IP Library Granted Patent US 7,346,521
Granted Patent B2
US 7,346,521 · App. 09/941,496 · Granted Mar 18, 2008

System and methods for generating physician profiles concerning prescription therapy practices

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Quick Facts
Patent No.
US 7,346,521
App. No.
09/941,496
Granted
Mar 18, 2008
Kind
B2
Abstract

A system and methods for generating a profile concerning the prescription therapy practices of physicians in a therapeutic area of interest. A plurality of historical de-identified patient prescription records are analyzed, and the records are categorized based on changes in the dosage or the prescription product between prescriptions for a particular de-identified patient. The prescriptions may be categorized based on the duration between the due date of a prescription and the date the prescription was filled. This information may be summarized for each physician for each product in the therapy area of interest.

Claims (53)

1. A method for generating a profile concerning prescription therapy practices of at least one physician in a therapeutic area of interest, comprising the steps of:

(a) receiving a plurality of historical de-identified patient prescription records corresponding to prescriptions issued to at least one de-identified patient by at least one physician, each record including de-identified patient identification number, dosage, and prescription product information;

(b) receiving user-specified information defining a subset of the historical de-identified patient prescription records;

(c) extracting at least one relevant historical de-identified patient prescription record from the received historical de-identified patient prescription records based on the subset;

(d) for each de-identified patient, comparing dosage and prescription product information contained in a first extracted historical de-identified patient record with dosage and prescription product information contained in a second extracted historical de-identified patient record; and

(e) for each comparison made in step (d), categorizing a prescription based on a change in dosage or prescription product.

2. The method of claim 1 , wherein the step of receiving user-specified information further comprises receiving information concerning an observation period.

3. The method of claim 1 , wherein the step of extracting de-identified patient prescription records further comprises discarding a historical de-identified patient prescription record having an eligibility of shorter duration than the observation period.

4. The method of claim 1 , wherein the step of categorizing prescriptions further comprises categorizing a prescription of a product as a new therapy start when a de-identified patient has had no other prescriptions in a therapeutic area to which the product pertains.

5. The method of claim 1 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a therapy switch when a de-identified patient has had no other prescriptions of the product, and when the de-identified patient has had a prescription of a second product within a therapeutic area to which the product pertains that was not prescribed on the same day as the prescription.

6. The method of claim 1 , wherein step of categorizing prescriptions further comprises categorizing a prescription as an add-on therapy when the de-identified patient had no other prescriptions for the product but had a prescription for a second product within the therapeutic area to which the product pertains that was prescribed on the same day.

7. The method of claim 1 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a titration decrease when a de-identified patient has previously had a prescription for the product at a higher dosage.

8. The method of claim 1 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a titration increase when a de-identified patient has previously had a prescription for the product at a lower dosage.

9. The method of claim 1 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as continued therapy when a de-identified patient has previously had a prescription for the product at the same dosage.

10. A method for generating a profile concerning prescription therapy practices of at least one physician in a therapeutic area of interest comprising the steps of:

(a) receiving a plurality of historical de-identified patient prescription records corresponding to prescriptions issued to at least one de-identified patient by at least one physician, each record including de-identified patient identification number, prescription product information, date dispensed, dosage, number of days supplied, and refill information;

(b) receiving user-specified information defining a subset of the historical de-identified patient prescription records;

(c) extracting at least one relevant historical de-identified patient prescription record from the received historical de-identified patient prescription records based on the subset;

(d) for each de-identified patient, comparing dosage and prescription product information contained in a first extracted historical de-identified patient record with dosage and prescription product information contained in a second extracted historical de-identified patient record;

(e) for each comparison made in step (d), categorizing a prescription based on a change in dosage or prescription product;

(f) extracting at least one relevant historical de-identified patient prescription record from the prescriptions categorized at step (e) based on the refill information;

(g) for each de-identified patient, determining a refill due date based on the dosage and the number of days supplied for a first prescription;

(h) for each de-identified patient, comparing the refill due date of the first prescription with the date dispensed for a second prescription; and

(i) for each comparison made in step (h), categorizing the de-identified patient based on the duration between the refill due date of the first prescription and the date dispensed for the second prescription.

11. The method of claim 10 , wherein the step of receiving user-specified information further comprises receiving information concerning an observation period.

12. The method of claim 11 , further comprising a step of discarding, after step (e), a historical de-identified patient prescription record for a de-identified patient having more than one physician during the observation period.

13. The method of claim 11 , wherein the step of extracting de-identified patient prescription records based on refill information further comprises discarding a historical de-identified patient prescription record not having a refill due within the observation period.

14. The method of claim 10 , wherein the step of categorizing prescriptions further comprises categorizing a prescription of a product as a new therapy start when a de-identified patient has had no other prescriptions in a therapeutic area to which the product pertains.

15. The method of claim 10 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a therapy switch when a de-identified patient has had no other prescriptions of the product, and when the de-identified patient has had a prescription of a second product within a therapeutic area to which the product pertains that was not prescribed on the same day as the prescription.

16. The method of claim 15 , further comprising a step of discarding, after step (e), a historical de-identified patient prescription record for a prescription categorized as a therapy switch.

17. The method of claim 10 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a titration decrease when a de-identified patient has previously had a prescription for the product at a higher dosage.

18. The method of claim 17 , further comprising a step of discarding, after step (e), a historical de-identified patient prescription record for a prescription categorized as a titration decrease.

19. The method of claim 10 , wherein the step of categorizing prescriptions further comprises categorizing a prescription as a titration increase when a de-identified patient has previously had a prescription for the product at a lower dosage.

20. The method of claim 19 , further comprising a step of discarding, after step (e), a historical de-identified patient prescription record for a prescription categorized as a titration increase.

21. The method of claim 10 , wherein the step of categorizing the de-identified patient based on the duration between the due date of the first prescription and the fill date of the second prescription further comprises categorizing the de-identified patient as persistent if the duration is shorter than a predetermined number of days.

22. The method of claim 21 , wherein the step of categorizing the de-identified patient based on the duration between the due date of the first prescription and the fill date of the second prescription further comprises categorizing the de-identified patient as non-persistent if the duration is greater than a predetermined number of days.

23. The method of claim 22 , further comprising a step of determining, after step (i), the total number of persistent de-identified patients and the total number of non-persistent de-identified patients for each physician.

24. The method of claim 23 , further comprising a step of calculating, after the step of determining the total number of persistent de-identified patients and the total number of non-persistent de-identified patients for each physician, persistence of the physician by dividing the total number of persistent de-identified patients by the total number of de-identified patients for each physician.

25. A system for generating a profile concerning prescription therapy practices of at least one physician in a therapeutic area of interest, comprising:

(a) a mass storage device for storing a plurality of historical de-identified patient prescription records corresponding to prescriptions issued to at least one de-identified patient by at least one physician, each record including a de-identified patient identification number, dosage, number of days supplied and prescription product information, dosage, fill date, and number of days supplied;

(b) an input device, coupled to the mass storage device, for receiving user-specified information which defines a subset of the plurality of historical de-identified patient prescription records;

(c) a prescription categorizer, coupled to the input device, configured to compare the dosage and the prescription product information contained in a first historical de-identified patient prescription record with the dosage and prescription product information contained in a second historical de-identified patient prescription record, and to categorize a prescription based on a change in dosage or prescription product; and

(d) a persistence calculator, coupled to the prescription categorizer, configured to determine the due date of a first prescription based on the dosage and the number of days supplied, to compare the due date of the first prescription with the fill date of a second prescription, and to categorize the de-identified patient based on the duration between the due date of the first prescription and the fill date of the second prescription.

26. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as a new therapy start when a de-identified patient has had no other prescriptions in a therapeutic area to which the product pertains.

27. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as a therapy switch when a de-identified patient has had no other prescriptions of the product, and when the de-identified patient has had a prescription of a second product within a therapeutic area to which the product pertains that was not prescribed on the same day as the prescription.

28. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as an add-on therapy when the de-identified patient had no other prescriptions for the product but had a prescription for a second product within the therapeutic area to which the product pertains that was prescribed on the same day.

29. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as a titration decrease when a de-identified patient has previously had a prescription for the product at a higher dosage.

30. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as a titration increase when a de-identified patient has previously had a prescription for the product at a lower dosage.

31. The system of claim 25 , wherein the prescription categorizing is configured to categorize a prescription of a product as continued therapy when a de-identified patient has previously had a prescription for the product at the same dosage.

32. The system of claim 25 , wherein the persistence calculator is further configured to categorize the de-identified patient as persistent if the duration between the due date of the first prescription and the fill date of the second prescription is shorter than a predetermined number of days.

33. The system of claim 25 , wherein the persistence calculator is further configured to categorize the de-identified patient as non-persistent if the duration between the due date of the first prescription and the fill date of the second prescription is greater than a predetermined number of days.

34. The system of claim 25 , wherein the persistence calculator is further configured to determine the total number of persistent de-identified patients and the total number of non-persistent de-identified patients for each physician.

35. The system of claim 34 , wherein the persistence calculator is further configured to determine the persistence of the physician by dividing the total number of persistent de-identified patients by the total number of de-identified patients for each physician.

Assignments (11)
SECURITY INTEREST Recorded Mar 12, 2026
From: IMS SOFTWARE SERVICES LTD.; IQVIA INC.; IQVIA RDS INC.; RULES-BASED MEDICINE, INC.
To: JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 075047/0061 →
CORRECTIVE ASSIGNMENT TO CORRECT THE CONVEYING PARTIES INADVERTENTLY NOT INCLUDED IN FILING PREVIOUSLY RECORDED AT REEL: 065709 FRAME: 618. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Dec 6, 2023
From: IQVIA INC.; IQVIA RDS INC.; IMS SOFTWARE SERVICES LTD.; Q SQUARED SOLUTIONS HOLDINGS LLC
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 065790/0781 →
SECURITY INTEREST Recorded Nov 29, 2023
From: IQVIA INC.
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 065709/0618 →
SECURITY INTEREST Recorded Nov 29, 2023
From: IQVIA INC.; IQVIA RDS INC.; IMS SOFTWARE SERVICES LTD.; Q SQUARED SOLUTIONS HOLDINGS LLC
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 065710/0253 →
SECURITY INTEREST Recorded May 24, 2023
From: IQVIA INC.; IQVIA RDS INC.; IMS SOFTWARE SERVICES LTD.; Q SQUARED SOLUTIONS HOLDINGS LLC
To: U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION
Reel/Frame 063745/0279 →
CHANGE OF NAME Recorded Oct 9, 2018
From: QUINTILES IMS INCORPORATED
To: IQVIA INC.
Reel/Frame 047207/0276 →
CHANGE OF NAME Recorded Sep 7, 2018
From: IMS HEALTH INCORPORATED
To: QUINTILES IMS INCORPORATED
Reel/Frame 047029/0637 →
MERGER AND CHANGE OF NAME Recorded Jan 22, 2018
From: IMS HEALTH INCORPORATED; QUINTILES TRANSNATIONAL CORP.
To: QUINTILES IMS INCORPORATED
Reel/Frame 045102/0549 →
MERGER AND CHANGE OF NAME Recorded Feb 23, 2017
From: IMS HEALTH INCORPORATED; QUINTILES TRANSNATIONAL CORP.
To: QUINTILES IMS INCORPORATED
Reel/Frame 041791/0233 →
MERGER AND CHANGE OF NAME Recorded Jan 5, 2017
From: IMS HEALTH INCORPORATED; QUINTILES TRANSNATIONAL CORP.
To: QUINTILES IMS INCORPORATED
Reel/Frame 041260/0474 →
SECURITY AGREEMENT Recorded Mar 2, 2010
From: IMS HEALTH INCORPORATED, A DE CORP.; IMS HEALTH LICENSING ASSOCIATES, L.L.C., A DE LLC; IMS SOFTWARE SERVICES LTD., A DE CORP.
To: BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT
Reel/Frame 024006/0581 →