a stimulation burst frequency.

14. The system of claim 1 , wherein the pulse generator is configured to modulate the electrical stimulation therapy modifying the patient's baroreflex response to mimic a circadian rhythm.

15. A system for treating disordered breathing in a patient, comprising:

means for delivering electrical stimulation to one or more regions associated with a patient's baroreflex response;

means for generating a circadian rhythm template; and

means for controlling delivery of the electrical stimulation based on the circadian rhythm template to modify a patient's baroreflex response to treat the disordered breathing.

16. The system of claim 15 , further comprising means for modulating the electrical stimulation therapy to mimic a circadian rhythm.

17. The system of claim 15 , further comprising means for generating a circadian rhythm template and means for modulating the electrical stimulation therapy using the circadian rhythm template.

18. The system of claim 15 , further comprising means for modulating one or more parameters of the electrical stimulation.

19. A method for treating disordered breathing in a patient, comprising:

generating a circadian rhythm template; and

delivering electrical stimulation therapy that modifies a patient's baroreflex response to treat the disordered breathing based on the circadian rhythm template.

20. The method of claim 19 , wherein delivering the electrical stimulation therapy modifying the patient's baroreflex response comprises delivering the electrical stimulation therapy to treat apnea.

21. The method of claim 19 , wherein delivering the electrical stimulation therapy modifying the patient's baroreflex response comprises electrically stimulating one or more baroreceptor sites.

22. The method of claim 19 , wherein delivering the electrical stimulation therapy modifying the patient's baroreflex response comprises delivering the electrical stimulation therapy modifying the patient's baroreflex response based on circadian rhythm.

23. The method of claim 19 , wherein delivering the electrical stimulation therapy modifying the patient's baroreflex response comprises:

modulating the electrical stimulation based on the circadian rhythm template.

24. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on a cardiovascular parameter.

25. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on arterial pressure.

26. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on heart rate.

27. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on stroke volume.

28. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on cardiac output.

29. The method of claim 19 , wherein generating the circadian rhythm template comprises generating the circadian rhythm template based on total peripheral resistance.

30. The method of claim 19 , wherein delivering electrical stimulation therapy modifying the patient's baroreflex response comprises modulating a parameter of the electrical stimulation therapy.

31. The method of claim 30 , wherein modulating the parameter of the electrical stimulation therapy comprises modulating electrical stimulation frequency.

32. The method of claim 30 , wherein modulating the parameter of the electrical stimulation therapy comprises modulating electrical stimulation amplitude.

33. The method of claim 30 , wherein modulating the parameter of the electrical stimulation therapy comprises modulating electrical stimulation burst frequency.

34. The method of claim 19 , wherein delivering the electrical stimulation therapy modifying the patient's baroreflex response comprises delivering the electrical stimulation modifying the patient's baroreflex response to mimic a natural circadian rhythm.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 1, 2004
From: LIBBUS, IMAD
To: CARDIAC PACEMAKERS, INC.
Reel/Frame 015324/0389 →
Continuity (2)
Division 1074684400 · Dec 24, 2003
Related Publication 20050143785A1 · Jun 30, 2005